Browsing by Author Chua, Sook Wern

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Issue DateTitleAuthor(s)Citation
2015First demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO)Barron, Melissa; Hanani, Raphy; Kassiou, Michael; King, Victoria; Narlawar, Rajeshwar; Rendina, Louis; Scarf, Alana; Werry, Eryn; Chua, Sook Wern; Ittner, Lars; Martins, Ralph N.; Medical Imaging and Radiation Sciences; Chemistry; Medical Imaging and Radiation Sciences; School of Medical Sciences: Bosch Institute; Pharmacy; Chemistry; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation SciencesFirst demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO), Journal of Medicinal Chemistry, vol.58, 21, 2015,pp 8743-8749
2015First demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO)Barron, Melissa; Hanani, Raphy; Kassiou, Michael; King, Victoria; Narlawar, Rajeshwar; Rendina, Louis; Scarf, Alana; Werry, Eryn; Chua, Sook Wern; Ittner, Lars; Martins, Ralph N.; Medical Imaging and Radiation Sciences; Chemistry; Chemistry; School of Medical Sciences: Bosch Institute; Pharmacy; Chemistry; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation SciencesFirst demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO), Journal of Medicinal Chemistry, vol.58, 21, 2015,pp 8743-8749
2017The polyphenol altenusin inhibits in vitro fibrillization of tau and reduces induced tau pathology in primary neuronsKassiou, Michael; Chua, Sook Wern; Cornejo, Alberto; Cueto, Mercedes; Gladbach, Amadeus; Ittner, Lars; Lewis, Lev; Macmillan, Alexander; Stevens, Claire; Vaca, Inmaculada; van Eersel, Janet; Whan, Renee M.; ChemistryThe polyphenol altenusin inhibits in vitro fibrillization of tau and reduces induced tau pathology in primary neurons, ACS Chemical Neuroscience, vol.8, 4, 2017,pp 743-751
2017Ring-opened aminothienopyridazines as novel tau aggregation inhibitorsKassiou, Michael; Moir, Michael; Reekie, Tristan Andrew; Chua, Sook Wern; Ittner, Arne; Ittner, Lars; Martin, Andrew; Chemistry; Chemistry; Medical Imaging and Radiation SciencesRing-opened aminothienopyridazines as novel tau aggregation inhibitors, MedChemComm (Medicinal Chemistry Communications), vol.8, 6, 2017,pp 1275-1282
2016Site-specific phosphorylation of tau inhibits amyloid-b toxicity in Alzheimer's miceKril, Jillian; Mackay, Joel; Silva, Ana Paula; Suh, Lisa; Sutherland, Greg; Bertz, Josefine; Bi, Mian; Chua, Sook Wern; et al, Various; Gladbach, Amadeus; Ippati, Stefania; Ittner, Arne; Macmillan, Alexander; Przybyla, Magdalena; Stevens, Claire; van der Hoven, Julia; van Hummel, Annika; Volkerling, Alexander; Central Clinical School: Medicine; School of Molecular Bioscience (SMB); School of Molecular Bioscience (SMB); School of Medical Sciences: Pathology; School of Medical Sciences: PathologySite-specific phosphorylation of tau inhibits amyloid-b toxicity in Alzheimer's mice, Science, vol.354, 6314, 2016,pp 904-908
2014The translocator protein as a drug target in Alzheimer's diseaseKassiou, Michael; Chua, Sook Wern; Ittner, Lars; Medical Imaging and Radiation SciencesThe translocator protein as a drug target in Alzheimer's disease, Expert Review of Neurotherapeutics, vol.14, 4, 2014,pp 439-448