Browsing by Author Alewood, Paul F

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Showing results 1 to 19 of 19
Issue DateTitleAuthor(s)Citation
2010Analgesic omega-Conotoxins CVIE and CVIF Selectively and Voltage-Dependently Block Recombinant and Native N-Type Calcium ChannelsChristie, MacDonald; Moretta, M.; Adams, D. J.; Alewood, Paul F; Bansal, Paramjit S; Berecki, G.; Drinkwater, R; Haythornthwaite, A.; Lewis, Richard J.; Motin, L; Vink, S.; Wang, Ching-I A; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: OfficeAnalgesic omega-Conotoxins CVIE and CVIF Selectively and Voltage-Dependently Block Recombinant and Native N-Type Calcium Channels, Molecular Pharmacology, vol.77, 2,pp 139-148
2012Characterisation of Nav types endogenously expressed in human SH-SY5Y neuroblastoma cellsChristie, MacDonald; Mozar, Christine; Alewood, Paul F; Durek, Thomas; Lewis, Richard; Vetter, Irina; Wingerd, Joshua; School of Medical Sciences: Pharmacology; School of Medical Sciences: Brain & Mind Research InstituteCharacterisation of Nav types endogenously expressed in human SH-SY5Y neuroblastoma cells, Biochemical Pharmacology, vol.83, 11, 2012,pp 1562-1571
2006Characterization and isolation of L-to-D-amino-acid-residue isomerase from Platypus venomBelov, Katherine; Kennett, Eleanor; Kuchel, Philip; Torres, Allan; Tsampazi, Chryssanthi; Alewood, Paul F; Bansal, Paramjit S; Geraghty, Dominic P; Vet Science Faculty; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceCharacterization and isolation of L-to-D-amino-acid-residue isomerase from Platypus venom, Amino Acids, vol.32,(1),2006,pp 63-68
2010Chemical Synthesis and Structure of the Prokineticin Bv8Christie, MacDonald; Napier, Ian; Alewood, Paul F; Craik, D J; Daly, Norelle L.; Durek, Thomas; King, Glenn; Lewis, Richard J.; Mobli, Mehdi; Morales, Rodrigo A. V.; Vetter, Irina; School of Medical Sciences: Brain & Mind Research Institute; Northern Clinical School: AnaesthesiaChemical Synthesis and Structure of the Prokineticin Bv8, ChemBioChem: a European journal of chemical biology, vol.11, 13,pp 1882-1888
2002Conformations of platypus venom C-type natriuretic peptide in aqueous solution and sodium dodecyl sulfate micellesGallagher, Clifford; Kuchel, Philip; Torres, Allan; Alewood, Dianne; Alewood, Paul F; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienConformations of platypus venom C-type natriuretic peptide in aqueous solution and sodium dodecyl sulfate micelles, Toxicon, vol.40,(6),2002,pp 711-719
2005D-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties.Kuchel, Philip; Torres, Allan; Tsampazi, Chryssanthi; Alewood, Paul F; Bansal, Paramjit S; Geraghty, Dominic P; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienD-amino acid residue in a defensin-like peptide from platypus venom: effect on structure and chromatographic properties., Biochemical Journal, vol.391,(Pt 2),2005,pp 215-220
2002D-Amino acid residue in the C-type natriuretic peptide from the venom of the mammal, Ornithorhynchus anatinus, the Australian platypusGallagher, Clifford; Kuchel, Philip; Menz, Robert; Torres, Allan; Alewood, Paul F; Bansal, Paramjit S; Lahnstein, Jelle; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienD-Amino acid residue in the C-type natriuretic peptide from the venom of the mammal, Ornithorhynchus anatinus, the Australian platypus, FEBS Letters, vol.524,(1-3),2002,pp 172-176
2012Intrathecal a-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic painChristie, MacDonald; Klimis, Harry; Napier, Ian; Rycroft, Beth; Adams, David J; Alewood, Paul F; Jin, A; Motin, L; School of Medical Sciences: Pharmacology; Northern Clinical School: Kolling Institute; School of Medical Sciences: Pharmacology; Northern Clinical School: MedicineIntrathecal a-conotoxins Vc1.1, AuIB and MII acting on distinct nicotinic receptor subtypes reverse signs of neuropathic pain, Neuropharmacology, vol.62, 7, 2012,pp 2202-2207
2006Mammalian L-to-D-amino-acid-residue isomerase from platypus venomBelov, Katherine; Kennett, Eleanor; Kuchel, Philip; Torres, Allan; Tsampazi, Chryssanthi; Tsampazi, Maria; Alewood, Paul F; Bansal, Paramjit S; Geraghty, Dominic P; Vet Science Faculty; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienMammalian L-to-D-amino-acid-residue isomerase from platypus venom, FEBS Letters (2005), vol.580,(6),2006,pp 1587-1591
2014MrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptorsChristie, MacDonald; Murali, Swetha Srinivasa; Abraham, Nikita; Alewood, Paul F; Dutertre, Sebastien; Emidio, Nayara; Inserra, Marco; Jin, A; Lewis, Richard J.; Vetter, Irina; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyMrIC, a novel α-conotoxin agonist in the presence of PNU at endogenous α7 nicotinic acetylcholine receptors, Biochemistry, vol.53, 1, 2014,pp 1-3
2005NMR studies of exchange between intra- and extracellular glutathione in human erythrocytesBubb, William (Bill); Kennett, Eleanor; Kuchel, Philip; Alewood, Paul F; Bansal, Paramjit S; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceNMR studies of exchange between intra- and extracellular glutathione in human erythrocytes, Redox Report (Print Edition), vol.10,(2),2005,pp 83-90
2013Novel [omega]-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administrationChristie, MacDonald; Mohammadi, Sarasa; Murali, Swetha; Sadeghi, Mahsa; Alewood, Paul F; Lewis, Richard; School of Medical Sciences: Pharmacology; Northern Clinical School: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyNovel [omega]-conotoxins from C. catus reverse signs of mouse inflammatory pain after systemic administration, Molecular Pain, vol.9, 1, 2013,pp 1-9
2007S100A12 provokes mast cell activation: A potential amplification pathway in asthma and innate immunityHughes, Margaret; Alewood, Paul F; Armishaw, Chris; Cai, Hong; Di Girolamo, Nick; Geczy, Carolyn; Gibson, Peter G.; Hampartzoumian, Taline; Hart, Prue; Hunt, John; Perry, Michael; Simpson, Jodie L; Tedla, Nicodemus; Wang, Hong Wei; Yan, Wei Xing; Yang, Zheng; PharmacyS100A12 provokes mast cell activation: A potential amplification pathway in asthma and innate immunity, Journal of Allergy and Clinical Immunology, vol.119,(1),2007,pp 106-114
2003Solution structure of CnErgl (Ergtoxin), a HERG specific scorpion toxinKuchel, Philip; Torres, Allan; Alewood, Paul F; Bansal, Paramjit S; Bursill, Jane A; Vandenberg, Jamie I; Molecular & Microbial Bioscien; Molecular & Microbial BioscienSolution structure of CnErgl (Ergtoxin), a HERG specific scorpion toxin, FEBS Letters, vol.539,(1-3),2003,pp 138-142
2003Structure of the HERG K+ channel S5P extracellular linker. Role of an amphipathic alpha-Helix in C-type inactivationKuchel, Philip; Sunde, Margaret; Torres, Allan; Alewood, Paul F; Bansal, Paramjit S; Bauskin, Asne R; Breit, Samuel N; Bursill, Jane A; Campbell, Terence J; Clarke, Catherine E; Smith, David J; Vandenberg, Jamie I; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Molecular & Microbial BioscienStructure of the HERG K+ channel S5P extracellular linker. Role of an amphipathic alpha-Helix in C-type inactivation, Journal of Biological Chemistry, vol.278,(43),2003,pp 42136-42148
2009Structure of the pore-helix of the hERG K(+) channelKuchel, Philip; Pages, Guilhem; Vandenberg, Jamie; Alewood, Paul F; Bansal, Paramjit S.; Ju, Pengchu; Torres, Allan M.; School of Molecular Bioscience; School of Molecular Bioscience; School of Molecular BioscienceStructure of the pore-helix of the hERG K(+) channel, European Biophysics Journal, vol.39,(1),2009,pp 111-120
2017The tarantula toxin (Beta)/(delta)-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivityChristie, MacDonald; Mozar, Christine; Murali, Swetha Srinivasa; Vaughan, Christopher; Adams, D; Alewood, Paul F; Bosmans, F; Chin, Y; Cristofori-Armstrong, B; Durek, T; Gilchrist, J; Lewis, Richard; Mobli, Mehdi; Rash, Lachlan D.; Ussing, C; Wingerd, Joshua; School of Medical Sciences: Pharmacology; Northern Clinical School: NCS Office; School of Medical Sciences: Pharmacology; Northern Clinical School: MedicineThe tarantula toxin (Beta)/(delta)-TRTX-Pre1a highlights the importance of the S1-S2 voltage-sensor region for sodium channel subtype selectivity, Scientific Reports, vol.7, 1, 2017,pp 1-15
2011Total Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-assisted FoldingChristie, MacDonald; Moretta, Melissa; Adams, D. J.; Alewood, Paul F; Callaghan, B; Craik, D J; Daly, Norelle L.; de Araujo, Aline; Hopping, Gene; Nevin, S T; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: OfficeTotal Synthesis of the Analgesic Conotoxin MrVIB through Selenocysteine-assisted Folding, Angewandte Chemie (International Edition), vol.50, 29, 2011,pp 6527-6529
2013Vicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine TransporterChristie, MacDonald; Sadeghi, Mahsa; Alewood, Paul F; Brust, Andreas; Daly, Norelle L.; Kennerly, Joe; Lewis, Richard J.; Mobli, Mehdi; Wang, Ching-I A; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyVicinal Disulfide Constrained Cyclic Peptidomimetics: a Turn Mimetic Scaffold Targeting the Norepinephrine Transporter, Angewandte Chemie (International Edition), vol.52, 46, 2013,pp 12020-12023