Browsing by Author Peacock, Lauren

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Issue DateTitleAuthor(s)Citation
2014Activated Protein C (APC) can Increase Bone Anabolism via a Protease Activated Receptor (PAR)1/2 Dependent MechanismChan, Benjamin; Cheng, Tegan Laura; Jackson, Christopher; Little, David; Murphy, Ciara; Schindeler, Aaron; Xue, Meilang; Cheng, Tegan; Kolind, Mille; Mikulec, Kathy; Park, Sang-Youel; Peacock, Lauren; Shen, Kaitlin; Northern Clinical School: Surgery; Childrens Hospital Westmead: Paediatrics & Child Health; Northern Clinical School: Medicine; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Northern Clinical School: MedicineActivated Protein C (APC) can Increase Bone Anabolism via a Protease Activated Receptor (PAR)1/2 Dependent Mechanism, Journal of Orthopaedic Research, vol.32, 12, 2014,pp 1549-1556
2011Characterization of the Bone Phenotype and Fracture Repair in Osteopetrotic Incisors Absent RatsLittle, David; Schindeler, Aaron; McDonald, Michelle M; Mikulec, Kathy; Morse, Alyson; Peacock, Lauren; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child HealthCharacterization of the Bone Phenotype and Fracture Repair in Osteopetrotic Incisors Absent Rats, Journal of Orthopaedic Research: a journal for musculoskeletal investigation, vol.29, 5, 2011,pp 726-733
2014A collagen-hydroxyapatite scaffold allows for binding and co-delivery of recombinant bone morphogenetic proteins and bisphosphonatesCantrill, Laurence; Little, David; Murphy, Ciara; Schindeler, Aaron; Yu, Nicole; Gleeson, John; Mikulec, Kathy; O'Brien, Fergal; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthA collagen-hydroxyapatite scaffold allows for binding and co-delivery of recombinant bone morphogenetic proteins and bisphosphonates, Acta Biomaterialia, vol.10, N/A, 2014,pp 2250-2258
2017Combination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfectaCheng, Tegan Laura; Little, David; Munns, Craig; Schindeler, Aaron; Kneissel, M; Kramer, I; Mikulec, Kathy; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthCombination sclerostin antibody and zoledronic acid treatment outperforms either treatment alone in a mouse model of osteogenesis imperfecta, Bone, vol.101, N/A, 2017,pp 96-103
2015Endochondral fracture healing with external fixation in the Sost knockout mouse results in earlier fibrocartilage callus removal and increased bone volume fraction and strengthLittle, David; Morse, Alyson; Yu, Nicole; Kneissel, M; Kramer, I; McDonald, Michelle M; Mikulec, Kathy; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthEndochondral fracture healing with external fixation in the Sost knockout mouse results in earlier fibrocartilage callus removal and increased bone volume fraction and strength, Bone, vol.71, N/A, 2015,pp 155-163
2017Fabrication of a Biodegradable Implant with Tunable Characteristics for Bone Implant ApplicationsDehghani, Fariba; Fathi, Ali; Little, David; Maitz, Peter; Manavi Tehrani, Iman; Mirmohseni, Farid; Schindeler, Aaron; Wang, Yiwei; Cheng, Tegan L.; Peacock, Lauren; Chemical & Biomolecular Engineering; Chemical & Biomolecular Engineering; Childrens Hospital Westmead: Paediatrics & Child Health; Concord Clinical School: Surgery; Chemical & Biomolecular Engineering; Chemical and Biomolecular Engineering Foundation; Childrens Hospital Westmead: Paediatrics & Child Health; Concord Clinical School: ANZAC Research InstituteFabrication of a Biodegradable Implant with Tunable Characteristics for Bone Implant Applications, Biomacromolecules, vol.18, 6, 2017,pp 1736-1746
2010In vivo local co-delivery of recombinant human bone morphogenetic protein-7 and pamidronate via poly-D, L-lactic acidLittle, David; Ruys, Andrew; Schindeler, Aaron; Yu, Nicole; Baldock, Paul A.; Mikulec, Kathy; Peacock, Lauren; Children's Hospital Westmead: Paediatrics & Child Health; Aerospace Mech & M'tronic Eng; Children's Hospital Westmead: Paediatrics & Child Health; Aerospace Mech & M'tronic EngIn vivo local co-delivery of recombinant human bone morphogenetic protein-7 and pamidronate via poly-D, L-lactic acid, European Cells and Materials, vol.20, N/A,pp 431-442
2012Inhibition of Sclerostin by Systemic Treatment with Sclerostin Antibody Enhances Healing of Proximal Tibial Defects in Ovariectomized RatsLittle, David; Baldock, Paul A.; Birke, Oliver; Ke, Hua Zhu; Liu, Min; McDonald, Michelle M; Mikulec, Kathy; Morse, Alyson; Peacock, Lauren; Yu, N.Y.C.; Children's Hospital Westmead: Paediatrics & Child HealthInhibition of Sclerostin by Systemic Treatment with Sclerostin Antibody Enhances Healing of Proximal Tibial Defects in Ovariectomized Rats, Journal of Orthopaedic Research: a journal for musculoskeletal investigation, vol.30, 10, 2012,pp 1541-1548
2010Intermittent PTH (1-34) Does Not Increase Union Rates in Open Rat Femoral Fractures and Exhibits Attenuated Anabolic Effects Compared to Closed FracturesLittle, David; Amanat, Negin; Godfrey, Craig; McDonald, Michelle M; Mikulec, Kathy; Morse, Alyson; Peacock, Lauren; Tagil, Magnus; Children's Hospital Westmead: Paediatrics & Child HealthIntermittent PTH (1-34) Does Not Increase Union Rates in Open Rat Femoral Fractures and Exhibits Attenuated Anabolic Effects Compared to Closed Fractures, Bone, vol.46, 3,pp 852-859
2017Limitations of the Pax7-creER(T2) transgene for driving deletion of Nf1 in adult mouse muscleLittle, David; Schindeler, Aaron; Summers, Matthew; Mikulec, Kathy; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Exercise & Sport ScienceLimitations of the Pax7-creER(T2) transgene for driving deletion of Nf1 in adult mouse muscle, International Journal of Developmental Biology, vol.61, 8-Sep, 2017,pp 531-536
2017Local co-delivery of rhBMP-2 and cathepsin K inhibitor L006235 in poly(D,L-lactide-co-glycolide) nanospheresCantrill, Laurence; Dehghani, Fariba; Fathi, Ali; Little, David; Murphy, Ciara; Schindeler, Aaron; Yu, Nicole; Mikulec, Kathy; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Chemical & Biomolecular Engineering; Chemical & Biomolecular Engineering; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthLocal co-delivery of rhBMP-2 and cathepsin K inhibitor L006235 in poly(D,L-lactide-co-glycolide) nanospheres, Journal of Biomedical Materials Research. Part B: Applied Biomaterials, vol.105B, 1, 2017,pp 136-144
2015Local delivery of the cationic steroid antibiotic CSA-90 enables osseous union in a rat open fracture model of Staphylococcus aureus infectionCheng, Tegan Laura; Little, David; Matthews, Ross; Mikulec, Kathy; Peacock, Lauren; Schindeler, Aaron; Sullivan, Kate; Yu, Nicole; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthLocal delivery of the cationic steroid antibiotic CSA-90 enables osseous union in a rat open fracture model of Staphylococcus aureus infection, Journal of Bone and Joint Surgery: American Volume, vol.97, 4, 2015,pp 302-309
2013Matrix Metalloproteinase – Driven Endochondral Fracture Union Proceeds Independently of Osteoclast ActivityLittle, David; Baldock, Paul A.; Kostenuik, P.; McDonald, Michelle M; Mikulec, Kathy; Morse, Alyson; Peacock, Lauren; Children's Hospital Westmead: Paediatrics & Child HealthMatrix Metalloproteinase – Driven Endochondral Fracture Union Proceeds Independently of Osteoclast Activity, Journal of Bone and Mineral Research, vol.28, 7, 2013,pp 1550-1560
2013Modulation of anabolic and catabolic responses via a porous polymer scaffold manufactured using thermally induced phase separationLittle, David; Ruys, Andrew; Schindeler, Aaron; Yu, Nicole; Cooper-White, Justin; Fitzpatrick, Jane; Mikulec, Kathy; Peacock, Lauren; Children's Hospital Westmead: Paediatrics & Child Health; Aerospace Mech & M'tronic Eng; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child HealthModulation of anabolic and catabolic responses via a porous polymer scaffold manufactured using thermally induced phase separation, European Cells and Materials, vol.25, N/A, 2013,pp 190-203
2012A murine model of neurofibromatosis type 1 tibial pseudarthrosis featuring proliferative fibrous tissue and osteoclast-like cellsAlexander, Ian; Bobyn, Justin; El-Hoss, Jad; Little, David; Schindeler, Aaron; Sullivan, Kate; Baldock, Paul A.; Cheng, Tegan; Mikulec, Kathy; Peacock, Lauren; Yu, Nicole; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child HealthA murine model of neurofibromatosis type 1 tibial pseudarthrosis featuring proliferative fibrous tissue and osteoclast-like cells, Journal of Bone and Mineral Research, vol.27, 1, 2012,pp 68-78
2011Myogenic progenitors contribute to open but not closed fracture repairLittle, David; Liu, Renjing; Schindeler, Aaron; Birke, Oliver; Mikulec, Kathy; Morse, Alyson; Peacock, Lauren; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child HealthMyogenic progenitors contribute to open but not closed fracture repair, BMC Musculoskeletal Disorders, vol.12, N/A, 2011,pp 288 - 1-288 - 9
2013Neuropeptide Y modulates fracture healing through Y1 receptor signalingLittle, David; Baldock, Paul A.; Herzog, Herbert; Lamghari, Meriem; McDonald, Michelle M; Mikulec, Kathy; Peacock, Lauren; Sousa, Daniela M.; Children's Hospital Westmead: Paediatrics & Child HealthNeuropeptide Y modulates fracture healing through Y1 receptor signaling, Journal of Orthopaedic Research, vol.31, 10, 2013,pp 1570-1578
2015PTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in RatsCantrill, Laurence; Little, David; Murphy, Ciara; Schindeler, Aaron; Mikulec, Kathy; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthPTH(1-34) Treatment Increases Bisphosphonate Turnover in Fracture Repair in Rats, Journal of Bone and Mineral Research, vol.30, 6, 2015,pp 1022-1029
2016RAP-011 augments callus formation in closed fractures in ratsCheng, Tegan Laura; Little, David; Morse, Alyson; Schindeler, Aaron; Mikulec, Kathy; Peacock, Lauren; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthRAP-011 augments callus formation in closed fractures in rats, Journal of Orthopaedic Research, vol.34, 2, 2016,pp 320-330
2010Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedicsLittle, David; Liu, Renjing; Ruys, Andrew; Schindeler, Aaron; Yu, Nicole; Baldock, Paul A.; Kijumnuayporn, Sandy; McDonald, Michelle M.; Mikulec, Kathy; Morse, Alyson; Peacock, Lauren; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Aerospace Mech & M'tronic Eng; Children's Hospital Westmead: Paediatrics & Child Health; Aerospace Mech & M'tronic EngRapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics, BMC Musculoskeletal Disorders, vol.11, N/A,pp 105-1-105-9