Browsing by Author Carland, Jane

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Issue DateTitleAuthor(s)Citation
2004Charged Residues At The 2' Position Of Human GABAc ρ1 Receptors Invert Ion Selectivity And Influence Open State Probability.Carland, Jane; Collins (Chebib), Mary; Johnston, Graham; Moorhouse, Andrew; Barry, Peter H; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Medicine Faculty OfficeCharged Residues At The 2' Position Of Human GABAc ρ1 Receptors Invert Ion Selectivity And Influence Open State Probability., Journal of Biological Chemistry, vol.279,(52),2004,pp 54153-54160
2012Differentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABAC rho1 ReceptorsAbsalom, Nathan Luke; Carland, Jane; Collins, Mary; Doddareddy, Munikumar; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Yamamoto, Izumi; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Brain and Mind Centre; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyDifferentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABAC rho1 Receptors, ACS Chemical Neuroscience, vol.3, 9, 2012,pp 665-673
2013Directed Mutagenesis in Structure Activity Studies of Neurotransmitter TransportersCarland, Jane; Edington, Amelia; Ryan, Renae; Scopelliti, Amanda J; Vandenberg, Robert; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: PharmacologyDirected Mutagenesis in Structure Activity Studies of Neurotransmitter Transporters in Genetic Manipulation of DNA and Protein - Examples from Current Research, InTech Publishers, 2013, pp. 167-184
2014Glycine transport inhibitors for the treatment of painCarland, Jane; Christie, MacDonald; Imlach, Wendy Louise; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyGlycine transport inhibitors for the treatment of pain, Trends In Pharmacological Sciences, vol.35, 8, 2014,pp 423-430
2016Glycine Transporter2 Inhibitors: Getting the balance rightCarland, Jane; Mostyn, Shannon; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; Medicine; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyGlycine Transporter2 Inhibitors: Getting the balance right, Neurochemistry International, vol.98, N/A, 2016,pp 89-93
2016Identification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2Carland, Jane; Ryan, Renae; Scopelitti, Amanda; Vandenberg, Robert; O'Mara, Megan; Subramanian, Nandhitha; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: PharmacologyIdentification of a 3rd Na+ Binding Site of the Glycine Transporter, GlyT2, PloS One, vol.11, 6, 2016,pp 1-16
2014Lipid Inhibitors of High Affinity Glycine Transporters: Identification of a novel class of analgesicsCarland, Jane; Handford, Cheryl; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyLipid Inhibitors of High Affinity Glycine Transporters: Identification of a novel class of analgesics, Neurochemistry International, vol.73, N/A, 2014,pp 211-216
2005Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptorsBarker, David; Carland, Jane; Chu, Cindy; Collins (Chebib), Mary; Lin, Diana; McLeod, Malcolm; Brimble, Margaret; Savage, G Paul; Chemistry; Pharmacy; Pharmacy; Pharmacy; Pharmacy; ChemistryMethyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors, Bioorganic & Medicinal Chemistry, vol.13,(14),2005,pp 4565-4575
2004Mutations Of The 2' Proline In The M2 Domain Of The Human Gabac Rho1 Subunit Alter Agonist Responses.Carland, Jane; Collins (Chebib), Mary; Duke, Rujee; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Moore, Allison; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; PharmacyMutations Of The 2' Proline In The M2 Domain Of The Human Gabac Rho1 Subunit Alter Agonist Responses., Neuropharmacology (2005), vol.46,(N/A),2004,pp 770-781
2013Oleoyl-L-carnitine inhibits glycine transport by GlyT2Carland, Jane; Mansfield, Robyn; Ryan, Renae; Vandenberg, Robert; School of Medical Sciences: Pharmacology; Molecular Bioscience; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyOleoyl-L-carnitine inhibits glycine transport by GlyT2, British Journal of Pharmacology, vol.168, 4, 2013,pp 891-902
2008Relative impact of residues at the intracellular and extracellular ends of the human GABA(C) rho1 receptor M2 domain on picrotoxinin activityCarland, Jane; Collins, Mary; Johnston, Graham; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: PharmacologyRelative impact of residues at the intracellular and extracellular ends of the human GABA(C) rho1 receptor M2 domain on picrotoxinin activity, European Journal of Pharmacology, vol.580, 1, 2008,pp 27-35
2012Structurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the p1 ReceptorAbsalom, Nathan; Allan, Robin; Carland, Jane; Collins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Locock, Katherine; Yamamoto, Izumi; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; PharmacyStructurally Diverse GABA Antagonists Interact Differently with Open and Closed Conformational States of the p1 Receptor, ACS Chemical Neuroscience, vol.3, 4, 2012,pp 293-301
2017Synthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2Carland, Jane; Mostyn, Shannon; Ryan, Renae; Vandenberg, Robert; Rawling, Tristan; Shimmon, Susan; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologySynthesis and Characterization of Novel Acyl-Glycine Inhibitors of GlyT2, ACS Chemical Neuroscience, vol.8, 9, 2017,pp 1949-1959