Browsing by Author O'Brien-Brown, James

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Issue DateTitleAuthor(s)Citation
2017Discovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonistsBarron, Melissa; Jackson, Alexander; Kassiou, Michael; McDonnell, Michelle; Munoz, Lenka; O'Brien-Brown, James; Reekie, Tristan Andrew; Schiavini, Paolo; Werry, Eryn; Wilkinson, Shane; Noll, Benjamin D.; Wang, Shudong; School of Medical Sciences: Physiology; Research Grants and Contracts; Chemistry; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pathology; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; Medical Imaging and Radiation Sciences; ChemistryDiscovery and pharmacological evaluation of a novel series of adamantyl cyanoguanidines as P2X7 receptor antagonists, European Journal of Medicinal Chemistry, vol.130, N/A, 2017,pp 433-439
2017Pharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonistBarron, Melissa; Fuller, Stephen; Hibbs, David; Kassiou, Michael; O'Brien-Brown, James; Ong, Jennifer; Skarratt, Kristen; Werry, Eryn; Wilkinson, Shane; Chishty, Mansoor; Janssen, Bieneke; Stokes, Leanne; Vugts, Danielle J.; Windhorst, Albert D.; School of Medical Sciences: Physiology; Nepean Clinical School: Medicine; Pharmacy; Chemistry; Chemistry; Pharmacy; Nepean Clinical School: Medicine; Medical Imaging and Radiation Sciences; ChemistryPharmacological evaluation of novel bioisosteres of an adamantanyl benzamide P2X7 receptor antagonist, ACS Chemical Neuroscience, vol.8, 11, 2017,pp 2374-2380
2015Recent advances in the development of sigma-1 receptor ligandsBanister, Samuel; Beinat, Corinne; Kassiou, Michael; Manohar, Madhura; O'Brien-Brown, James; Medical Radiation Sciences; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; ChemistryRecent advances in the development of sigma-1 receptor ligands, Australian Journal of Chemistry: an international journal for chemical science, vol.N/A, N/A, 2015,pp N/A-N/A
2015Structure-activity relationship studies of SEN12333 analogues: Determination of the optimal requirements for binding affinities at alpha7 nAChRs through incorporation of known structural motifsBeinat, Corinne; Kassiou, Michael; O'Brien-Brown, James; Reekie, Tristan Andrew; Banister, Samuel D.; Coles, Carolyn; Grishin, Anton; Harvey, Andrew; Kolesik, Peter; OConnor, Susan; Olson, Thao T.; Tsanaktsidis, John; Xiao, Yingxian; Xie, Teresa; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; Medical Imaging and Radiation SciencesStructure-activity relationship studies of SEN12333 analogues: Determination of the optimal requirements for binding affinities at alpha7 nAChRs through incorporation of known structural motifs, European Journal of Medicinal Chemistry, vol.95, N/A, 2015,pp 277-301