Browsing by Author Vadas, Mathew

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Issue DateTitleAuthor(s)Citation
2013Active subnetwork recovery with a mechanism-dependent scoring function; with application to angiogenesis and organogenesis studiesCaetano, Tiberio; Charleston, Michael; Gamble, Jennifer; Lichtenstein, Ilana; Vadas, Mathew; Schl Information Technologies; Schl Information Technologies; Central Clinical School: Centenary Institute; Schl Information Technologies; Central Clinical School: Centenary InstituteActive subnetwork recovery with a mechanism-dependent scoring function; with application to angiogenesis and organogenesis studies, BMC Bioinformatics, vol.14, 1, 2013,pp 1-22
2013Age-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cellsChang, Garry; Coleman, Paul; Gamble, Jennifer; Grimshaw, Matthew; Hutas Attila, Gabor; Vadas, Mathew; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteAge-associated stresses induce an anti-inflammatory senescent phenotype in endothelial cells, Aging, vol.5, 12, 2013,pp 913-924
2017ARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Pro-Inflammatory Smooth Muscle Cell PhenotypeBannon, Paul; Gamble, Jennifer; Hambly, Brett; Jeremy, Richmond; Liu, Renjing; Robertson, Elizabeth; Vadas, Mathew; Jarrah, Sorour; Lay, Angelina; Li, Haibo; Lo, Lisa; Richmond, David R.; Sherrah, Andrew; Ting, Ka Ka; Zhao, Yang; Zhou, Zhaoxiong; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteARHGAP18 Protects Against Thoracic Aortic Aneurysm Formation by Mitigating the Synthetic and Pro-Inflammatory Smooth Muscle Cell Phenotype, Circulation Research, vol.121, 5, 2017,pp 512-524
2014ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctionsBecker, Thomas; Chang, Garry Hoi-Kai; Coleman, Paul; Formaz-Preston, Ann; Gamble, Jennifer; Jolly, Christopher; Lay, Angelina; Powter, Elizabeth; Rinkwitz, Silke; Ting, Ka Ka; Vadas, Mathew; Zhao, Yang; Bower, Neil; Hogan, Benjamin; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions, Small GTPases, vol.5, 3, 2014,pp 1-15
2008Basal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1Gamble, Jennifer; Vadas, Mathew; Xia, Pu; Bonder, Claudine S; Hahn, Chris; Li, Xiaochun; Parsons, Michelle; Pitson, Stuart; Proia, Richard; Stankovic, Milena; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteBasal and angiopoietin-1-mediated endothelial permeability is regulated by sphingosine kinase-1, Blood, vol.111,(7),2008,pp 3489-3497
2014Beyond Liver Fibrosis: Hepatic Stellate Cell Senescence Links Obesity to Liver Cancer by Way of the MicrobiomeGamble, Jennifer; McCaughan, Geoffrey William; Shackel, Nicholas; Vadas, Mathew; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteBeyond Liver Fibrosis: Hepatic Stellate Cell Senescence Links Obesity to Liver Cancer by Way of the Microbiome, Hepatology, vol.59, 6, 2014,pp 2413-2415
2015Caveolae control the anti-inflammatory phenotype of senescent endothelial cellsBertolino, Patrick; Coleman, Paul; Gamble, Jennifer; Lay, Angelina; Powter, Elizabeth; Tran, Minh; Vadas, Mathew; Parton, Robert G.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteCaveolae control the anti-inflammatory phenotype of senescent endothelial cells, Aging Cell, vol.14, 1, 2015,pp 102-111
2009Chronic increases in sphingosine kinase-1 activity induce a pro-inflammatory, pro-angiogenic phenotype in endothelial cellsGamble, Jennifer; Vadas, Mathew; Xia, Pu; Hahn, Christopher N.; Limaye, Vidya S.; Pitson, Stuart M.; Smith, Malcolm A.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteChronic increases in sphingosine kinase-1 activity induce a pro-inflammatory, pro-angiogenic phenotype in endothelial cells, Cellular and Molecular Biology Letters, vol.14, 3, 2009,pp 424-441
2015Deletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγChen, Jinbiao; Gamble, Jennifer; Kaczorowski, Dominik; McCaughan, Geoffrey William; Qi, Yanfei; Vadas, Mathew; Xia, Pu; Don, Anthony; Gao, Xin; Wang, Wei; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteDeletion of sphingosine kinase 1 ameliorates hepatic steatosis in diet-induced obese mice: Role of PPARγ, Biochimica et Biophysica Acta. Molecular and Cell Biology of Lipids, vol.1861, 2, 2015,pp 138-147
2009The effects of markedly raised intracellular sphingosine kinase-1 activity in endothelial cells.Gamble, Jennifer; Vadas, Mathew; Limaye, Vidya S.; Pitson, Stuart M.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe effects of markedly raised intracellular sphingosine kinase-1 activity in endothelial cells., Cellular & Molecular Biology Letters, vol.14, 3,pp 411-423
2009JAM-C Induces Endothelial Cell Permeability Through Its Association and Regulation of beta 3 IntegrinsGamble, Jennifer; Lu, Ying; Vadas, Mathew; Aurrand-Lions, Michel; Hahn, Chris; Imhof, Beat A.; Lee, Boris; Li, Xiaochun Chun; Stankovic, Milena; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteJAM-C Induces Endothelial Cell Permeability Through Its Association and Regulation of beta 3 Integrins, Arteriosclerosis, Thrombosis, and Vascular Biology, vol.29, 8, 2009,pp 1200-1206
2013Loss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic beta-cell death in diet-induced obese miceChen, Jinbiao; Lay, Angelina; Qi, Yanfei; Vadas, Mathew; Xia, Pu; Don, Anthony; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLoss of sphingosine kinase 1 predisposes to the onset of diabetes via promoting pancreatic beta-cell death in diet-induced obese mice, The FASEB Journal, vol.27, 10, 2013,pp 4294-4304
2015miR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancerBowen, David; Gamble, Jennifer; Shackel, Nicholas; Vadas, Mathew; Bertolino, Patrick; Brockhausen, Jennifer; d'Avigdor, William M; Grzelak, Candice; McCaughan, Geoffrey W.; Pok, Sharon; Tay, Szun Szun; Teoh, Narci C; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstitutemiR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer, Liver International, vol.35, 1, 2015,pp 240-253
2013Regulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27Gamble, Jennifer; Kench, James; Li, Jia; Lichtenstein, Ilana; Lu, Ying; McCaughan, Geoffrey William; Moses, Joshua; Shackel, Nicholas; Ting, Ka Ka; Tran, Nham; Vadas, Mathew; Young, Jennifer; Dunn, Louise; Goodall, Gregory; Gregory, Philip; Hahn, Christopher; Khachigian, Levon M.; Moller, Thorleif; Ng, Martin K.C; Prado-Lourenco, Leonel; Tsykin, Anna; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Chemistry; Schl Information Technologies; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteRegulation of vascular leak and recovery from ischaemic injury by general and VE-cadherin-restricted miRNA antagonists of miR-27, Blood, vol.122, 16, 2013,pp 2911-2919
2009Restoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathwayVadas, Mathew; Wang, Lijun; Xia, Pu; Sukocheva, Olga; Verrier, Emily; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteRestoring endocrine response in breast cancer cells by inhibition of the sphingosine kinase-1 signaling pathway, Endocrinology, vol.150, 10, 2009,pp 4484-4492
2017The RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cellsBertolino, Patrick; Chang, Garry Hoi-Kai; Coleman, Paul; Gamble, Jennifer; Hunter, Julie; Jormakka, Mika; Lay, Angelina; Lovelace, Michael; McCaughan, Geoffrey William; McGrath, Aaron; Powter, Elizabeth; Vadas, Mathew; Zhao, Yang; Kavallaris, Maria; Parker, A; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe RhoGAP protein ARHGAP18/SENEX localizes to microtubules and regulates their stability in endothelial cells, Molecular Biology of the Cell, vol.28, 8, 2017,pp 1066-1078
2008The role of sphingosine kinase 1 in cancer: Oncogene or non-oncogene addiction?Gamble, Jennifer; McCaughan, Geoffrey; Vadas, Mathew; Xia, Pu; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe role of sphingosine kinase 1 in cancer: Oncogene or non-oncogene addiction?, Biochimica et Biophysica Acta, vol.1781,(9),2008,pp 442-447
2009Sphingosine kinase regulates the rate of endothelial progenitor cell differentiationGamble, Jennifer; Vadas, Mathew; Bonder, Claudine S; Cassano, Carlos; Coates, P. Toby; Li, Xiaochun Chun; Lopez, Angel F.; Matthews, Tyson; Pitson, Stuart M.; Proia, Richard; Ramshaw, Hayley; Sun, Wai Y; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteSphingosine kinase regulates the rate of endothelial progenitor cell differentiation, Blood, vol.113, 9,pp 2108-2117
2009Sphingosine kinase-1 associates with integrin {alpha}V{beta}3 to mediate endothelial cell survivalGamble, Jennifer; Vadas, Mathew; Bonder, Claudine S; Hahn, Christopher N.; Li, Xiaochun Chun; Pitson, Stuart M.; Sun, Wai Y; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteSphingosine kinase-1 associates with integrin {alpha}V{beta}3 to mediate endothelial cell survival, The American Journal of Pathology: cellular and molecular biology of disease, vol.175, 5,pp 2217-2225
2010Stress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cellsBeck, Konstanze; Gamble, Jennifer; Grimshaw, Matthew; Stocker, Roland; Vadas, Mathew; Brautigan, Peter J.; Coleman, Paul; Hahn, Christopher N.; Li, Xiaochun; Lu, Ying; School of Medical Sciences: School of Medical Sciences; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Central Clinical School: Centenary InstituteStress-induced premature senescence mediated by a novel gene, SENEX, results in an anti-inflammatory phenotype in endothelial cells, Blood, vol.116, 19,pp 4016-4024