Browsing by Author Rizos, Helen

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Issue DateTitleAuthor(s)Citation
2012Absence of Distinguishing Senescence Traits in Human Melanocytic NeviBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Rizos, Helen; Scolyer, Richard; Scurr, Lyndee; Thompson, John; Tran, Sieu; Desilva, Chitra; Haferkamp, Sebastian; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgery; Western Clinical School: Medicine (Westmead)Absence of Distinguishing Senescence Traits in Human Melanocytic Nevi, The Journal of Investigative Dermatology, vol.132, 9, 2012,pp 2226-2234
2015Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanismsKefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Pupo, Gulietta; Rizos, Helen; Scolyer, Richard; Thompson, John; Becker, Jurgen C; Berking, Carola; Eroglu, Zeynep; et al, Various; Gogas, Helen; Gutzmer, R.; Johnson, Douglas B; Sucker, Antje; Ye, Fei; Zhao, Shilin; Zimmer, Lisa; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Pathology; Central Clinical School: SurgeryAcquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms, European Journal of Cancer, vol.51, 18, 2015,pp 2792-2799
2012Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK InhibitionBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteAcquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition, The Journal of Investigative Dermatology, vol.132, 7, 2012,pp 1850-1859
2010Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondriaBecker, Therese; Frausto, Monika; Fung, Carina; Irvine, Malama; Kefford, Richard (Rick); Mijatov, Branka; Philipsz, Suzanah; Rizos, Helen; Gallagher, S. J.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Infectious Diseases; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium InstituteAmino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria, Cell Cycle, vol.9, 4,pp 829-839
2008Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian CancerBalleine, Rosemary; Chiew, Yoke-Eng; deFazio, Anna; Guminski, Alexander; Harnett, Paul; Kennedy, Catherine Jane; Lei, Ying; Pryor, Kylie; Rizos, Helen; Scurr, Lyndee; Brand, Alison; Byth, Karen; Sharma, Raghwa; Wain, Gerard V.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Obstetrics & Gynaecology; Western Clinical School: Westmead Millennium Institute; Medicine Faculty Office; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Medicine; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Ankyrin Repeat Domain 1, ANKRD1, a Novel Determinant of Cisplatin Sensitivity Expressed in Ovarian Cancer, Clinical Cancer Research, vol.14, 21, 2008,pp 6924-6932
2013Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in MelanomaBecker, Therese; Carlino, Matteo; Gowrishankar, Kavitha; Kefford, Richard (Rick); Long, Georgina; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Snoyman, Stephanie; Saunders, Catherine; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteAntiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma, Molecular Cancer Therapeutics, vol.12, 7, 2013,pp 1332-1342
2010Apoptosis of Human Melanoma Cells Induced by Inhibition of B-RAFV600E Involves Preferential Splicing of BimSBecker, Therese; Rizos, Helen; Croft, A.; Hersey, Peter; Jiang, Chen Chen; Lai, F; Liu, H.; Tay, KH; Thorne, R F; Yang, F.; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteApoptosis of Human Melanoma Cells Induced by Inhibition of B-RAFV600E Involves Preferential Splicing of BimS, Cell Death & Disease, vol.1, 9,pp e69-1-e69-14
2006The ARF tumour suppressor.Gallagher, Stuart; Kefford, Richard (Rick); Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteThe ARF tumour suppressor., The International Journal of Biochemistry & Cell Biology, vol.38,(10),2006,pp 1637-1641
2003Association of p14ARF with the p120E4F transciptional represssor enhances cell cycle inhibitionBadhwar, Prerna; Becker, Therese; Diefenbach, Eve; Kefford, Richard (Rick); Rizos, Helen; Woodruff, Sarah; Rooney, Robert J.; Medicine; Western Clinical School: Westmead Millennium Institute; Business Liaison Office; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Association of p14ARF with the p120E4F transciptional represssor enhances cell cycle inhibition, Journal of Biological Chemistry, vol.278,(7),2003,pp 4981-4989
2002Association of p14ARF with the p120E4F Transcriptional Repressor Enhances Cell Cycle InhibitionBadhwar, Prerna; Becker, Therese; Kefford, Richard (Rick); Rizos, Helen; Diefenbach, Eve; Rooney, Robert J.; Woodruff, Sarah; Medicine; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteAssociation of p14ARF with the p120E4F Transcriptional Repressor Enhances Cell Cycle Inhibition, Journal of Biological Chemistry, vol.278,(7),2002,pp 4981-4989
2015The BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic functionBrodie, Kirsty Maree; deFazio, Anna; Henderson, Beric; Lei, Ying; Martino-Echarri, Estefania; Marzec, Kamila; Mills, Kate; Mok, Myth; Rizos, Helen; Tembe, Varsha; Boadle, Ross; Kettle, Emma; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Medicine; Western Clinical School: Westmead Institute for Medical Res; Research Grants and Contracts; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical ResThe BARD1 BRCT domain contributes to p53 binding, cytoplasmic and mitochondrial localization, and apoptotic function, Cellular Signalling, vol.27, 9, 2015,pp 1763-1771
2017Biomarker accessible and chemically addressable mechanistic subtypes of braf melanomaLong, Georgina; Rizos, Helen; Ding, Ming; Eskiocak, Banu; et al, Various; Garcia-Rodriguez, Jose; Humphries, Caroline G.; Kollipara, Rahul K.; McMillan, Elizabeth A.; Mendiratta, Saurabh; Wang, Changguang; Zhang, Hailei; Northern Clinical School: Medicine; Western Clinical School: Westmead Institute for Medical ResBiomarker accessible and chemically addressable mechanistic subtypes of braf melanoma, Cancer Discovery, vol.7, 8, 2017,pp 832-851
2014BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impactBecker, Therese; Boyd, Suzanah; Carlino, Matteo; Fung, Carina; Haydu, Lauren; Howle, Julie; Kefford, Richard (Rick); Long, Georgina; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Scolyer, Richard; Thompson, John; Hyman, Jessica; Menzies, Alexander; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Infectious Diseases; Central Clinical School: Surgery; Western Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: SurgeryBRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact, Clinical Cancer Research, vol.20, 7, 2014,pp 1965-1977
2009The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4aBecker, Therese; Diefenbach, Eve; Dijkstra, Menno; Frausto, Monika; Haferkamp, Sebastian; Kefford, Richard (Rick); Mann, Graham; Rizos, Helen; Scolyer, Richard; Scurr, Lyndee; Reisman, David N.; Western Clinical School: Westmead Millennium Institute; Sydnovate; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School (Westmead): Office; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead)The chromatin remodelling factor BRG1 is a novel binding partner of the tumor suppressor p16INK4a, Molecular Cancer, vol.8,(4),2009,pp 4-1-4-12
2015Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanomaCarlino, Matteo; Lee, Jenny H J; Long, Georgina; Scolyer, Richard; Tembe, Varsha; Boyd, Suzanah C; Cooper, Adam; et al, Various; Freeman, James; Gray, Elin S; Khattak, Muhammad A; Lo, Johnny; Lomma, Chris; Pereira, Michelle R; Reid, Anna L; Rizos, Helen; Siew, Kelvin; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Pathology; Western Clinical School: Westmead Institute for Medical ResCirculating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma, Oncotarget, vol.N/A, N/A, 2015,pp N/A-N/A
2017Clinical significance of intronic variants in BRAF inhibitor resistant melanomas with altered BRAF transcript splicingCarlino, Matteo; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Pedersen, Bernadette; Pupo, Gulietta; Rizos, Helen; Scolyer, Richard; Boyd, Suzanah C; Fung, Carina; Hayward, Nicholas K; Johansson, Peter; Westmead Clinical School: Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Westmead Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: PathologyClinical significance of intronic variants in BRAF inhibitor resistant melanomas with altered BRAF transcript splicing, Biomarker Research, vol.5, 17, 2017,pp 1-4
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2014Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanomaCarlino, Matteo; Fung, C.; Gowrishankar, Kavitha; Hersey, Peter; Kefford, Richard (Rick); Long, Georgina; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Todd, Jason; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteDifferential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma, Molecular Oncology, vol.8, 3, 2014,pp 544-554
2013Effects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment and on progressionHaydu, Lauren; Howle, Julie; Kefford, Richard (Rick); Long, Georgina; Rizos, Helen; Scolyer, Richard; Sharma, Raghwa; Tembe, Varsha; Thompson, John; Wilmott, James; Central Clinical School: Surgery; Western Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgery; Central Clinical School: SurgeryEffects of BRAF inhibitors on human melanoma tissue before treatment, early during treatment and on progression, Pigment Cell and Melanoma Research, vol.26, 4, 2013,pp 499-508
2005Enforced expression of p14ARF induces p53-dependent cell cycle arrest but not apoptosis.Gallagher, Stuart; Kefford, Richard (Rick); Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteEnforced expression of p14ARF induces p53-dependent cell cycle arrest but not apoptosis., Cell Cycle 2005, vol.4,(3),2005,pp 465-472