Browsing by Author Bertolino, Patrick

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Issue DateTitleAuthor(s)Citation
2014Antigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responsesBertolino, Patrick; Bishop, Alex; Bowen, David; Gamble, Jennifer; McCaughan, Geoffrey William; McDonald, David M; McGuffog, Claire; Roediger, Ben; Sierro, Frederic; Tay, Szun; Weninger, Wolfgang; Wong, Yik Chun; Wood, Nicole; Alexander, Ian E; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Infectious Diseases; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: AW Morrow Gastroenterology and LivAntigen expression level threshold tunes the fate of CD8 T cells during primary hepatic immune responses, Proceedings of the National Academy of Sciences (PNAS) of the United States of America, vol.111, 25, 2014,pp E2540-E2549
2002Autocrine IL-10 impairs dendritic cell (DC)-derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL-12 productionBertolino, Patrick; Britton, Warwick; Demangel, Caroline; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteAutocrine IL-10 impairs dendritic cell (DC)-derived immune responses to mycobacterial infection by suppressing DC trafficking to draining lymph nodes and local IL-12 production, European Journal of Immunology, vol.32,(4),2002,pp 994-1002
2015Caveolae control the anti-inflammatory phenotype of senescent endothelial cellsBertolino, Patrick; Coleman, Paul; Gamble, Jennifer; Lay, Angelina; Powter, Elizabeth; Tran, Minh; Vadas, Mathew; Parton, Robert G.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteCaveolae control the anti-inflammatory phenotype of senescent endothelial cells, Aging Cell, vol.14, 1, 2015,pp 102-111
2010CD8+ T cell tolerance following antigen recognition on hepatocytes.Bertolino, Patrick; Bowen, David; Holz, Lauren; Le Couteur, David; Warren, Alessandra; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteCD8+ T cell tolerance following antigen recognition on hepatocytes., Journal of Autoimmunity, vol.34, 1,pp 15-22
2008Cell-mediated rejection results in allograft loss after liver cell transplantationBertolino, Patrick; Allen, Katrina J.; Hardikar, Winita; Mifsud, Nicole A.; Williamson, Robert; Central Clinical School: Centenary InstituteCell-mediated rejection results in allograft loss after liver cell transplantation, Liver Transplantation, vol.14, 5, 2008,pp 688-694
2002Cytokine-dependent bystander hepatitis due to intrahepatic murine CD8+ T-cell activation by bone marrow-derived cellsBertolino, Patrick; Bowen, David; Davis, Tracey; Fazekas De St Groth, Barbara; McCaughan, Geoffrey; Warren, Alessandra; Hoffmann, Matthias W; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research InstituteCytokine-dependent bystander hepatitis due to intrahepatic murine CD8+ T-cell activation by bone marrow-derived cells, Gastroenterology, vol.123,(4),2002,pp 1252-1264
2013Differential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation.Benseler, Volker; Bertolino, Patrick; Bishop, George (Alex); Bowen, David; McCaughan, Geoffrey; McGuffog, Claire; Sierro, Frederic; Tay, Szun; Cowan, Peter J; Dwyer, Karen; Lu, Bo; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryDifferential migration of passenger leukocytes and rapid deletion of naive alloreactive CD8 T cells after mouse liver transplantation., Liver Transplantation, vol.19, 11, 2013,pp 1224-1235
2005Early intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice.Bertolino, Patrick; Bowen, David; Holz, Lauren; McCaughan, Geoffrey; Eulenburg, Katharina; Ghani, Saeed; Hamann, Alf; Hogg, Nancy; Klugewitz, Katja; Schrage, Arnhild; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteEarly intrahepatic antigen-specific retention of naïve CD8+ T cells is predominantly ICAM-1/LFA-1 dependent in mice., Hepatology, vol.42,(5),2005,pp 1063-1071
2016Effector T cell function rather than survival determines extent and duration of hepatitis in miceBenseler, Volker; Bertolino, Patrick; Bowen, David; English, Kieran; Holz, Lauren; McCaughan, Geoffrey William; McGuffog, Claire; Vo, Michelle; Wong, Yik Chun; Azuma, Miyuki; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteEffector T cell function rather than survival determines extent and duration of hepatitis in mice, Journal of Hepatology, vol.64, 6, 2016,pp 1327-1338
2005Examination of immune mechanisms in a mouse model of spontaneous renal allograft acceptanceBertolino, Patrick; Bishop, George (Alex); Cordoba, Shaun; Li, Jian; McCaughan, Geoffrey; Wang, Chuanmin; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryExamination of immune mechanisms in a mouse model of spontaneous renal allograft acceptance, Immunology and Cell Biology, vol.83,(4 Supplement),2005,pp A20-A21
2013Gene therapy for tolerance: high-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin graftsAlexander, Ian; Bertolino, Patrick; Bishop, Alex; Bowen, David; Cubitt, Jonathan; Cunningham, Eithne; McCaughan, Geoffrey William; McGuffog, Claire; Rtshiladze, Michael; Sharland, Alexandra; Tay, Szun; Wang, Chuanmin; Wang, Zane; Children's Hospital Westmead: Paediatrics & Child Health; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Bosch Institute; Central Clinical School: Medicine; Central Clinical School: Surgery; Central Clinical School: Surgery; School of Medical Sciences: Bosch InstituteGene therapy for tolerance: high-level expression of donor major histocompatibility complex in the liver overcomes naive and memory alloresponses to skin grafts, Transplantation, vol.95, 1, 2013,pp 70-77
2002Growth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b)Bertolino, Patrick; Adams, Timothy E.; Alexander, Warren S.; Asa, Sylvia L.; Corbin, Jason E.; Davey, Helen W.; Greenhalgh, Christopher J.; Hilton, Douglas J.; Metcalf, Donald; Nicola, Nicos A.; Central Clinical School: Centenary InstituteGrowth enhancement in suppressor of cytokine signaling 2 (SOCS-2)-deficient mice is dependent on signal transducer and activator of transcription 5b (STAT5b), Molecular Endocrinology, vol.16,(6),2002,pp 1394-1406
2005Hepatic pseudocapillarization in aged mice.Bertolino, Patrick; Cogger, Victoria; Le Couteur, David; Warren, Alessandra; Fraser, Robin; McLean, Allan J; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteHepatic pseudocapillarization in aged mice., Experimental Gerontology, vol.40,(10),2005,pp 807-812
2011Hepatocyte entry leads to degradation of autoreactive CD8 T cellsBenseler, Volker; Bertolino, Patrick; Bowen, David; Breen, Eamon; Holz, Lauren; Le Couteur, David; McCaughan, Geoffrey William; McGuffog, Claire; Tay, Szun; Vo, Michelle; Warren, Alessandra; Allison, Anthony C; Schlitt, Hans Juergen; Van Rooijen, Nico; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research InstituteHepatocyte entry leads to degradation of autoreactive CD8 T cells, Proceedings of the National Academy of Sciences of the United States of America (PNAS), vol.108, 40, 2011,pp 16735-16740
2015Immune outcomes in the liver: Is CD8 T cell fate determined by the environment?Bertolino, Patrick; Bowen, David; McCaughan, Geoffrey William; Tay, Szun; Wong, Yik Chun; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Central Clinical School: Centenary InstituteImmune outcomes in the liver: Is CD8 T cell fate determined by the environment?, Journal of Hepatology, vol.63, 4, 2015,pp 1005-1014
2006Immune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells.Bertolino, Patrick; Bowen, David; Dahlke, Marc-Hendrik; Holz, Lauren; McCaughan, Geoffrey; Schlitt, Hans; Loi, Roberto; Piso, Pompiliu; Popp, Felix C.; Warren, Alessandra; Weiss, Daniel J.; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Clinical SchoolsImmune-mediated hepatitis drives low-level fusion between hepatocytes and adult bone marrow cells., Journal of hepatology, vol.44,(2),2006,pp 334-341
2011The Impact of Poloxamer 407 on the Ultrastructure of the Liver and Evidence for Clearance by Extensive Endothelial and Kupffer Cell EndocytosisBenseler, Volker; Bertolino, Patrick; Cogger, Victoria; Le Couteur, David; Warren, Alessandra; Medicine; Central Clinical School: Centenary Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteThe Impact of Poloxamer 407 on the Ultrastructure of the Liver and Evidence for Clearance by Extensive Endothelial and Kupffer Cell Endocytosis, Toxicologic Pathology, vol.39, 2, 2011,pp 390-397
2015The influence of macronutrients on splanchnic and hepatic lymphocytes in aging miceBertolino, Patrick; Cogger, Victoria Carroll; Colakoglu, Feyza; Holmes, Andrew; Le Couteur, David; McMahon, Aisling; Raubenheimer, David; Simpson, Stephen; Solon-Biet, Samantha Marie; Tay, Szun; Warren, Alessandra; Ballard, J. William O.; Correa, Carolina; Horan, Martin Patrick; Melvin, Richard; Pichaud, Nicolas; Ruohonen, Kari; Turner, Nigel; Central Clinical School: Centenary Institute; Medicine; Molecular Bioscience; Molecular Bioscience; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Vet Science Faculty; Biological Sciences; Charles Perkins Centre; Central Clinical School: Surgery; Concord Clinical School: ANZAC Research InstituteThe influence of macronutrients on splanchnic and hepatic lymphocytes in aging mice, Journals of Gerontology. Series A: Biological Sciences and Medical Sciences, vol.70, 12, 2015,pp 1499-1507
2008Interleukin-22, interleukin-17, and other cytokines: a wall is coming downBertolino, Patrick; Central Clinical School: Centenary InstituteInterleukin-22, interleukin-17, and other cytokines: a wall is coming down, Hepatology, vol.47,(1),2008,pp 345-348
2014Intrahepatic activation of naive CD4+T cells by liver-resident phagocytic cellsAlexander, Ian; Bertolino, Patrick; Bishop, Alex; Bowen, David; Gamble, Jennifer; McCaughan, Geoffrey William; McDonald, David M; McGuffog, Claire; Meyer, Nicolas; Roediger, Ben; Sierro, Frederic; Tay, Szun; Weninger, Wolfgang; Wong, Yik Chun; Heath, William R; Lu, Bo; Parish, Ian A; Childrens Hospital Westmead: Paediatrics & Child Health; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Infectious Diseases; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteIntrahepatic activation of naive CD4+T cells by liver-resident phagocytic cells, The Journal of Immunology, vol.193, 5, 2014,pp 2087-N/A