Browsing by Author Chen, Xin-Ming

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Issue DateTitleAuthor(s)Citation
2013Application of transmission electron tomography for modeling the renal corpuscleBraet, Filip; Chen, Xin-Ming; Cheng, Delfine; Pollock, Carol; Shen, Sylvie; School of Medical Sciences: School of Medical Sciences; Northern Clinical School: Medicine; School of Medical Sciences: Bosch Institute; Northern Clinical School: Medicine; Northern Clinical School: MedicineApplication of transmission electron tomography for modeling the renal corpuscle, Pathology, Research and Practice, vol.209, 11, 2013,pp 731-734
2013Blockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic MiceChen, Jason; Chen, Xin-Ming; Gill, Anthony; Huang, Chunling; Ma, Qing; Pollock, Carol; Shen, Sylvie; Northern Clinical School: Pathology; Northern Clinical School: Medicine; Northern Clinical School: Pathology; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: MedicineBlockade of KCa3.1 Ameliorates Renal Fibrosis Through the TGF-β1/Smad Pathway in Diabetic Mice, Diabetes, vol.62, 8, 2013,pp 2923-2934
2011Cation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-B1Chen, Xin-Ming; Panchapakesan, Usha; Pollock, Carol; Qi, Weier; Wong, Muh; Silva, Diego G.; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: MedicineCation-independent mannose 6-phosphate receptor inhibitor (PXS25) inhibits fibrosis in human proximal tubular cells by inhibiting conversion of latent to active TGF-B1, American Journal of Physiology: Renal Physiology, vol.301, 1, 2011,pp F84-F93
2009CTGF and chronic kidney fibrosisChen, Xin-Ming; Pollock, Carol; Qi, Weier; Northern Clinical School: Medicine; Northern Clinical School: MedicineCTGF and chronic kidney fibrosis, Frontiers in Bioscience, vol.1, N/A,pp 132-141
2007The differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1.Chen, Xin-Ming; Pollock, Carol; Qi, Weier; Twigg, Stephen; Gilbert, Richard E.; Kelly, Darren J.; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Molecular Medicine (Kolling I); Central Clinical School: MedicineThe differential regulation of Smad7 in kidney tubule cells by connective tissue growth factor and transforming growth factor-beta1., Nephrology, vol.12,(3),2007,pp 267-274
2010Differential Regulation of Snail by Hypoxia and Hyperglycemia in Human Proximal Tubule CellsChen, Xin-Ming; McGinn, Stella; Pollock, Carol; Saad, Sonia; Sumual, Siska; Tang, Owen; Yong, Rachel; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteDifferential Regulation of Snail by Hypoxia and Hyperglycemia in Human Proximal Tubule Cells, The International Journal of Biochemistry & Cell Biology, vol.42, 10,pp 1689-1697
2004The Effect Of High Glucose And Ppar-Gamma Agonists On Ppar-Gamma Expression And Function In Hk-2 Cells.Chen, Xin-Ming; Panchapakesan, Usha; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe Effect Of High Glucose And Ppar-Gamma Agonists On Ppar-Gamma Expression And Function In Hk-2 Cells., American Journal of Physiology: Renal Physiology, vol.287,(3),2004,pp F528-F534
2017Fluorescent labeling and biodistribution of latex nanoparticles formed by surfactant-free RAFT emulsion polymerizationChen, Xin-Ming; Hawkett, Brian; Kim, Byung Juen; Perrier, Sebastien; Pollock, Carol; Poon, Cheuk Ka; Tang, Owen; Hartlieb, Matthias; Northern Clinical School: Medicine; Chemistry; Chemistry; Chemistry; Northern Clinical School: Medicine; Chemistry; Northern Clinical School: MedicineFluorescent labeling and biodistribution of latex nanoparticles formed by surfactant-free RAFT emulsion polymerization, Macromolecular Bioscience, vol.17, 10, 2017,pp 1-10
2009High glucose induced endothelial cell growth inhibition is associated with an increase in TGF-{beta}(1) secretion and inhibition of Ras prenylation via suppression of the mevalonate pathwayChen, Xin-Ming; Field, Michael; Mather, Amanda; McGinn, Catherine Mary; Pollock, Carol; Sumual, Siska; Kelly, Darren J.; Mangiafico, S; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Clinical Schools; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteHigh glucose induced endothelial cell growth inhibition is associated with an increase in TGF-{beta}(1) secretion and inhibition of Ras prenylation via suppression of the mevalonate pathway, The International Journal of Biochemistry and Cell Biology, vol.41, 3, 2009,pp 561-569
2014High Glucose Induces CCL20 in Proximal Tubular Cells via Activation of the KCa3.1 ChannelChen, Xin-Ming; Huang, Chunling; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: MedicineHigh Glucose Induces CCL20 in Proximal Tubular Cells via Activation of the KCa3.1 Channel, PloS One, vol.9, 4, 2014,pp 1-8
2007High glucose induces macrophage inflammatory protein-3{alpha} in renal proximal tubule cells via a transforming growth factor-{beta}1 dependent mechanismChen, Xin-Ming; Holian, John; Mreich, Ellein; Pollock, Carol; Qi, Weier; Gilbert, Richard E.; Kelly, Darren J.; Zhang, Yuan; Northern Clinical School: Medicine; Clinical Schools; Medicine; Northern Clinical School: Medicine; Northern Clinical School: Molecular Medicine (Kolling I)High glucose induces macrophage inflammatory protein-3{alpha} in renal proximal tubule cells via a transforming growth factor-{beta}1 dependent mechanism, Nephrology Dialysis Transplantation (2005), vol.22,(11),2007,pp 3147-3153
2007High Glucose-Induced Thioredoxin-Interacting Protein in Renal Proximal Tubule Cells Is Independent of Transforming Growth Factor-{beta}1Chen, Xin-Ming; Pollock, Carol; Qi, Weier; Gilbert, Richard E.; Kelly, Darren J.; Schache, Maria; Waltham, Mark; Zhang, Yuan; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteHigh Glucose-Induced Thioredoxin-Interacting Protein in Renal Proximal Tubule Cells Is Independent of Transforming Growth Factor-{beta}1, The American Journal of Pathology: cellular and molecular biology of disease, vol.171,(3),2007,pp 744-754
2016Increased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathyChen, Xin-Ming; Pollock, Carol; Saad, Sonia; Yaghobian, Dania; Yaghobian, Sarina; Don, Anthony; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling InstituteIncreased sphingosine 1-phosphate mediates inflammation and fibrosis in tubular injury in diabetic nephropathy, Clinical and Experimental Pharmacology and Physiology, vol.43, 1, 2016,pp 56-66
2014Inhibition of KCa3.1 suppresses TGF-Beta1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathwaysChen, Xin-Ming; Day, Margot; Huang, Chunling; Pollock, Carol; Poronnik, Philip; Northern Clinical School: Medicine; School of Medical Sciences: Physiology; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; School of Medical Sciences: PhysiologyInhibition of KCa3.1 suppresses TGF-Beta1 induced MCP-1 expression in human proximal tubular cells through Smad3, p38 and ERK1/2 signaling pathways, The International Journal of Biochemistry and Cell Biology, vol.47, 1, 2014,pp 1-10
2005Integrated actions of transforming growth factor-beta(1) and connective tissue growth factor in renal fibrosis.Chen, Xin-Ming; Polhill, Tania; Pollock, Carol; Poronnik, Philip; Qi, Weier; Twigg, Stephen; Gilbert, Richard E.; Northern Clinical School: Medicine; Northern Clinical School: NCS Office; Northern Clinical School: Medicine; Medicine Faculty Office; Northern Clinical School: Molecular Medicine (Kolling I); Central Clinical School: MedicineIntegrated actions of transforming growth factor-beta(1) and connective tissue growth factor in renal fibrosis., American Journal of Physiology: Renal Physiology, vol.288,(4),2005,pp F800-F809
2007The interdependence of EGF-R and SGK-1 in fibronectin expression in primary kidney cortical fibroblast cellsChen, Xin-Ming; Pollock, Carol; Saad, Sonia; Stevens, Veronica; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: MedicineThe interdependence of EGF-R and SGK-1 in fibronectin expression in primary kidney cortical fibroblast cells, The International Journal of Biochemistry & Cell Biology, vol.39,(5),2007,pp 1047-1054
2007Isolation, propagation and characterization of primary tubule cell culture from human kidneyChen, Xin-Ming; Pollock, Carol; Qi, Weier; Johnson, David W; Vesey, David A; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Molecular Medicine (Kolling I)Isolation, propagation and characterization of primary tubule cell culture from human kidney, Nephrology, vol.12,(2),2007,pp 155-159
2014KCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosisChen, Xin-Ming; Gill, Anthony; Huang, Chunling; Ma, Qing; Pollock, Carol; Shen, Sylvie; Northern Clinical School: Medicine; Deans Unit: (CIPHER); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Medicine; Northern Clinical School: MedicineKCa3.1 mediates activation of fibroblasts in diabetic renal interstitial fibrosis, Nephrology, Dialysis, Transplantation, vol.29, 2, 2014,pp 313-324
2016KCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathwaysBraet, Filip; Chen, Xin-Ming; Cheng, Delfine; Huang, Chunling; Lin, Zhen (Mike); Pollock, Carol; School of Medical Sciences: Anatomy & Histology; Northern Clinical School: Medicine; School of Medical Sciences: Bosch Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: MedicineKCa3.1 mediates dysfunction of tubular autophagy in diabetic kidneys via PI3k/Akt/mTOR signaling pathways, Scientific Reports, vol.6, N/A, 2016,pp 1-12
2015KCa3.1: a new player in progressive kidney diseaseChen, Xin-Ming; Huang, Chunling; Pollock, Carol; Northern Clinical School: Medicine; Northern Clinical School: Kolling Institute; Northern Clinical School: MedicineKCa3.1: a new player in progressive kidney disease, Current Opinion In Nephrology And Hypertension, vol.24, 1, 2015,pp 61-66