Browsing by Author Ittner, Lars

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Issue DateTitleAuthor(s)Citation
2008Divergent phosphorylation pattern of tau in P301L tau transgenic miceDeters, Natasha; Goetz, Jurgen; Ittner, Lars; Molecular & Microbial Bioscien; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesDivergent phosphorylation pattern of tau in P301L tau transgenic mice, European Journal of Neuroscience, vol.28,(1),2008,pp 137-147
2006Do axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?Goetz, Jurgen; Ittner, Lars; Kins, Stefan; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesDo axonal defects in tau and amyloid precursor protein transgenic animals model axonopathy in Alzheimer's disease?, Journal of Neurochemistry, vol.98,(4),2006,pp 993-1006
2015Early-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degenerationIttner, Lars; Kril, Jillian; Sutherland, Greg; Abramowski, Dorothee; Chan, Chesed Kai-Xin; Gladbach, Amadeus; Halliday, G; Hodges, John R.; Ong, Weiyi; Przybyla, Magdalena; Staufenbiel, Matthias; Stefanoska, Kristie; Stevens, Claire; van Eersel, Janet; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Medicine; School of Medical Sciences: PathologyEarly-onset axonal pathology in a novel P301S-Tau transgenic mouse model of frontotemporal lobar degeneration, Neuropathology and Applied Neurobiology, vol.41, 7, 2015,pp 906-925
2014ERK inhibition with PD184161 mitigates brain damage in a mouse model of strokeBi, Mian; Gladbach, Amadeus; Ittner, Lars; Ke, Yazi; Van Eersel, Janet; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: PharmacologyERK inhibition with PD184161 mitigates brain damage in a mouse model of stroke, Journal of Neural Transmission, vol.121, 5, 2014,pp 543-547
2012Evidence for complex binding profiles and species differences at the translocator protein (TSPO) (18 kDa)Ittner, Lars; Kassiou, Michael; Luus, Christopher; Scarf, Alana; Da Pozzo, Eleonora; Guarino, C.; Martini, Claudia; Selleri, Silvia; School of Medical Sciences: Brain and Mind Centre; Chemistry; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyEvidence for complex binding profiles and species differences at the translocator protein (TSPO) (18 kDa), Current Molecular Medicine, vol.12, 4, 2012,pp 488-493
2009Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease.Delerue, Fabien; Gladbach, Amadeus; Goetz, Jurgen; Ittner, Lars; Yazi, K; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteExperimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease., P L o S One, vol.4,(11),2009,pp e7917 - 1-e7917 - 7
2015First demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO)Barron, Melissa; Hanani, Raphy; Kassiou, Michael; King, Victoria; Narlawar, Rajeshwar; Rendina, Louis; Scarf, Alana; Werry, Eryn; Chua, Sook Wern; Ittner, Lars; Martins, Ralph N.; Medical Imaging and Radiation Sciences; Chemistry; Medical Imaging and Radiation Sciences; School of Medical Sciences: Bosch Institute; Pharmacy; Chemistry; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation SciencesFirst demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO), Journal of Medicinal Chemistry, vol.58, 21, 2015,pp 8743-8749
2015First demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO)Barron, Melissa; Hanani, Raphy; Kassiou, Michael; King, Victoria; Narlawar, Rajeshwar; Rendina, Louis; Scarf, Alana; Werry, Eryn; Chua, Sook Wern; Ittner, Lars; Martins, Ralph N.; Medical Imaging and Radiation Sciences; Chemistry; Chemistry; School of Medical Sciences: Bosch Institute; Pharmacy; Chemistry; School of Medical Sciences: Pharmacology; Medical Imaging and Radiation SciencesFirst demonstration of positive allosteric-like modulation at the human wild type translocator protein (TSPO), Journal of Medicinal Chemistry, vol.58, 21, 2015,pp 8743-8749
2016The frontotemporal dementia-motor neuron disease continuumKiernan, Matthew; Kril, Jillian; Burrell, James; Gotz, Jurgen; Halliday, Glenda M.; Hodges, John R.; Ittner, Lars; Central Clinical School: Medicine; Central Clinical School: MedicineThe frontotemporal dementia-motor neuron disease continuum, The Lancet, vol.388, 10047, 2016,pp 919-931
2008Functional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein responseBokhari, Yaa; David, Della; Deters, Natasha; Goetz, Jurgen Martin; Ittner, Lars; Ke, Yazi; Lim, Yun-An; Schonrock, Nicole; Wiesner, Andreas; Fath, Thomas; Hoerndli, Frederic J.; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: School of Medical Sciences; Molecular Bioscience; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: Brain & Mind Research InstituteFunctional genomics dissects pathomechanisms in tauopathies: mitosis failure and unfolded protein response, Neurodegenerative Diseases, vol.5, N/A, 2008,pp 179-181
2010Gateway-compatible lentiviral transfer vectors for ubiquitin promoter driven expression of fluorescent fusion proteinsGoetz, Jurgen Martin; Ittner, Lars; Krupka, Niklas; Strappe, Padraig; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentreGateway-compatible lentiviral transfer vectors for ubiquitin promoter driven expression of fluorescent fusion proteins, Plasmid, vol.63, 3, 2010,pp 155-160
2013Glutamate metabolism is impaired in transgenic mice with tau hyperphosphorylationGoetz, Jurgen; Ittner, Lars; Nilsen, Linn Hege; Rae, Caroline; Sonnewald, Ursula; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteGlutamate metabolism is impaired in transgenic mice with tau hyperphosphorylation, Journal of Cerebral Blood Flow and Metabolism, vol.33, 5, 2013,pp 684-691
2008Human but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical culturesGotz, Jurgen; Ittner, Lars; Lim, Yun Li; Lim, Yun-An; Central Clinical School: Brain & Mind Research Institute; School of Medical Sciences: School of Medical Sciences; Central Clinical School: Brain & Mind Research Institute; Central Clinical School: Brain & Mind Research InstituteHuman but not rat amylin shares neurotoxic properties with Abeta42 in long-term hippocampal and cortical cultures, FEBS Letters, vol.582,(15),2008,pp 2188-2194
2006Impaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice.Goetz, Jurgen; Ittner, Lars; Isenmann, Stefan; Kretz, Alexandra; Ogris, Egon; Schild, Andreas; Seeliger, Mathias W.; Tanimoto, Naoyuki; Tonagel, Felix; Central Clinical School: Brain & Mind Research Institute; School of Medical Sciences: School of Medical SciencesImpaired development of the Harderian gland in mutant protein phosphatase 2A transgenic mice., Mechanisms of Development, vol.123,(5),2006,pp 362-371
2014Inducible, tightly regulated and non-leaky neuronal gene expression in miceDelerue, Fabien; Ittner, Lars; White, Michael; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteInducible, tightly regulated and non-leaky neuronal gene expression in mice, Transgenic Research, vol.23, 2, 2014,pp 225-233
2011Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiolGoetz, Jurgen; Ittner, Lars; Lim, Yun-An; Eckert, Anne; Giese, Maria; Grimm, Amandine; Mensah-Nyagan, Ayikoe Guy; Villafranca, J Ernest; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteInhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol, PLoS One, vol.6, 12, 2011,pp e28887 - 1-e28887 - 12
2011Invertebrate and Vertebrate Models of TauopathiesGoetz, Jurgen Martin; Goetz, Naeman; Ittner, Lars; Lam, Hong Yan; Nicholas, Hannah; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; Biological Sciences; Molecular BioscienceInvertebrate and Vertebrate Models of Tauopathies in Animal Models for Neurodegenerative Disease, RSC Publishing, 2011, pp. 69-85
2008Is tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?Goetz, Jurgen; Ittner, Lars; Schonrock, Nicole; Fandrich, Marcus; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: School of Medical SciencesIs tau aggregation toxic or protective: a sensible question in the absence of sensitive methods?, Journal of Alzheimer's Disease, vol.14,(4),2008,pp 423-429
2012Lessons from Tau-Deficient MiceDe Silva, Dineeka; Hoven, Julia van der; Ittner, Arne; Ittner, Lars; Ke, Yazi; Suchowerska, Alexandra; Van Eersel, Janet; Wu, Christopher; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Pharmacology; School of Medical Sciences: Brain & Mind Research InstituteLessons from Tau-Deficient Mice, International Journal of Alzheimer's Disease, vol.2012, Article ID 873270, 2012,pp 1-8
2011Modes of Aβ toxicity in Alzheimer's disease.Goetz, Jurgen; Ittner, Lars; Liu, Xin; Sanchez Matamales, Miriam; Eckert, Anne; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteModes of Aβ toxicity in Alzheimer's disease., Cellular and Molecular Life Sciences, vol.68, 20, 2011,pp 3359-3375