Browsing by Author Liddle, Christopher

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Issue DateTitleAuthor(s)Citation
2016Dose escalation of tamoxifen in patients with low endoxifen level: Evidence for therapeutic drug monitoring - The TADE studyBalleine, Rosemary; Gao, Bo-Fu; Gebski, Val; Gurney, Howard; Hui, Rina; Kefford, Richard (Rick); Lee, Clara; Liddle, Christopher; Menzies, Alexander Maxwel; Provan, Pamela; Wilcken, Nicholas; Wong, Ka (Mark); Ali, Sayed Sahanawaz; Balakrishnar, Bavanthi; Coulter, Sally A.; Fox, Peter; Lynch, Jodi; Yeap, Shang Heng; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; NH&MRC Clinical Trials Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Western Clinical School (Westmead): Office; Western Clinical School: Medicine (Westmead); Central Clinical School: Medicine; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead)Dose escalation of tamoxifen in patients with low endoxifen level: Evidence for therapeutic drug monitoring - The TADE study, Clinical Cancer Research, vol.22, 13, 2016,pp 3164-3171
2017Dose individualization of sunitinib in metastatic renal cell cancer: toxicity-adjusted dose or therapeutic drug monitoringGebski, Val; Liddle, Christopher; Balakrishnar, Bavanthi; Chan, Mathew; Coulter, Sally A.; Fox, Peter; Gurney, Howard; Sabanathan, Dhanusha; Zhang, Alison; NH&MRC Clinical Trials Centre; Westmead Clinical School: MedicineDose individualization of sunitinib in metastatic renal cell cancer: toxicity-adjusted dose or therapeutic drug monitoring, Cancer Chemotherapy and Pharmacology, vol.80, 2, 2017,pp 385-393
2008Downregulation of drug transport and metabolism in mice bearing extra-hepatic malignanciesClarke, Stephen; Kacevska, Marina; Liddle, Christopher; London, Roslyn; Robertson, Graham; Sharma, Rohini; Northern Clinical School: Kolling Institute; Pharmacy; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Concord Clinical School: ANZAC Research Institute; Western Clinical School: Westmead Millennium InstituteDownregulation of drug transport and metabolism in mice bearing extra-hepatic malignancies, British Journal of Cancer, vol.98, 1, 2008,pp 91-97
2002Drugs and the liver updated, 2002Farrell, Geoffrey; Liddle, Christopher; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Drugs and the liver updated, 2002, Seminars in Liver Disease, vol.22,(2),2002,pp 109-113
2003Effectiveness of interferon alfa-2b/ribavirin combination therapy for chronic hapatitis c in a clinic settingFarrell, Geoffrey; George, Jacob; Kumar, Divesh; Liddle, Christopher; Lin, Rita; Samarasinghe, Dev; Wallington-Beddoe, C; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); MedicineEffectiveness of interferon alfa-2b/ribavirin combination therapy for chronic hapatitis c in a clinic setting, Medical Journal of Australia, vol.178,(6),2003,pp 267-271
2004Effects Of Interferon Treatment Response On Liver Complications Of Chronic Hepatitis C: 9-Year Follow-Up Study.Farrell, Geoffrey; George, Jacob; Liddle, Christopher; Lin, Rita; Samarasinghe, Dev; Weltman, Martin; Byth, Karen; Coverdale, Shirley A.; Crewe, Evelyn; Kench, James G; Khan, Mahbub H.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Nepean Clinical School: MedicineEffects Of Interferon Treatment Response On Liver Complications Of Chronic Hepatitis C: 9-Year Follow-Up Study., American Journal of Gastroenterology, vol.99,(4),2004,pp 636-644
2014Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizerLiddle, Christopher; Ahmadian, Maryam; et al, .; Goetz, Regina; Huang, Zhifeng; Jonker, Johan; Lackey, Denise; Liu, Weilin; Osborn, Olivia; Suh, Jae Myoung; van Dijk, Theo; Yoshihara, Eiji; Western Clinical School: Medicine (Westmead)Endocrinization of FGF1 produces a neomorphic and potent insulin sensitizer, Nature, vol.513, 7518, 2014,pp 436-439
2015ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to PluripotencyLiddle, Christopher; Ecker, Joseph; et al, Various; Jacinto, Sandra; Kawamura, Teruhisa; Kida, Yasuyuki; Kushige, Hiroko; Shigeno, Asako; Sogo, Takahiro; Wei, Zong; Yoshihara, Eiji; Western Clinical School: Medicine (Westmead)ERRs Mediate a Metabolic Switch Required for Somatic Cell Reprogramming to Pluripotency, Cell Stem Cell, vol.16, 5, 2015,pp 547-555
2016ERRY Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive sß CellsLiddle, Christopher; Ahmadian, Maryam; Atkins, Annette; Dai, Yang; Downes, Michael; Evans, Ronald; Fang, Sungsoon; Kida, Yasuyuki; Lin, Chun Shi; Tseng, Tiffany W.; Wei, Zong; Yoshihara, Eiji; Yu, Ruth; Western Clinical School: Medicine (Westmead)ERRY Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive sß Cells, Cell Metabolism, vol.23, 4, 2016,pp 622-634
2016ERRY Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive sß CellsLiddle, Christopher; Ahmadian, Maryam; Atkins, Annette; Dai, Yang; Downes, Michael; Evans, Ronald; Fang, Sungsoon; Kida, Yasuyuki; Lin, Chun Shi; Tseng, Tiffany W.; Wei, Zong; Yoshihara, Eiji; Yu, Ruth; Western Clinical School: Medicine (Westmead)ERRY Is Required for the Metabolic Maturation of Therapeutically Functional Glucose-Responsive sß Cells, Cell Metabolism, vol.23, 4, 2016,pp 622-634
2013Extra-Hepatic Cancer Represses Hepatic Drug Metabolism Via Interleukin (IL)-6 SignallingClarke, Stephen; Kacevska, Marina; Liddle, Christopher; Mahns, Andre; Robertson, Graham; Sharma, Rohini; Northern Clinical School: Kolling Institute; Pharmacy; Western Clinical School: Medicine (Westmead); Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Western Clinical School: Westmead Millennium InstituteExtra-Hepatic Cancer Represses Hepatic Drug Metabolism Via Interleukin (IL)-6 Signalling, Pharmaceutical Research, vol.30, 9, 2013,pp 2270-2278
2011Extrahepatic Cancer Suppresses Nuclear Receptor–Regulated Drug MetabolismClarke, Stephen; Kacevska, Marina; Liddle, Christopher; Robertson, Graham; Sharma, Rohini; Downes, Michael; Evans, Ronald; Concord Clinical School: ANZAC Research Institute; Pharmacy; Western Clinical School: Medicine (Westmead); Concord Clinical School: ANZAC Research Institute; Western Clinical School: Westmead Millennium InstituteExtrahepatic Cancer Suppresses Nuclear Receptor–Regulated Drug Metabolism, Clinical Cancer Research, vol.17, 10, 2011,pp 3170-3180
2004Feed-Forward Regulation Of Bile Acid Detoxification By Cyp3A4: Studies In Humanized Transgenic MiceCoulter, Sally; Liddle, Christopher; Robertson, Graham; Stedman, Catherine; School of Medical Sciences: Pharmacology; Western Clinical School: Medicine (Westmead); Concord Clinical School: ANZAC Research Institute; Clinical SchoolsFeed-Forward Regulation Of Bile Acid Detoxification By Cyp3A4: Studies In Humanized Transgenic Mice, Journal of Biological Chemistry, vol.279,(12),2004,pp 11336-11346
2011FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathwaysCoulter, Sally; Liddle, Christopher; Eastham-Anderson, Jeffrey; French, Dorothy; Peterson, Andrew; Sonoda, Junichiro; Wong, Anne; Wu, Ai-Luen; School of Medical Sciences: Pharmacology; Western Clinical School: Medicine (Westmead)FGF19 regulates cell proliferation, glucose and bile acid metabolism via FGFR4-dependent and independent pathways, PLoS One, vol.6, 3, 2011,pp 1-11
2016FibroGENE: A gene-based model for staging liver fibrosisAhlenstiel, Golo; Booth, David; Douglas, Mark; Eslam, Mohammed; George, Jacob; Kelaeng, Kebitsaone; Liddle, Christopher; Weltman, Martin; Abate, Maria; Adams, Leon Anton; Berg, Thomas; Chan, Henry Lik Yuen; Dore, Gregory; et al, Various; Hashem, Ahmed M; Irving, William; Mangia, Alessandra; Romero-Gomez, Manuel; Sheridan, David; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead); Nepean Clinical School: MedicineFibroGENE: A gene-based model for staging liver fibrosis, Journal of Hepatology, vol.64, 2, 2016,pp 390-398
2012FXR and PXR: Potential therapeutic targets in cholestasisLiddle, Christopher; Downes, Michael; Jonker, Johan; Western Clinical School: Medicine (Westmead)FXR and PXR: Potential therapeutic targets in cholestasis, Journal of Steroid Biochemistry and Molecular Biology, vol.130, 3-5, 2012,pp 147-158
2002Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infectionFarrell, Geoffrey; George, Jacob; Hui, Jason; Liddle, Christopher; Lin, Rita; Samarasinghe, Dev; Byth, Karen; Kench, James; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Clinical Schools; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead)Genotype-specific mechanisms for hepatic steatosis in chronic hepatitis C infection, Journal of Gastroenterology and Hepatology, vol.17,(8),2002,pp 873-881
2003Growth hormone modulation of the rat hepatic bile transporter system in endotoxin-induced cholestasisBaxter, Robert; Coulter, Sally; Delhanty, Patrick; Liddle, Christopher; McDougall, Fiona; Mesotten, D; Van den Berghe, Greet; Northern Clinical School: Kolling Institute; School of Medical Sciences: Pharmacology; Northern Clinical School: Kolling Institute; Western Clinical School: Medicine (Westmead); Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteGrowth hormone modulation of the rat hepatic bile transporter system in endotoxin-induced cholestasis, Endocrinology, vol.144,(9),2003,pp 4008-4017
2013Hepatic Fat Loss in Advanced Nonalcoholic Steatohepatitis: Are Alterations in Serum Adiponectin the Cause?Coulter, Sally; George, Jacob; Hebbard, Lionel; Kacevska, Marina; Liddle, Christopher; Ramezani-Moghadam, Mehdi; Schrijnders, Dennis; van der Poorten, David; Wu, Lindsay; Bugianesi, Elisabetta; Komuta, Mina; McLeod, Duncan; Roskams, Tania; Samer, Caroline; School of Medical Sciences: Pharmacology; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Pharmacy; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Children's Hospital Westmead: Medicine; ChemistryHepatic Fat Loss in Advanced Nonalcoholic Steatohepatitis: Are Alterations in Serum Adiponectin the Cause?, Hepatology, vol.57, 6, 2013,pp 2180-2188
2014Hepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependentAhlenstiel, Golo; Booth, David; Douglas, Mark; George, Jacob; Leung, Reynold; Liddle, Christopher; O'Connor, Kate; Parnell, Grant; Patrick, Ellis; Read, Scott Andrew; Stewart, Graeme; Suppiah, Vijayaprakash; van der Poorten, David; Yang, Jean Yee Hwa; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Nepean Clinical School: Medicine; Mathematics & Statistics; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Children's Hospital Westmead: Medicine; Mathematics & StatisticsHepatic metallothionein expression in chronic hepatitis C virus infection is IFNL3 genotype-dependent, Genes and Immunity, vol.15, 2, 2014,pp 88-94