Browsing by Author Truscott, Roger

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Issue DateTitleAuthor(s)Citation
2007Novel human lens metabolites from normal and cataractous human lensesDavies, Michael; Hains, Peter; Truscott, Roger; Jamie, Joanne F.; Kalinowski, Danuta; Mizdrak, Jasminka; Central Clinical School: Heart Research Institute; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthNovel human lens metabolites from normal and cataractous human lenses, Tetrahedron, vol.63,(23),2007,pp 4990-4999
2003The photosensitiser xanthurenic acid is not present in normal human lensesTruscott, Roger; Gao, L; Hains, P; Central Clinical School: Clinical Ophthal & Eye HealthThe photosensitiser xanthurenic acid is not present in normal human lenses, Experimental Eye Research, vol.77,(5),2003,pp 547-553
2007Post-Translational Modifications in the Nuclear Region of Young, Aged, and Cataract Human LensesHains, Peter; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthPost-Translational Modifications in the Nuclear Region of Young, Aged, and Cataract Human Lenses, Journal Of Proteome Research, vol.6,(10),2007,pp 3935-3943
2010Presbyopia and Cataract: A question of Heat and TimeTruscott, Roger; Zhu, Xiangjia; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Save Sight & Eye Health Inst.Presbyopia and Cataract: A question of Heat and Time, Progress in Retinal and Eye Research, vol.29, 6,pp 487-499
2007Presbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibilityFriedrich, Michael; Heys, Karl; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthPresbyopia and heat: changes associated with aging of the human lens suggest a functional role for the small heat shock protein, alpha-crystallin, in maintaining lens flexibility, Aging Cell, vol.6,(6),2007,pp 807-815
2006Presbyopia: the first stage of nuclear cataract?Truscott, Roger; McGinty, S.J.; Central Clinical School: Clinical Ophthal & Eye HealthPresbyopia: the first stage of nuclear cataract?, Ophthalmic research, vol.38,(3),2006,pp 137-148
2007Protein-bound and free UV filters in cataract lenses. The concentration of UV filters is much lower than in normal lensesKorlimbinis, Anastasia; Truscott, Roger; Aquilina, J Andrew; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthProtein-bound and free UV filters in cataract lenses. The concentration of UV filters is much lower than in normal lenses, Experimental Eye Research, vol.85,(2),2007,pp 219-225
2004Protein-Bound Kynurenine Decreases With The Progression Of Age-Related Nuclear Cataract.Truscott, Roger; Parker, Nicole R.; Sheil, Margaret M.; Vazquez, Santiago; Central Clinical School: Clinical Ophthal & Eye HealthProtein-Bound Kynurenine Decreases With The Progression Of Age-Related Nuclear Cataract., Investigative Ophthalmology and Visual Science (IOVS), vol.45,(3),2004,pp 879-883
2004Protein-Bound Kynurenine Is A Photosensitizer Of Oxidative Damage.Davies, Michael; Jamie, Joanne; Truscott, Roger; Parker, Nicole R.; Central Clinical School: Heart Research Institute; Science Faculty Admin; Central Clinical School: Clinical Ophthal & Eye HealthProtein-Bound Kynurenine Is A Photosensitizer Of Oxidative Damage., Free radical biology & medicine, vol.37,(9),2004,pp 1479-1489
2007Protein-bound UV filters in normal human lenses: the concentration of bound UV filters equals that of free UV filters in the center of older lensesKorlimbinis, Anastasia; Truscott, Roger; Aquilina, J Andrew; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthProtein-bound UV filters in normal human lenses: the concentration of bound UV filters equals that of free UV filters in the center of older lenses, Investigative Ophthalmology & Visual Science, vol.48,(4),2007,pp 1718-1723
2012Racemization of Two Proteins over Our Lifespan: Deamidation of Asparagine 76 in yS Crystallin Is Greater in Cataract than in Normal Lenses across the Age RangeHooi, Michelle; Truscott, Roger; Raftery, Mark J.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthRacemization of Two Proteins over Our Lifespan: Deamidation of Asparagine 76 in yS Crystallin Is Greater in Cataract than in Normal Lenses across the Age Range, Investigative Ophthalmology and Visual Science, vol.53, 7, 2012,pp 3554-3561
2004Regulation Of Tissue Oxygen Levels In The Mammalian Lens.Truscott, Roger; Bassnett, Steven; Mathias, Richard T.; McNulty, Richard; Ortwerth, Beryl J.; Wang, Huan; Central Clinical School: Clinical Ophthal & Eye HealthRegulation Of Tissue Oxygen Levels In The Mammalian Lens., Journal of Physiology, vol.559,(3),2004,pp 883-898
2007Reversible binding of kynurenine to lens proteins: potential protection by glutathione in young lensesKorlimbinis, Anastasia; Parker, Nicole; Truscott, Roger; Davies, Michael J.; Jamie, Joanne F.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Medicine; Central Clinical School: Clinical Ophthal & Eye HealthReversible binding of kynurenine to lens proteins: potential protection by glutathione in young lenses, Investigative Ophthalmology & Visual Science, vol.48,(8),2007,pp 3705-3713
2010Sphingolipid distribution changes with age in the human lensFriedrich, Michael; Truscott, Roger; Blanksby, Stephen J; Deeley, Jane M; Hankin, Joseph; Mitchell, Todd W; Murphy, Robert; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthSphingolipid distribution changes with age in the human lens, Journal of Lipid Research, vol.51, N/A,pp 2753-2760
2016Spontaneous cleavage of proteins at serine and threonine is facilitated by zincKwan, Ann; Lyons, Brian; Truscott, Roger; Molecular Bioscience; Central Clinical School: Save Sight & Eye Health Inst.Spontaneous cleavage of proteins at serine and threonine is facilitated by zinc, Aging Cell, vol.15, 2, 2016,pp 237-244
2011Truncation, cross-linking and interaction of crystallins and intermediate filament proteins in the aging human lensSu, Shih-Ping; Truscott, Roger; Aquilina, J Andrew; McArthur, Jason D.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthTruncation, cross-linking and interaction of crystallins and intermediate filament proteins in the aging human lens, BBA - Proteins and Proteomics, vol.1814, 5, 2011,pp 647-656
2007Tryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damageDavies, Michael; Hains, Peter; Truscott, Roger; Jamie, Joanne F.; Mizdrak, Jasminka; Central Clinical School: Heart Research Institute; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthTryptophan-derived ultraviolet filter compounds covalently bound to lens proteins are photosensitizers of oxidative damage, Free Radical Biology & Medicine (2005), vol.44,(6),2007,pp 1108-1119
2006UV filters in the lens of the thirteen lined ground squirrel (Spermophilus tridecemlineatus).Hains, Peter; Truscott, Roger; Giblin, F.; Simpanya, M.F.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthUV filters in the lens of the thirteen lined ground squirrel (Spermophilus tridecemlineatus)., Experimental Eye Research, vol.82,(4),2006,pp 730-737