Browsing by Author Sahni, Sumit

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Issue DateTitleAuthor(s)Citation
2014Molecular Functions of the Iron-Regulated Metastasis Suppressor, NDRG1, and its Potential as a Molecular Target for Cancer TherapyFang, Bernard; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Park, Kyung Chan; Richardson, Desi (Des); Sahni, Sumit; Central Clinical School: Medicine; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineMolecular Functions of the Iron-Regulated Metastasis Suppressor, NDRG1, and its Potential as a Molecular Target for Cancer Therapy, Biochimica et Biophysica Acta (Molecular and Cell Biology of Lipids), vol.1845, 1, 2014,pp 1-19
2016A Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide CytotoxicityJansson, Patric; Kovacevic, Zaklina; Lok, Hiu; Richardson, Desi (Des); Sahni, Sumit; Hawkins, Clare L.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyA Nitric Oxide Storage and Transport System That Protects Activated Macrophages from Endogenous Nitric Oxide Cytotoxicity, Journal of Biological Chemistry, vol.291, 53, 2016,pp 27042-27061
2017A novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's diseaseAnjum, Rukhsana; Hibbs, David; Kalinowski, Danuta; Lin, Hsuan-Yu Jennifer; Palanimuthu, Duraippandi; Poon, Rachal; Richardson, Desi (Des); Sahni, Sumit; Bernhardt, Paul V; School of Medical Sciences: Pathology; Pharmacy; School of Medical Sciences: Pathology; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyA novel class of thiosemicarbazones show multi-functional activity for the treatment of Alzheimer's disease, European Journal of Medicinal Chemistry, vol.139, N/A, 2017,pp 612-632
2015Novel Thiosemicarbazones Regulate the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway: Inhibition of Constitutive and Interleukin 6-Induced Activation by Iron Depletion.Kalinowski, Danuta; Kovacevic, Zaklina; Lui, Goldie Yuan Lam; Menezes, Sharleen; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineNovel Thiosemicarbazones Regulate the Signal Transducer and Activator of Transcription 3 (STAT3) Pathway: Inhibition of Constitutive and Interleukin 6-Induced Activation by Iron Depletion., Molecular Pharmacology, vol.87, 3, 2015,pp 543-560
2013P-Glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal SequestrationArvind, Akanksha; Jansson, Patric; Richardson, Desi (Des); Sahni, Sumit; Sharp, Danae; Yamagishi, Tetsuo; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Medicine; Central Clinical School: Medicine; School of Medical Sciences: School of Medical SciencesP-Glycoprotein Mediates Drug Resistance via a Novel Mechanism Involving Lysosomal Sequestration, The Journal of Biological Chemistry, vol.288, 44, 2013,pp 31761-31771
2015Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cellsDoddareddy, Munikumar; Fordham, Ashleigh; Hibbs, David; Huang, Michael; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Ong, Jennifer; Pantarat, Namfon; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Bosch Institute; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Pharmacy; Western Clinical School: Westmead Institute for Medical Res; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyPotentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells, Oncotarget, vol.6, 12, 2015,pp 10374-10398
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2015The proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1Bae, Dong-Hun; Huang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Liu, Wensheng; Lui, Goldie Yuan Lam; Merlot, Angelica; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyThe proto-oncogene c-Src and its downstream signaling pathways are inhibited by the metastasis suppressor, NDRG1, Oncotarget, vol.6, 11, 2015,pp 8851-8874
2016Redox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeuticsHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desmond; Sahni, Sumit; Stefani, Christian; Anderson, Gregory; Chua, Anita; Ganz, Tomas; Lee, C Soon; Olynyk, John K; Subramaniam, Nathan; Toyokuni, Shinya; Trinder, Debbie; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyRedox cycling metals: Pedaling their roles in metabolism and their use in the development of novel therapeutics, Biochimica et Biophysica Acta, vol.1863, 4, 2016,pp 727-748
2015The renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazonesFouani, Leyla; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Merlot, Angelica; Richardson, Desi (Des); Sahni, Sumit; Seebacher, Nicole; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; Medicine; Biological SciencesThe renaissance of polypharmacology in the development of anti-cancer therapeutics: Inhibition of the "Triad of Death" in cancer by Di-2-pyridylketone thiosemicarbazones, Pharmacological Research, vol.100, N/A, 2015,pp 255-260
2016Roads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signalingHuang, Michael; Jansson, Patric; Kalinowski, Danuta; Kovacevic, Zaklina; Lane, Darius John Rowland; Lok, Hiu; Merlot, Angelica; Paluncic, Jasmina; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Biomedical Sciences; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyRoads to melanoma: Key pathways and emerging players in melanoma progression and oncogenic signaling, Biochimica et Biophysica Acta, vol.1863, 4, 2016,pp 770-784
2013The role of NDRG1 in the pathology and potential treatment of human cancersBae, Dong-Hun; Huang, Michael; Jansson, Jan (Patric); Kalinowski, Danuta; Kovacevic, Zaklina; Lee, C Soon; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; MedicineThe role of NDRG1 in the pathology and potential treatment of human cancers, Journal of Clinical Pathology, vol.66, 11, 2013,pp 911-917
2016Targeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin SignalingHuang, Michael; Kovacevic, Zaklina; Menezes, Sharleen; Park, Kyung Chan; Richardson, Desi (Des); Sahni, Sumit; Wangpu, Xiongzhi; Xi, Ruxing; Lu, Jiaoyang; Yue, Fei; Zheng, Minhua; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Central Clinical School: Pathology; Northern Clinical School: PathologyTargeting the Metastasis Suppressor, N-Myc Downstream Regulated Gene-1, with Novel Di-2-Pyridylketone Thiosemicarbazones: Suppression of Tumor Cell Migration and Cell-Collagen Adhesion by Inhibiting Focal Adhesion Kinase/Paxillin Signaling, Molecular Pharmacology, vol.89, 5, 2016,pp 521-540
2015The use of iron chelators in biocidal compositions: evaluation of patent, WO2014059417A1Krishan, Sukriti; Palanimuthu, Duraippandi; Richardson, Desi (Des); Sahni, Sumit; School of Medical Sciences: Bosch Institute; Central Clinical School: Pathology; School of Medical Sciences: Pathology; MedicineThe use of iron chelators in biocidal compositions: evaluation of patent, WO2014059417A1, Expert Opinion on Therapeutic Patents, vol.25, 3, 2015,pp 367-372