Browsing by Author Bryan, Tracy

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Issue DateTitleAuthor(s)Citation
2003Alternative lengthening of telomeres: dangerous road less travelledBryan, Tracy; Reddel, Roger R; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres: dangerous road less travelled, The Lancet, vol.361,(9372),2003,pp 1840-1841
2008Amplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression LevelsBryan, Tracy; Cao, Ying; Chang, Andy; Huschtscha, Lily; Neumann, Axel; Nouwens, Amanda; Pickett, Hilda; Reddel, Roger; Toouli, Christian; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Concord Clinical School: Age & Alzh Dis Rrch Educ; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAmplification of Telomerase Reverse Transcriptase Gene in Human Mammary Epithelial Cells with Limiting Telomerase RNA Expression Levels, Cancer Research, vol.68, 9, 2008,pp 3115-3123
2015ATM and ATR Signaling Regulate the Recruitment of Human Telomerase to TelomeresBryan, Tracy; Kartawinata, Melissa; Stern, Josh; Tong, A; De Lange, Titia; Sfeir, Agnel J; Zhu, Xu-Dong; Childrens Medical Research Institute (CMRI); Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsATM and ATR Signaling Regulate the Recruitment of Human Telomerase to Telomeres, Cell Reports, vol.13, 8, 2015,pp 1-14
2016The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNABryan, Tracy; Mathias, Jordan; Tomlinson, Christopher; Holien, Jessica; Parker, Michael; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)The C-terminal extension of human telomerase reverse transcriptase is necessary for high affinity binding to telomeric DNA, Biochimie, vol.128-129, N/A, 2016,pp 114-121
2017Cancer-Associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expressionBryan, Tracy; Moye, Aaron; Christ, D; Cowley, M; Dinger, M; Perera, D; Wong, J; Zeraati, M; Childrens Medical Research Institute (CMRI); Children's Hospital Westmead: Childrens Medical Research InsCancer-Associated noncoding mutations affect RNA G-quadruplex-mediated regulation of gene expression, Scientific Reports, vol.7, 1, 2017,pp 1-11
2015A Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of TelomeraseBryan, Tracy; Killedar, Anagha; Pickett, Hilda; Reddel, Roger; Sobinoff, Alexander; Stutz, Michael D.; Tomlinson, Christopher; Beesley, Jonathan; Chenevix-Trench, Georgia; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Medicine; Central Clinical School: Medicine; Children's Hospital Westmead: Childrens Medical Research InsA Common Cancer Risk-Associated Allele in the hTERT Locus Encodes a Dominant Negative Inhibitor of Telomerase, PLoS Genetics, vol.11, 6, 2015,pp 1-23
2010Direct involvement of the TEN domain at the active site of human telomeraseBryan, Tracy; Cohen, Scott; Jurczyluk, Julie; Nouwens, Amanda; Adams, Timothy E.; Holien, Jessica; Lovrecz, George; Parker, Michael W; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsDirect involvement of the TEN domain at the active site of human telomerase, Nucleic Acids Research, vol.N/A, N/A,pp 1-15
2015ESI-MS Investigation of an Equilibrium between a Bimolecular Quadruplex DNA and a Duplex DNA/RNA HybridBryan, Tracy; Beck, Jennifer L; Birrento, Monica L; Samosorn, Siritron; Children's Hospital Westmead: Childrens Medical Research InsESI-MS Investigation of an Equilibrium between a Bimolecular Quadruplex DNA and a Duplex DNA/RNA Hybrid, Journal of the American Society for Mass Spectrometry, vol.26, 7, 2015,pp 1165-1173
2006Extension of G-quadruplex DNA by ciliate telomerase.Bryan, Tracy; Oganesian, Liana; Jarstfer, Michael B.; Moon, Ian K.; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsExtension of G-quadruplex DNA by ciliate telomerase., The EMBO Journal, vol.25,(5),2006,pp 1148-1159
2011G-Quadruplexes: From Guanine Gels to ChemotherapeuticsBryan, Tracy; Baumann, Peter; Children's Hospital Westmead: Childrens Medical Research InsG-Quadruplexes: From Guanine Gels to Chemotherapeutics, Molecular Biotechnology, vol.49, 2, 2011,pp 198-208
2014Inherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1Al-Odaib, Ahmad; Barbaro, Pasquale; Bryan, Tracy; Christodoulou, John; Kartawinata, Melissa; Pickett, Hilda; Reddel, Roger; Chen, Yulan; Guo, Yiran; Hakonarson, Haron; Keating, Brendan; Kilo, Tatjana; Li, Jiankang; Teo, Juliana; Tian, Lifeng; Xu, Xun; Childrens Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Childrens Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsInherited bone marrow failure associated with germline mutation of ACD, the gene encoding telomere protein TPP1, Blood, vol.124, 18, 2014,pp 2767-2774
2014Inhibition of Telomerase: Promise, Progress and Potential PitfallsBryan, Tracy; Cohen, Scott; Tomlinson, Christopher; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Inhibition of Telomerase: Promise, Progress and Potential Pitfalls in Cancer Drug Design and Discovery, Academic Press, 2014, pp. 491-527
2007Interrogation of G-quadruplex-protein interactionsBryan, Tracy; Jarstfer, Michael B.; Children's Hospital Westmead: Childrens Medical Research InsInterrogation of G-quadruplex-protein interactions, Methods, vol.43,(4),2007,pp 332-339
2008Multiple DNA-binding sites in Tetrahymena telomeraseBryan, Tracy; Finger, Sharon; Children's Hospital Westmead: Childrens Medical Research Ins; School of Medical Sciences: Anatomy & HistologyMultiple DNA-binding sites in Tetrahymena telomerase, Nucleic Acids Research, vol.36,(4),2008,pp 1260-1272
2007Physiological relevance of telomeric G-quadruplex formation: a potential drug targetBryan, Tracy; Oganesian, Liana; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsPhysiological relevance of telomeric G-quadruplex formation: a potential drug target, BioEssays: advances in molecular, cellular and developmental biology, vol.29,(2),2007,pp 155-165
2017Quantitative assays for measuring human telomerase activity and DNA binding propertiesBryan, Tracy; Cohen, Scott; Jurczyluk, Julie; Sasaki, Natsuki; Tomlinson, Christopher; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Childrens Medical Research Ins; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI)Quantitative assays for measuring human telomerase activity and DNA binding properties, Methods, vol.114, N/A, 2017,pp 85-95
2006Structure of stem-loop IV of Tetrahymena telomerase RNA.Bryan, Tracy; Chen, Yu; Fender, Jessica; Jarstfer, Michael B.; Legassie, Jason D.; Varani, Gabriele; Children's Hospital Westmead: Childrens Medical Research InsStructure of stem-loop IV of Tetrahymena telomerase RNA., The EMBO Journal, vol.25,(13),2006,pp 3156-3166
2007Telomerase Recognizes G-Quadruplex and Linear DNA as Distinct SubstratesBryan, Tracy; Graham, Mark; Oganesian, Liana; Robinson, Phillip; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsTelomerase Recognizes G-Quadruplex and Linear DNA as Distinct Substrates, Biochemistry 2005, vol.46,(40),2007,pp 11279-11290
2012Telomerase Recruitment Requires both TCAB1 and Cajal Bodies IndependentlyBryan, Tracy; Cohen, Scott; Pickett, Hilda; Stern, Josh; Zyner, Katherine; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsTelomerase Recruitment Requires both TCAB1 and Cajal Bodies Independently, Molecular and Cellular Biology, vol.32, 13, 2012,pp 2384-2395
2008Telomerase recruitment to telomeresBryan, Tracy; Stern, Josh; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsTelomerase recruitment to telomeres, Cytogenetic and Genome Research, vol.122, 3-4, 2008,pp 243-254