Browsing by Author Truscott, Roger

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Issue DateTitleAuthor(s)Citation
20063-Hydroxykynurenine oxidizes alpha-crystallin: potential role in cataractogenesis.Aquilina, J Andrew; Hains, Peter; Korlimbinis, Anastasia; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye Health3-Hydroxykynurenine oxidizes alpha-crystallin: potential role in cataractogenesis., Biochemistry 2005, vol.45,(6),2006,pp 1852-1860
2010Age-Dependant Deamidation of Life-Long Proteins in the Human LensHains, Peter; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthAge-Dependant Deamidation of Life-Long Proteins in the Human Lens, Investigative Ophthalmology & Visual Science, vol.51, 6,pp 3107-3114
2010Age-Dependent Denaturation of Enzymes in the Human Lens: A Paradigm for Organismic Aging?Korlimbinis, Anastasia; Truscott, Roger; Zhu, Xiangjia; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Save Sight & Eye Health Inst.Age-Dependent Denaturation of Enzymes in the Human Lens: A Paradigm for Organismic Aging?, Rejuvenation Research, vol.13, 5,pp 553-560
2005Age-related nuclear cataract-oxidation is the key.Truscott, Roger; Central Clinical School: Clinical Ophthal & Eye HealthAge-related nuclear cataract-oxidation is the key., Experimental Eye Research, vol.80,(5),2005,pp 709-725
2010alpha- and beta-Crystallins Modulate the Head Group Order of Human Lens Membranes during AgingTruscott, Roger; Gaus, Katharina; Lu, Yi; Magenau, Astrid; Mitchell, Todd W; Zhu, Xiangjia; Central Clinical School: Clinical Ophthal & Eye Healthalpha- and beta-Crystallins Modulate the Head Group Order of Human Lens Membranes during Aging, Investigative Ophthalmology & Visual Science, vol.51, 10,pp 5162-5167
2016Amyloid Plaque in the Human Brain Can Decompose from A?(1-40/1-42) by Spontaneous Nonenzymatic ProcessesLyons, Brian; Friedrich, Michael; Raftery, Mark; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.Amyloid Plaque in the Human Brain Can Decompose from A?(1-40/1-42) by Spontaneous Nonenzymatic Processes, Analytical Chemistry, vol.88, 5, 2016,pp 2675-2684
2012Degradation of an Old Human Protein: Age-Dependent Cleavage of γS-Crystallin Generates a Peptide that Binds to Cell MembranesTruscott, Roger; Friedrich, Michael; Lam, Jackson; Central Clinical School: Clinical Ophthal & Eye HealthDegradation of an Old Human Protein: Age-Dependent Cleavage of γS-Crystallin Generates a Peptide that Binds to Cell Membranes, Journal of Biological Chemistry, vol.287, 46, 2012,pp 39012-39020
2011Fatty Acid Uptake and Incorporation into Phospholipids in the Rat LensTruscott, Roger; Blanksby, Stephen J; Donaldson, Paul; Mitchell, Todd W; Nealon, Jessica R; Central Clinical School: Clinical Ophthal & Eye HealthFatty Acid Uptake and Incorporation into Phospholipids in the Rat Lens, Investigative Ophthalmology & Visual Science, vol.52, 2, 2011,pp 804-809
2008Free and bound water in normal and cataractous human lensesFriedrich, Michael; Heys, Karl; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthFree and bound water in normal and cataractous human lenses, Investigative Ophthalmology & Visual Science, vol.49,(5),2008,pp 1991-1997
2006Identification of 3-hydroxykynurenine bound to proteins in the human lens. A possible role in age-related nuclear cataract.Korlimbinis, Anastasia; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthIdentification of 3-hydroxykynurenine bound to proteins in the human lens. A possible role in age-related nuclear cataract., Biochemistry 2005, vol.45,(6),2006,pp 1950-1960
2009Identification of Abundant Alkyl Ether Glycerophospholipids in the Human Lens by Tandem Mass Spectrometry TechniquesTruscott, Roger; Blanksby, Stephen J; Deeley, Jane M; Mitchell, Todd W; Thomas, Michael C.; Central Clinical School: Clinical Ophthal & Eye HealthIdentification of Abundant Alkyl Ether Glycerophospholipids in the Human Lens by Tandem Mass Spectrometry Techniques, Analytical Chemistry, vol.81,(5),2009,pp 1920-1930
2006Identification of the new UV filter compound cysteine-l-3-hydroxykynurenine O-beta-d-glucoside in human lenses.Hains, Peter; Truscott, Roger; Jamie, Joanne F.; Mizdrak, Jasminka; Streete, Isla M.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthIdentification of the new UV filter compound cysteine-l-3-hydroxykynurenine O-beta-d-glucoside in human lenses., FEBS Letters, vol.580,(21),2006,pp 5071-5076
2010Imaging of Human Lens Lipids by Desorption Electrospray Ionization Mass SpectrometryTruscott, Roger; Zhu, Xiangjia; Blanksby, Stephen J; Cooks, R Graham; Deeley, Jane M; Ellis, Shane R; Mitchell, Todd W; Panhuis, Marc; Wu, Chunping; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Save Sight & Eye Health Inst.Imaging of Human Lens Lipids by Desorption Electrospray Ionization Mass Spectrometry, Journal of the American Society for Mass Spectrometry, vol.21, 12,pp 2095-2104
2012Instability of the cellular lipidome with ageTruscott, Roger; Blanksby, Stephen J; Deeley, Jane M; Ellis, Shane R; Hughes, Jessica; Leisch, Friedrich; Mitchell, Todd W; Central Clinical School: Clinical Ophthal & Eye HealthInstability of the cellular lipidome with age, Age, vol.34, 4, 2012,pp 935-947
2010Large scale binding of {alpha}-crystallin to cell membranes of aged normal human lenses; a phenomenon that can be induced by mild thermal stressFriedrich, Michael; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthLarge scale binding of {alpha}-crystallin to cell membranes of aged normal human lenses; a phenomenon that can be induced by mild thermal stress, Investigative Ophthalmology & Visual Science, vol.51, 10,pp 5145-5152
2004Massive Increase In The Stiffness Of The Human Lens Nucleus With Age: The Basis For Presbyopia?Truscott, Roger; Cram, Sandra Leigh; Heys, Karl Robert; Central Clinical School: Clinical Ophthal & Eye HealthMassive Increase In The Stiffness Of The Human Lens Nucleus With Age: The Basis For Presbyopia?, Molecular Vision, vol.10,(114),2004,pp 956-963
2009Membrane association of proteins in the aging human lens: profound changes take place in the 5th decade of lifeFriedrich, Michael; Truscott, Roger; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthMembrane association of proteins in the aging human lens: profound changes take place in the 5th decade of life, Investigative Ophthalmology & Visual Science, vol.50, 10,pp 4786-4793
2005Molecular evidence that melatonin is enzymatically oxidized in a different manner than tryptophan: investigations with both indoleamine 2,3-dioxygenase and myeloperoxidase.Truscott, Roger; Bertin, Sophie; Bouchet, Jean-Paul; Boutin, Jean A.; Chomarat, Pascale; Coge, Francis; Delagrange, Phillippe; Ferry, Gilles; Lambert, Pierre-Herve; Serkiz, Bernard; Ubeaud, Caroline; Central Clinical School: Clinical Ophthal & Eye HealthMolecular evidence that melatonin is enzymatically oxidized in a different manner than tryptophan: investigations with both indoleamine 2,3-dioxygenase and myeloperoxidase., Biochemical Journal, vol.388,(Part 1),2005,pp 205-215
2012Molecular signatures of long-lived proteins: autolytic cleavage adjacent to serine residuesFriedrich, Michael; Lyons, Brian; Truscott, Roger; Aquilina, John; McArthur, Jason D.; Song, Xiaomin; Su, Shih-Ping; Xavier, Dylan; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthMolecular signatures of long-lived proteins: autolytic cleavage adjacent to serine residues, Aging Cell, vol.11, 6, 2012,pp 1125-1127
2003Movement of cysteine in intact monkey lenses: the major site of entry is the germinative regionSweeney, Matthew; Truscott, Roger; Garland, Donita L; Medicine; Central Clinical School: Clinical Ophthal & Eye HealthMovement of cysteine in intact monkey lenses: the major site of entry is the germinative region, Experimental Eye Research, vol.77,(2),2003,pp 245-251