Browsing by Author Rutledge, Peter

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Issue DateTitleAuthor(s)Citation
2011The crystal structure of isopenicillin N synthase with delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-methionine reveals thioether coordination to ironRutledge, Peter; Adlington, Robert M; Baldwin, Jack E; Clifton, Ian J; Ge, Wei; ChemistryThe crystal structure of isopenicillin N synthase with delta-(L-alpha-aminoadipoyl)-L-cysteinyl-D-methionine reveals thioether coordination to iron, Archives of Biochemistry and Biophysics, vol.516, 2, 2011,pp 103-107
2010Crystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthaseRutledge, Peter; Adlington, Robert M; Baldwin, Jack E; Clifton, Ian J; Ge, Wei; Stok, Jeanette E; ChemistryCrystallographic studies on the binding of selectively deuterated LLD- and LLL-substrate epimers by isopenicillin N synthase, Biochemical and Biophysical Research Communications, vol.398, 4,pp 659-664
2007A cyclobutanone analogue mimics penicillin in binding to isopenicillin N synthaseRutledge, Peter; Adlington, Robert M; Baldwin, Jack E; Clifton, Ian J; Stewart, Amanda C; ChemistryA cyclobutanone analogue mimics penicillin in binding to isopenicillin N synthase, ChemBioChem: a European journal of chemical biology, vol.8,(16),2007,pp 2003-2007
2017Cyclobutanone analogues of (beta)-lactam antibiotics: (beta)-lactamase inhibitors with untapped potential?Devi, Prarthana; Rutledge, Peter; Chemistry; ChemistryCyclobutanone analogues of (beta)-lactam antibiotics: (beta)-lactamase inhibitors with untapped potential?, ChemBioChem, vol.18, 4, 2017,pp 338-351
2010Design and synthesis of a tetradentate '3-amine-1-carboxylate' ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active siteDungan, Victoria; Rutledge, Peter; Mueller-Bunz, Helge; Ortin, Yannick; Chemistry; ChemistryDesign and synthesis of a tetradentate '3-amine-1-carboxylate' ligand to mimic the metal binding environment at the non-heme iron(II) oxidase active site, Organic and Biomolecular Chemistry, vol.8, 7, 2010,pp 1666-1673
2012Diketoacid Inhibitors of HIV-1 Integrase: From L-708,906 to Raltegravir and BeyondBeare, Kaitlin; Rutledge, Peter; Coster, Mark J; Chemistry; ChemistryDiketoacid Inhibitors of HIV-1 Integrase: From L-708,906 to Raltegravir and Beyond, Current Medicinal Chemistry, vol.19, 8, 2012,pp 1177-1192
2016A direct method for the N-tetraalkylation of azamacrocyclesCounsell, Andrew; Jones, Angus; Rutledge, Peter; Todd, Matthew; Chemistry; Chemistry; Chemistry; ChemistryA direct method for the N-tetraalkylation of azamacrocycles, Beilstein Journal of Organic Chemistry, vol.12, N/A, 2016,pp 2457-2461
2015Discovery of microbial natural products by activation of silent biosynthetic gene clustersRutledge, Peter; Challis, Gregory L.; ChemistryDiscovery of microbial natural products by activation of silent biosynthetic gene clusters, Nature Reviews Microbiology, vol.13, 8, 2015,pp 509-523
2015Discovery of microbial natural products by activation of silent biosynthetic gene clustersRutledge, Peter; Challis, Gregory L.; ChemistryDiscovery of microbial natural products by activation of silent biosynthetic gene clusters, Nature Reviews Microbiology, vol.13, 8, 2015,pp 509-523
2015Early Warning Smartphone Diagnostics for Water Security and Analysis Using Real-Time pH MappingAst, Sandra; Canning, John; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Electrical Engineering; ChemistryEarly Warning Smartphone Diagnostics for Water Security and Analysis Using Real-Time pH Mapping, Photonic Sensors, vol.5, 4, 2015,pp 289-297
2015Efficient deprotection of F-BODIPY derivatives: removal of BF2 using Bronsted acidsRutledge, Peter; Tang, Cyril; Todd, Matthew; Turner, Peter; Wong, Joseph Kwun-Hoi; Yu, Mingfeng; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryEfficient deprotection of F-BODIPY derivatives: removal of BF2 using Bronsted acids, Beilstein Journal of Organic Chemistry, vol.11, N/A, 2015,pp 37-41
2013A Fluorescent "Allosteric Scorpionand" Complex Visualizes a Biological Recognition EventRutledge, Peter; Todd, Matthew; Yu, Mingfeng; Yu, Qun; Chemistry; Chemistry; Chemistry; ChemistryA Fluorescent "Allosteric Scorpionand" Complex Visualizes a Biological Recognition Event, ChemBioChem: a European journal of chemical biology, vol.14, 2, 2013,pp 224-229
2015Fluorescent measurements of Zn2+ on a smartphoneAst, Sandra; Canning, John; Cook, Kevin; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Chemistry; Electrical Engineering; ChemistryFluorescent measurements of Zn2+ on a smartphone, Proceedings of SPIE, vol.9655, 2015, pp. 1-4
2015Fluorescent measurements of Zn2+ on a smartphoneAst, Sandra; Canning, John; Cook, Kevin; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Electrical and Information Engineering; Electrical and Information Engineering; ChemistryFluorescent measurements of Zn2+ on a smartphone, Fifth Asia-Pacific Optical Sensors Conference Proceedings of SPIE volume 9655, vol.9655, 2015, pp. 1-4
2015Fluorescent measurements of Zn2+ on a smartphoneAst, Sandra; Canning, John; Cook, Kevin; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Electrical and Information Engineering; Electrical and Information Engineering; ChemistryFluorescent measurements of Zn2+ on a smartphone, Fifth Asia-Pacific Optical Sensors Conference Proceedings of SPIE volume 9655, vol.9655, 2015, pp. 1-4
2015Fluorescent measurements of Zn2+ on a smartphoneAst, Sandra; Canning, John; Cook, Kevin; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Electrical and Information Engineering; Electrical and Information Engineering; ChemistryFluorescent measurements of Zn2+ on a smartphone, Fifth Asia-Pacific Optical Sensors Conference Proceedings of SPIE volume 9655, vol.9655, 2015, pp. 1-4
2015Fluorescent measurements of Zn2+ on a smartphoneAst, Sandra; Canning, John; Cook, Kevin; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Electrical and Information Engineering; Electrical and Information Engineering; ChemistryFluorescent measurements of Zn2+ on a smartphone, Fifth Asia-Pacific Optical Sensors Conference Proceedings of SPIE volume 9655, vol.9655, 2015, pp. 1-4
2015Fluorescent measurements of Zn2+ on a smartphoneAst, Sandra; Canning, John; Cook, Kevin; Hossain, Md Arafat; Jamalipour, Abbas; Rutledge, Peter; Chemistry; Chemistry; Chemistry; Electrical and Information Engineering; Electrical and Information Engineering; ChemistryFluorescent measurements of Zn2+ on a smartphone, Fifth Asia-Pacific Optical Sensors Conference Proceedings of SPIE volume 9655, vol.9655, 2015, pp. 1-4
2014Incorporating a piperidinyl group in the fluorophore extends the fluorescence lifetime of click-derived cyclam-naphthalimide conjugatesAst, Sandra; Lo, Anthony; Rutledge, Peter; Todd, Matthew; Yu, Mingfeng; Yu, Qun; Flehr, Roman; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryIncorporating a piperidinyl group in the fluorophore extends the fluorescence lifetime of click-derived cyclam-naphthalimide conjugates, PLoS One, vol.9, 7, 2014,pp e100761-1-e100761-12
2013Incorporation of bulky and cationic cyclam-triazole moieties into marimastat can generate potent MMP inhibitory activity without inducing cytotoxicityEllis, Samantha; Rutledge, Peter; Todd, Matthew; Triccas, James; Yu, Mingfeng; Lim, Ngee H.; Nagase, Hideaki; Central Clinical School: Medicine; Chemistry; Chemistry; Central Clinical School: Medicine; ChemistryIncorporation of bulky and cationic cyclam-triazole moieties into marimastat can generate potent MMP inhibitory activity without inducing cytotoxicity, ChemistryOpen, vol.2, 3, 2013,pp 99-105