Browsing by Author Bernhardt, Paul V

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Showing results 1 to 11 of 11
Issue DateTitleAuthor(s)Citation
2013Alkyl Substituted 2'-Benzoylpyridine Thiosemicarbazone Chelators with Potent and Selective Anti-Neoplastic Activity: Novel Ligands that Limit Methemoglobin FormationGutierrez, Elaine; Jansson, Jan (Patric); Kalinowski, Danuta; Richardson, Desi (Des); Stefani, Christian; Bernhardt, Paul V; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyAlkyl Substituted 2'-Benzoylpyridine Thiosemicarbazone Chelators with Potent and Selective Anti-Neoplastic Activity: Novel Ligands that Limit Methemoglobin Formation, Journal of Medicinal Chemistry, vol.56, 1, 2013,pp 357-370
2007Design, Synthesis, and Characterization of Novel Iron Chelators: Structure-Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor AgentsKalinowski, Danuta; Lovejoy, David; Richardson, Desi; Yu, Yu; Bernhardt, Paul V; Islam, Mohammad; Kumar, Naresh; Liao, Yi-Tyng; Sharpe, Philip C; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyDesign, Synthesis, and Characterization of Novel Iron Chelators: Structure-Activity Relationships of the 2-Benzoylpyridine Thiosemicarbazone Series and Their 3-Nitrobenzoyl Analogues as Potent Antitumor Agents, Journal of Medicinal Chemistry, vol.50,(15),2007,pp 3716-3729
2007Hydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activityRichardson, Desmond; Bernhardt, Paul V; Chin, Piao; Sharpe, Philip C; School of Medical Sciences: PathologyHydrazone chelators for the treatment of iron overload disorders: iron coordination chemistry and biological activity, Dalton Transactions, vol.30,(N/A),2007,pp 3232-3244
2014Kinetic studies on the oxidation of oxyhemoglobin by biologically active iron thiosemicarbazone complexes: relevance to iron-chelator-induced methemoglobinemiaRichardson, Desi (Des); Basha, Maram; Bernhardt, Paul V; Martínez, Manuel; Rodríguez, Carlos; School of Medical Sciences: PathologyKinetic studies on the oxidation of oxyhemoglobin by biologically active iron thiosemicarbazone complexes: relevance to iron-chelator-induced methemoglobinemia, Journal of Biological Inorganic Chemistry, vol.19, 3, 2014,pp 349-357
2016Kinetico-mechanistic studies on methemoglobin generation by biologically active thiosemicarbazone iron(III) complexesRichardson, Desi (Des); Basha, Maram; Bernhardt, Paul V; Bordini, Jeane; Martinez, Manuel; School of Medical Sciences: PathologyKinetico-mechanistic studies on methemoglobin generation by biologically active thiosemicarbazone iron(III) complexes, Journal of Inorganic Biochemistry, vol.162, N/A, 2016,pp 326-333
2017A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's diseaseAnjum, Rukhsana; Hibbs, David; Kalinowski, Danuta; Lin, Hsuan-Yu Jennifer; Palanimuthu, Duraippandi; Poon, Rachal; Richardson, Desi (Des); Sahni, Sumit; Bernhardt, Paul V; School of Medical Sciences: Pathology; Pharmacy; School of Medical Sciences: Pathology; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyA novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease, European Journal of Medicinal Chemistry, vol.139, N/A, 2017,pp 612-632
2015Structural basis of interprotein electron transfer in bacterial sulfite oxidationGuss, Mitchell; Laming, Elise; Trewhella, Jill; Bernhardt, Paul V; Calmes, Benoit; Casas Garcia, G Patricia; Hanson, Graeme R; Kappler, Ulrike; Kvansakul, Marc; Maher, Megan J.; McGrath, Aaron; Molecular Bioscience; Medicine; DVC Research & InnovationStructural basis of interprotein electron transfer in bacterial sulfite oxidation, eLife, vol.4, N/A, 2015,pp 1-26
2016Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug ResistanceJansson, Patric; Kalinowski, Danuta; Palanimuthu, Duraippandi; Richardson, Desi (Des); Stacy, Alexandra Elizabeth; Bernhardt, Paul V; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyStructure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance, Journal of Medicinal Chemistry, vol.59, 18, 2016,pp 8601-8620
2016Structure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug ResistanceJansson, Patric; Kalinowski, Danuta; Palanimuthu, Duraippandi; Richardson, Desi (Des); Stacy, Alexandra Elizabeth; Bernhardt, Paul V; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyStructure-Activity Relationships of Di-2-pyridylketone, 2-Benzoylpyridine, and 2-Acetylpyridine Thiosemicarbazones for Overcoming Pgp-Mediated Drug Resistance, Journal of Medicinal Chemistry, vol.59, 18, 2016,pp 8601-8620
2008Tuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligandsKalinowski,, Danuta; Richardson, Desi; Bernhardt, Paul V; Sharpe, Philip C; Wilson, Gregory J; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyTuning the antiproliferative activity of biologically active iron chelators: characterization of the coordination chemistry and biological efficacy of 2-acetylpyridine and 2-benzoylpyridine hydrazone ligands, Journal of Biological Inorganic Chemistry, vol.13,(1),2008,pp 107-119
2016Zinc(II)-Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce CytotoxicityJansson, Patric; Kalinowski, Danuta; Palanimuthu, Duraippandi; Richardson, Desi (Des); Stacy, Alexandra Elizabeth; Bernhardt, Paul V; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Central Clinical School: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyZinc(II)-Thiosemicarbazone Complexes Are Localized to the Lysosomal Compartment Where They Transmetallate with Copper Ions to Induce Cytotoxicity, Journal of Medicinal Chemistry, vol.59, 10, 2016,pp 4965-4984