Browsing by Author Sluyter, Ronald

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Issue DateTitleAuthor(s)Citation
2005A 50 intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian populationDao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Skarratt, K; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineA 50 intronic splice site polymorphism leads to a null allele of the P2X7 gene in 1–2% of the Caucasian population, FEBS Letters (2005), vol.579,(12),2005,pp 2675-2678
2007Abstract: A single nucleotide polymorphism in the P2X7 gene lends susceptibility to extrapulmonary tuberculosisBritton, Warwick; Fernando, Suran; Marks, Guy; Saunders, Bernadette; Sluyter, Ronald; Wiley, Sharron; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Woolcock Inst. of Medical Research; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Central Clinical School: MedicineAbstract: A single nucleotide polymorphism in the P2X7 gene lends susceptibility to extrapulmonary tuberculosis, Tissue Antigens, vol.66,(5),2007,pp 532-533
2004An Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor.Barden, Julian; Dao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Shemon, Anne; Skarratt, K; Sluyter, Ronald; Wiley, James; Clarke, Alison L; Petrou, Steven; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineAn Arg307 To Gln Polymorphism Within The Atp-Binding Site Causes Loss Of Function Of The Human P2X7 Receptor., Journal of Biological Chemistry, vol.279,(30),2004,pp 31287-31295
2007Canine erythrocytes express the P2X7 receptor: greatly increased function compared to human erythrocytesEslick, Guy; Georgiou, Jennifer; Shemon, Anne; Sluyter, Ronald; Stevenson, Ryan; Taylor, Rosanne; Wiley, James; Hughes, William E; School of Public Health: Public Health; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Vet Science Faculty; Nepean Clinical School: MedicineCanine erythrocytes express the P2X7 receptor: greatly increased function compared to human erythrocytes, American Journal of Physiology: Regulatory, Integrative and Comparative Physiology, vol.293,(5),2007,pp R2090-R2098
2013CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulationStokes, Leanne; Pupovac, Aleta; Sluyter, Ronald; Nepean Clinical School: MedicineCAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation, Purinergic Signalling, vol.9, 4, 2013,pp 609-619
2004Chelerythrine And Other Benzophenanthridine Alkaloids Block The Human P2X(7) ReceptorConigrave, Arthur; Shemon, Anne; Sluyter, Ronald; Wiley, James; Molecular & Microbial Bioscien; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineChelerythrine And Other Benzophenanthridine Alkaloids Block The Human P2X(7) Receptor, British Journal of Pharmacology, vol.142,(6),2004,pp 1015-1019
2009Circulating interleukin-18 concentrations and a loss-of-function P2X7 polymorphism in heart failureEslick, Guy; Sluyter, Ronald; Thampan, Binu; McLean, Anthony S; Nalos, Marek; School of Public Health: Public Health; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineCirculating interleukin-18 concentrations and a loss-of-function P2X7 polymorphism in heart failure, International Journal of Cardiology, vol.N/A,(N/A),2009,pp N/A-N/A
2004Extracellular ATP Increases Cation Fluxes In Human Erythrocytes By Activation Of The P2X7 ReceptorBarden, Julian; Shemon, Anne; Sluyter, Ronald; Wiley, James; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineExtracellular ATP Increases Cation Fluxes In Human Erythrocytes By Activation Of The P2X7 Receptor, Journal of Biological Chemistry, vol.279,(43),2004,pp 44749-44755
2005Gene Dosage Determines the Negative Effects of Polymorphic Alleles of the P2X7 Receptor on Adenosine Triphosphate–Mediated Killing of Mycobacteria by Human MacrophagesBritton, Warwick; Fernando, Sujatha; Saunders, Bernadette; Skarratt, K; Sluyter, Ronald; Wiley, James; Central Clinical School: Centenary Institute; School of Rural Health: Medicine; Central Clinical School: Centenary Institute; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineGene Dosage Determines the Negative Effects of Polymorphic Alleles of the P2X7 Receptor on Adenosine Triphosphate–Mediated Killing of Mycobacteria by Human Macrophages, The Journal of Infectious Diseases 2005, vol.192,(1),2005,pp 149-155
2007The genetic control of susceptibility to Mycobacterium tuberculosisBritton, Warwick; Fernando, Sujatha; Saunders, Bernadette; Sluyter, Ronald; Wiley, James; Central Clinical School: Centenary Institute; School of Rural Health: Medicine; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineThe genetic control of susceptibility to Mycobacterium tuberculosis in Decoding the Genomic Control of Immune Reactions, John Wiley & Sons, 2007, pp. 79-89; discussion 89-92, 208-9
2004Glu496 To Ala Polymorphism In The P2X7 Receptor Impairs ATP-Induced IL-1 Beta Release From Human Monocytes.Shemon, Anne; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineGlu496 To Ala Polymorphism In The P2X7 Receptor Impairs ATP-Induced IL-1 Beta Release From Human Monocytes., Journal of Immunology, vol.172,(6),2004,pp 3399-3405
2008Host tissue damage signal ATP impairs IL-12 and IFN {gamma} secretion in LPS stimulated whole human bloodHuang, Stephen; McLean, Anthony; Nalos, Marek; Nanan, Brigitte; Nanan, Ralph; Sluyter, Ronald; Khan, Alamgir; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Paediatrics & Child Health; School of Medical Sciences: PathologyHost tissue damage signal ATP impairs IL-12 and IFN {gamma} secretion in LPS stimulated whole human blood, Intensive Care Medicine, vol.34, 10, 2008,pp 1891-1897
2005Human Epidermal and Monocyte-Derived Langerhans Cells Express Functional P2X7 ReceptorsChristopherson, Richard; Fuller, Stephen; Georgiou, Jennifer; Martin, Christopher; Skarratt, K; Sluyter, Ronald; Wiley, James; Molecular & Microbial Bioscien; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Surgery; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineHuman Epidermal and Monocyte-Derived Langerhans Cells Express Functional P2X7 Receptors, THE JOURNAL OF INVESTIGATIVE DERMATOLOGY 2005, vol.125,(3),2005,pp 482-490
2003An Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptorBarden, Julian; Dao-Ung, L; Fuller, Stephen; Gu, Baijun (Ben); Li, Changping; Shemon, Anne; Sluyter, Ronald; Wiley, James; Petrou, Steven; Smart, Megan L; School of Medical Sciences: Anatomy & Histology; Nepean Clinical School: Medicine; Northern Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineAn Ile-568 to Asn polymorphism prevents normal trafficking and function of the human P2X7 receptor, Journal of Biological Chemistry, vol.278,(19),2003,pp 17108-17113
2007Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonistShemon, Anne; Sluyter, Ronald; Stokes, Leanne; Wiley, James; Manley, Paul W; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Nepean Clinical School: MedicineInhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist, Biochemical and Biophysical Research Communications (2005), vol.365,(Available online 20 November 2007),2007,pp 515-520
2003A loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of MycobacteriaBritton, Warwick; Fernando, Sujatha; Saunders, Bernadette; Sluyter, Ronald; Wiley, James; Central Clinical School: Centenary Institute; School of Public Health: Rural Health; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineA loss-of-function polymorphism in the human P2X7 receptor abolishes ATP-mediated killing of Mycobacteria, Journal of Immunology, vol.171,(10),2003,pp 5442-5446
2010Murine epidermal Langerhans cells and keratinocytes express functional P2X7 receptorsByrne, Scott; Sluyter, Ronald; Taylor, Rosanne; Tran, Jimmy; Wiley, James; Pupovac, Aleta; Central Clinical School: Medicine; School of Medical Sciences: Pathology; Vet Science Faculty; Centre Regional Ed - Orange; Nepean Clinical School: MedicineMurine epidermal Langerhans cells and keratinocytes express functional P2X7 receptors, Experimental Dermatology, vol.19, 8,pp e151-e157
2005Novel protein kinase C Isoforms mediate both extracellular ATP and PMA-induced phospholipase D activity in B-lymphocytesShemon, Anne; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineNovel protein kinase C Isoforms mediate both extracellular ATP and PMA-induced phospholipase D activity in B-lymphocytes, Tissue Antigens, vol.66,(5),2005,pp 541-541
2007P2X(7) receptor activation causes phosphatidylserine exposure in human erythrocytesShemon, Anne; Sluyter, Ronald; Wiley, James; Nepean Clinical School: Medicine; School of Medical Sciences: Pathology; Nepean Clinical School: MedicineP2X(7) receptor activation causes phosphatidylserine exposure in human erythrocytes, Biochemical and Biophysical Research Communications (2005), vol.355,(1),2007,pp 169-173
2009The P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types.Sluyter, Ronald; Stevenson, Ryan; Taylor, Rosanne; Wiley, James; School of Medical Sciences: Pathology; Nepean Clinical School: Medicine; Vet Science Faculty; Nepean Clinical School: MedicineThe P2X(7) receptor mediates the uptake of organic cations in canine erythrocytes and mononuclear leukocytes: comparison to equivalent human cell types., Purinergic Signalling, vol.5, 3,pp 385-394