Browsing by Author Church, William

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Issue DateTitleAuthor(s)Citation
2011Allosteric Modulation of the Calcium-sensing Receptor by y-Glutamyl Peptides Inhibition of PTH Secretion, Suppression of Intracellular cAMP Levels and A Common Mechanism of Action with L-Amino AcidsAvlani, Vimesh Ashvinkumar; Broadhead, Geoffrey; Church, William; Conigrave, Arthur; Delbridge, Leigh; Jourdon, Orane; Mun, Hee-Chang; Christopoulos, Arthur; Molecular Bioscience; Molecular Bioscience; Pharmacy; Molecular Bioscience; Northern Clinical School: Surgery; Molecular Bioscience; Molecular BioscienceAllosteric Modulation of the Calcium-sensing Receptor by y-Glutamyl Peptides Inhibition of PTH Secretion, Suppression of Intracellular cAMP Levels and A Common Mechanism of Action with L-Amino Acids, Journal of Biological Chemistry, vol.286, 11, 2011,pp 8786-8797
2013A benchmark server using high resolution protein structure data, and benchmark results for membrane helix predictionsCampbell, Alexander; Church, William; Lee, Hong; Lee, Lawrence; Rath, Emma; Salam, Noeris; Werner, Tim; Tessier, Dominique; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyA benchmark server using high resolution protein structure data, and benchmark results for membrane helix predictions, BMC Bioinformatics, vol.14, 1, 2013,pp 1-11
2011A Bifunctional Role for Group IIA Secreted Phospholipase A2 in Human Rheumatoid Fibroblast-like Synoviocyte Arachidonic Acid MetabolismChurch, William; Lee, Lawrence; Bidgood, Matthew; Bryant, Katherine; Cahill, Michael; Courtenay, B G; Gelb, Micheal H; Graham, Garry; Kumar, Vinod; Lei, Pei-Wen; McNeil, H. Patrick; Salom, Caroline; Scott, Kieran F; Smart, Brian; Taberner, Megan; Pharmacy; PharmacyA Bifunctional Role for Group IIA Secreted Phospholipase A2 in Human Rheumatoid Fibroblast-like Synoviocyte Arachidonic Acid Metabolism, Journal of Biological Chemistry, vol.286, 4, 2011,pp 2492-2503
2017Comparative macrocycle binding of the anticancer drug phenanthriplatin by cucurbit[n]urils, (beta)-cyclodextrin and para-sulfonatocalix[4]arene: a 1H NMR and molecular modelling studyChurch, William; Kahwajy, Natalie; Kim, Ryung (Bryan); Nematollahi, Alireza; Wheate, Nial Joseph; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyComparative macrocycle binding of the anticancer drug phenanthriplatin by cucurbit[n]urils, (beta)-cyclodextrin and para-sulfonatocalix[4]arene: a 1H NMR and molecular modelling study, Journal of Inclusion Phenomena and Macrocyclic Chemistry, vol.87, N/A, 2017,pp 251-258
2007Comparative Modeling of Marsupial MHC Class I Molecules Identifies Structural Polymorphisms Affecting Functional MotifsChurch, William; Daly, Kerry; Williamson, Peter; Nicholas, Kevin; Pharmacy; Vet Science Faculty; Vet Science FacultyComparative Modeling of Marsupial MHC Class I Molecules Identifies Structural Polymorphisms Affecting Functional Motifs, Journal of Experimental Zoology. Part A: Ecological Genetics and Physiology, vol.307A,(11),2007,pp 611-624
2015Composite Model of Full GP Structure of Ebola Virus Envelope GlycoproteinChurch, William; Lynch, Garry; Portelli, Stefanie; Pharmacy; Central Clinical School: Medicine; MedicineComposite Model of Full GP Structure of Ebola Virus Envelope Glycoprotein, Journal of Molecular and Genetic Medicine, vol.9, N/A, 2015,pp 1-4
2017Crystal structure and mechanistic analysis of a novel human kynurenine aminotransferase-2 reversible inhibitorChurch, William; Hanrahan, Jane; Jayawickrama, Gayan; Nematollahi, Alireza; Sun, Guanchen; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyCrystal structure and mechanistic analysis of a novel human kynurenine aminotransferase-2 reversible inhibitor, Medicinal Chemistry Research, vol.26, 10, 2017,pp 2514-2519
2012Design and synthesis of novel inhibitors of human kynurenine aminotransferase-IAkladios, Fady; Church, William; Gorrell, Mark; Hanrahan, Jane; Nadvi, Naveed; Park, Joo Hong; Kapoor, Vimal; Chemistry; Pharmacy; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; Central Clinical School: MedicineDesign and synthesis of novel inhibitors of human kynurenine aminotransferase-I, Bioorganic & Medicinal Chemistry Letters, vol.22, 4, 2012,pp 1579-1581
2010The dipeptidyl peptidase IV family in cancer and cell biologyChowdhury, Sumaiya; Church, William; Gorrell, Mark; McCaughan, Geoffrey William; Nadvi, Naveed; Osborne, Brenna; Yao, Tsun-Wen; Yu, Ming Tse Denise; Central Clinical School: Medicine; Pharmacy; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Pharmacy; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe dipeptidyl peptidase IV family in cancer and cell biology, The FEBS Journal, vol.277, 5, 2010,pp 1126-1144
2006Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration.Church, William; Teber, Erdal; Bolton, Kent B.; Crawford, Edward; Kapoor, Vimal; Schofield, Peter R; Van Dyk, Derek; Pharmacy; PharmacyDjinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration., B M C Bioinformatics, vol.7,(33),2006,pp Article 33-1-33-9
2014Essential structural features of novel antischizophrenic drugs: a reviewAminimoghadamfarouj, Noushin; Church, William; Nematollahi, Alireza; Pharmacy; Pharmacy; PharmacyEssential structural features of novel antischizophrenic drugs: a review, Medicinal Chemistry, vol.10, 6, 2014,pp 541-549
2013Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2Church, William; Cui, Pei-Hong; Gurney, Howard; Jodal, Andreas; Murray, Michael; Wong, Ka (Mark); Zheng, Jian; Zhou, Fanfan; Zhu, Ling; Pharmacy; Pharmacy; Western Clinical School: Medicine (Westmead); Pharmacy; School of Medical Sciences: Pharmacology; Western Clinical School: Medicine (Westmead); Pharmacy; Pharmacy; Central Clinical School: Save Sight & Eye Health Inst.Functional Analysis of Novel Polymorphisms in the Human SLCO1A2 Gene that Encodes the Transporter OATP1A2, The AAPS Journal, vol.15, 4, 2013,pp 1099-1108
2010Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4)Church, William; Cui, Pei (Sarah); Murray, Michael; Zhou, Fanfan; Zhu, Ling; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Central Clinical School: Save Sight & Eye Health Inst.Functional characterization of nonsynonymous single nucleotide polymorphisms in the human organic anion transporter 4 (hOAT4), British Journal of Pharmacology, vol.159, N/A, 2010,pp 419-427
2017High resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetateAkladios, Fady; Church, William; Collyer, Charles; Gorrell, Mark; Nadvi, Naveed; Park, Joo Hong; Salam, Noeris; Kapoor, Vimal; Chemistry; Pharmacy; School of Molecular Bioscience (SMB); Central Clinical School: Centenary Institute; RADS - Research Analytics & Data Strategy; Central Clinical School: Medicine; PharmacyHigh resolution crystal structures of human kynurenine aminotransferase-I bound to PLP cofactor, and in complex with aminooxyacetate, Protein Science, vol.26, 4, 2017,pp 727-736
2014Homology Modeling of Human Kynurenine Aminotransferase III and Observations on Inhibitor Binding Using Molecular DockingChurch, William; Gorrell, Mark; Nadvi, Naveed; Nematollahi, Alireza; Sun, Guanchen; Pharmacy; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; PharmacyHomology Modeling of Human Kynurenine Aminotransferase III and Observations on Inhibitor Binding Using Molecular Docking, Central Nervous System Agents in Medicinal Chemistry, vol.14, 1, 2014,pp 2-9
2016Host-Guest Complexes of Carboxylated Pillar[n]arenes With DrugsChurch, William; Dickson, Kristie-Ann; Kayser, Veysel; Kim, Ryung (Bryan); Macquart, Rene; Marsh, Deborah; Nematollahi, Alireza; Wheate, Nial Joseph; Yu, Guocan; Pharmacy; Northern Clinical School: Medicine; Pharmacy; Pharmacy; Chemistry; Northern Clinical School: Kolling Institute; Pharmacy; PharmacyHost-Guest Complexes of Carboxylated Pillar[n]arenes With Drugs, Journal of Pharmaceutical Sciences, vol.105, 12, 2016,pp 3615-3625
2014In silico evaluation of the influence of the translocon on partitioning of membrane segmentsChurch, William; Rath, Emma; Duval, Beatrice; Hao, Jinkao; Laroum, Sami; Tessier, Dominique; Pharmacy; PharmacyIn silico evaluation of the influence of the translocon on partitioning of membrane segments, BMC Bioinformatics, vol.15, N/A, 2014,pp 156-N/A
2004Informative 3D Visualization Of Multiple Protein StructuresChurch, William; Kaplan, Warren; Lai, Paulo; Wong, Raymond K.; PharmacyInformative 3D Visualization Of Multiple Protein Structures, Proceedings of the second conference on Asia-Pacific bioinformatics, vol.N/A,(),2004,pp N/A-N/A
2017Inhibition of human kynurenine aminotransferase isozymes by estrogen and its derivativesChurch, William; Gorrell, Mark; Jayawickrama, Gayan; Nematollahi, Alireza; Sun, Guanchen; Pharmacy; Central Clinical School: Centenary Institute; Pharmacy; Pharmacy; PharmacyInhibition of human kynurenine aminotransferase isozymes by estrogen and its derivatives, Scientific Reports, vol.7, 1, 2017,pp 1-11
2013Kink characterization and modeling in transmembrane protein structuresChurch, William; Werner, Tim; Pharmacy; PharmacyKink characterization and modeling in transmembrane protein structures, Journal of Chemical Information and Modeling, vol.53, 11, 2013,pp 2926-2936