Browsing by Author Wiley, James

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Issue DateTitleAuthor(s)Citation
2005A 50 intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian populationDao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Skarratt, K; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineA 50 intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian population, FEBS Letters (2005), vol.579,(12),2005,pp 2675-2678
2008Analysis of a large multi-generational family provides insight into the genetics of chronic lymphocytic leukemiaDao-Ung, L; Fuller, Stephen; McKinnon, Leah; Skarratt, K; Wiley, James; Crowther-Swanepoel, Dalemari; Houlston, Richard S.; Papaemmanuil, Elli; Sellick, Gabrielle S; Webb, Emily L.; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineAnalysis of a large multi-generational family provides insight into the genetics of chronic lymphocytic leukemia, British Journal of Haematology, vol.142,(2),2008,pp 238-245
2006Analysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray.Barber, Nicole; Belov, Larissa; Bendall, Linda; Bradstock, Kenneth; Christopherson, Richard; Mulligan, Stephen; Sartor, M; Wiley, James; Young, Graham; Chrisp, Jeremy S; Erber, Wendy; Green, Anthony R; Huang, Pauline; Juneja, Surender; Keating, Michael J; Pascovici, Dana S; Scott, Mike A; Sewell, William A; Stoner, Kerryn; Thomas, Mervyn; Wierda, William G; Woolfson, Adrian; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Molecular & Microbial Bioscien; Molecular & Microbial Bioscien; Western Clinical School: Medicine (Westmead); Nepean Clinical School: Medicine; Central Clinical School: MedicineAnalysis of human leukaemias and lymphomas using extensive immunophenotypes from an antibody microarray., British Journal of Haematology, vol.135,(2),2006,pp 184-97
2004An Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor.Barden, Julian; Dao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Shemon, Anne; Skarratt, K; Sluyter, Ronald; Wiley, James; Clarke, Alison L; Petrou, Steven; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineAn Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor., Journal of Biological Chemistry, vol.279,(30),2004,pp 31287-31295
2003Autoimmune hemolysis associated with primary biliary cirrhosis responding to ursodeoxycholic acid as sole treatmentFuller, Stephen; Kumar, P; Weltman, Martin; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineAutoimmune hemolysis associated with primary biliary cirrhosis responding to ursodeoxycholic acid as sole treatment, American Journal Of Hematology, vol.72,(1),2003,pp 31-33
2007Canine erythrocytes express the P2X7 receptor: greatly increased function compared to human erythrocytesEslick, Guy; Georgiou, Jennifer; Shemon, Anne; Sluyter, Ronald; Stevenson, Ryan; Taylor, Rosanne; Wiley, James; Hughes, William E; School of Public Health: Public Health; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Vet Science Faculty; Nepean Clinical School: MedicineCanine erythrocytes express the P2X7 receptor: greatly increased function compared to human erythrocytes, American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol.293,(5),2007,pp R2090-R2098
2004Chelerythrine And Other Benzophenanthridine Alkaloids Block The Human P2X(7) ReceptorConigrave, Arthur; Shemon, Anne; Sluyter, Ronald; Wiley, James; Molecular & Microbial Bioscien; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineChelerythrine And Other Benzophenanthridine Alkaloids Block The Human P2X(7) Receptor, British Journal of Pharmacology, vol.142,(6),2004,pp 1015-1019
2011Dysregulation of the inflammatory response to the parasite, Toxoplasma gondii, in P2X7 receptor-deficient miceFuller, Stephen; Wiley, James; Boulter, Nicola R.; Ikin, Rowan; Katrib, Marilyn; Lees, Michael P.; Miller, Catherine M.; Smith, Nicholas C.; Zakrzewski, Alana M.; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineDysregulation of the inflammatory response to the parasite, Toxoplasma gondii, in P2X7 receptor-deficient mice, International Journal for Parasitology, vol.41, 3-4, 2011,pp 301-308
2010Evidence for associations between the purinergic receptor P2X7 (P2RX7) and toxoplasmosisFuller, Stephen; Wiley, James; Boulter, Nicola R.; Boyer, Kenneth; Castellucci, Lea; de Roubaix, Lee-Anne; et, al; Guerra Peixe, Ricardo; Hargrave, Aubrey C.; Jamieson, Sarra E.; Miller, E. Nancy; Mui, Ernest J.; Peixoto-Rangel, Alba; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineEvidence for associations between the purinergic receptor P2X7 (P2RX7) and toxoplasmosis, Genes and Immunity, vol.11, 5,pp 374-383
2009Extracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation.McGeachie, A; Stokes, Leanne; Wiley, James; Gu, Ben; Rathsam, Catherine; Children's Hospital Westmead: Childrens Medical Research Ins; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineExtracellular ATP dissociates nonmuscle myosin from P2X(7) complex: this dissociation regulates P2X(7) pore formation., American Journal of Physiology: Cell Physiology, vol.297, 2,pp C430-C439
2004Extracellular ATP Increases Cation Fluxes In Human Erythrocytes By Activation Of The P2X7 ReceptorBarden, Julian; Shemon, Anne; Sluyter, Ronald; Wiley, James; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineExtracellular ATP Increases Cation Fluxes In Human Erythrocytes By Activation Of The P2X7 Receptor, Journal of Biological Chemistry, vol.279,(43),2004,pp 44749-44755
2005Gene Dosage Determines the Negative Effects of Polymorphic Alleles of the P2X7 Receptor on Adenosine Triphosphate–Mediated Killing of Mycobacteria by Human MacrophagesBritton, Warwick; Fernando, Sujatha; Saunders, Bernadette; Skarratt, K; Sluyter, Ronald; Wiley, James; Central Clinical School: Centenary Institute; School of Rural Health: Medicine; Central Clinical School: Centenary Institute; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineGene Dosage Determines the Negative Effects of Polymorphic Alleles of the P2X7 Receptor on Adenosine Triphosphate–Mediated Killing of Mycobacteria by Human Macrophages, The Journal of Infectious Diseases 2005, vol.192,(1),2005,pp 149-155
2007The genetic control of susceptibility to Mycobacterium tuberculosisBritton, Warwick; Fernando, Sujatha; Saunders, Bernadette; Sluyter, Ronald; Wiley, James; Central Clinical School: Centenary Institute; School of Rural Health: Medicine; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineThe genetic control of susceptibility to Mycobacterium tuberculosis in Decoding the Genomic Control of Immune Reactions, John Wiley & Sons, 2007, pp. 79-89; discussion 89-92, 208-9
2009Genetics of the P2X7 receptor and human diseaseFuller, Stephen; Gu, Baijun (Ben); Skarratt, K; Stokes, Leanne; Wiley, James; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineGenetics of the P2X7 receptor and human disease, Purinergic Signalling, vol.5,(2),2009,pp 257-262
2009Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20Booth, David; Stewart, Graeme; Wiley, James; Bahlo, Melanie; Broadley, Simon; Brown, M. A.; et al, various; Foote, Simon J.; Griffiths, L; Kilpatrick, T J; Lechner-Scott, Jeanette; Moscato, Pablo; Perreau, Victoria; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Nepean Clinical School: MedicineGenome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20, Nature Genetics, vol.41, 7,pp 824-830
2004Glu496 To Ala Polymorphism In The P2X7 Receptor Impairs ATP-Induced IL-1 Beta Release From Human Monocytes.Shemon, Anne; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineGlu496 To Ala Polymorphism In The P2X7 Receptor Impairs ATP-Induced IL-1 Beta Release From Human Monocytes., Journal of Immunology, vol.172,(6),2004,pp 3399-3405
2005A high-density SNP genomewide linkage scan for chronic lymphocytic leukemia-susceptibility loci.Fuller, Stephen; Wiley, James; Allinson, Ruth; Callea, Vincenzo; Catovsky, Daniel; Dyer, Martin J S; Houlston, Richard S.; Jonsson, Viggo; Langerak, Anton W.; Lyttelton, Matthew; Matutes, Estella; Mauro, Francesca R; Sellick, Gabrielle S; Webb, Emily L.; Yuille, Martin; Northern Clinical School: Medicine; Nepean Clinical School: MedicineA high-density SNP genomewide linkage scan for chronic lymphocytic leukemia-susceptibility loci., American Journal of Human Genetics, vol.77,(3),2005,pp 420-429
2005Human Epidermal and Monocyte-Derived Langerhans Cells Express Functional P2X7 ReceptorsChristopherson, Richard; Fuller, Stephen; Georgiou, Jennifer; Martin, Christopher; Skarratt, K; Sluyter, Ronald; Wiley, James; Molecular & Microbial Bioscien; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Surgery; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineHuman Epidermal and Monocyte-Derived Langerhans Cells Express Functional P2X7 Receptors, THE JOURNAL OF INVESTIGATIVE DERMATOLOGY 2005, vol.125,(3),2005,pp 482-490
2003An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptorBarden, Julian; Dao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Li, Changping; Shemon, Anne; Sluyter, Ronald; Wiley, James; Petrou, Steven; Smart, Megan L; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineAn Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor, Journal of Biological Chemistry, vol.278,(19),2003,pp 17108-17113
2007Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonistShemon, Anne; Sluyter, Ronald; Stokes, Leanne; Wiley, James; Manley, Paul W; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineInhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist, Biochemical and Biophysical Research Communications (2005), vol.365,(Available online 20 November 2007),2007,pp 515-520