Browsing by Author Mewett, Kenneth

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Issue DateTitleAuthor(s)Citation
2007(3-Aminocyclopentyl)methylphosphinic acids: Novel GABA(C) receptor antagonistsCollins (Chebib), Mary; Hanrahan, Jane; Johnston, Graham; Kumar, Rohan; Mewett, Kenneth; Morriss, Gwendolyn; Wooller, Soraya; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy(3-Aminocyclopentyl)methylphosphinic acids: Novel GABA(C) receptor antagonists, Neuropharmacology (2005), vol.52,(3),2007,pp 779-787
20063-Hydroxypyridazine 1-oxides as carboxylate bioisosteres: A new series of subtype-selective AMPA receptor agonists.Allan, Robin; Greenwood, Jeremy; Mewett, Kenneth; Martín, Belen Ortiz; Pickering, Darryl S.; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology3-Hydroxypyridazine 1-oxides as carboxylate bioisosteres: A new series of subtype-selective AMPA receptor agonists., Neuropharmacology (2005), vol.51,(1),2006,pp 52-59
2007Application of a Cyclodiene-Specific ELISA to Residue Monitoring of Agricultural Produce and the Environment in VietnamAllan, Robin; Kennedy, Ivan; Khurana, Jeevan; Lee, Nanju; Mewett, Kenneth; Tran, Hue; Wang, Shuo; Bui, Cach Tuyen; Bui, Van Thin; Chu, Pham Ngoc Son; Le, Van To; Nguyen, Thi Thu Trang; Nguyen, Thu Trang; Pham, Hung Viet; Pham, Ngoc Ha; Pham, Thi Anh; Vo, Thanh Hau; School of Medical Sciences: Pharmacology; Sustainable Ecosystems; Agriculture Faculty Admin; Agricult Chem & Soil Science; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School Land Water & Crop ScienApplication of a Cyclodiene-Specific ELISA to Residue Monitoring of Agricultural Produce and the Environment in Vietnam in Rational Environmental Management of Agrochemicals: Risk Assessment, Monitoring, and Remedial Action, American Chemical Society, 2007, pp. 245-258
2003Convulsant actions of CalycanthineCollins (Chebib), Mary; Connor, Mark; Duke, Colin; Duke, Rujee; Johnston, Graham; Mewett, Kenneth; Pharmacy; Northern Clinical School: Medicine; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyConvulsant actions of Calycanthine, Toxicology and Applied Pharmacology, vol.190,(1),2003,pp 58-64
2006Diastereoselective synthesis of (+/-)-(3-aminocyclopentane)alkylphosphinic acids, conformationally restricted analogues of GABA.Burden, Peter; Collins (Chebib), Mary; Crean, Colm; Eliopoulos, Con; Hanrahan, Jane; Johnston, Graham; Kumar, Rohan; Matos, Susana; Mewett, Kenneth; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyDiastereoselective synthesis of (+/-)-(3-aminocyclopentane)alkylphosphinic acids, conformationally restricted analogues of GABA., Organic & Biomolecular Chemistry, vol.4,(13),2006,pp 2642-2649
2008Flavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in miceCollins (Chebib), Mary; Fernandez, Sebastian; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyFlavan-3-ol derivatives are positive modulators of GABA(A) receptors with higher efficacy for the alpha(2) subtype and anxiolytic action in mice, Neuropharmacology, vol.55,(5),2008,pp 900-907
2012Flavan-3-ol esters: new agents for exploring modulatory sites on GABAA receptorsCollins (Chebib), Mary; Fernandez, Sebastian; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: PharmacologyFlavan-3-ol esters: new agents for exploring modulatory sites on GABAA receptors, British Journal of Pharmacology, vol.165, 4, 2012,pp 965-977
2003GABAc receptors as drug targetsCollins (Chebib), Mary; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyGABAc receptors as drug targets, CNS and Neurological Disorders, vol.2,(4),2003,pp 260-268
2009Guanidino Acids Act as p1 GABAc Receptor AntagonistsAllan, Robin; Collins, Mary; Duke, Rujee; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Park, Anna; Premoli, Isabella; Wong, Kit; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Western Clinical School: SurgeryGuanidino Acids Act as p1 GABAc Receptor Antagonists, Neurochemical Research, vol.34, 10, 2009,pp 1704-1711
2001An improved, versatile synthesis of the GABAc antagonists (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) and (piperidin-4-yl)methylphosphinic acid (P4MPA)Burden, Peter; Collins (Chebib), Mary; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyAn improved, versatile synthesis of the GABAc antagonists (1,2,5,6-tetrahydropyridin-4-yl)methylphosphinic acid (TPMPA) and (piperidin-4-yl)methylphosphinic acid (P4MPA), Royal Chemical Society. Journal. Perkin Transactions 1, vol.1,(N/A),2001,pp 2389-2392
2004Ionotropic Gaba Receptors As Therapeutic Targets For Memory And Sleep DisordersCollins (Chebib), Mary; Duke, Rujee; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyIonotropic Gaba Receptors As Therapeutic Targets For Memory And Sleep Disorders, Annual Reports in Medicinal Chemistry, vol.39,(1),2004,pp 13-23
2011Medicinal Chemistry of p GABAc ReceptorsCollins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Kim, Hye-Lim; Kumar, Rohan; Mewett, Kenneth; Ng, Clarissa; Yamamoto, Izumi; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; PharmacyMedicinal Chemistry of p GABAc Receptors, Future Medicinal Chemistry, vol.3, 2, 2011,pp 197-209
2006Modulation of Ionotropic GABA Receptors by Natural Products of Plant OriginCollins (Chebib), Mary; Duke, Rujee; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyModulation of Ionotropic GABA Receptors by Natural Products of Plant Origin in GABA, Academic Press Inc Elsevier Sc, San Diego, CA 92101-4495 USA, 2006, pp. 285-316
2006Modulation of ionotropic GABA receptors by natural products of plant origin.Collins (Chebib), Mary; Duke, Rujee; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyModulation of ionotropic GABA receptors by natural products of plant origin., Advances in Pharmacology, vol.54,(N/A),2006,pp 285-316
2004Mutations Of The 2' Proline In The M2 Domain Of The Human Gabac Rho1 Subunit Alter Agonist Responses.Carland, Jane; Collins (Chebib), Mary; Duke, Rujee; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Moore, Allison; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; PharmacyMutations Of The 2' Proline In The M2 Domain Of The Human Gabac Rho1 Subunit Alter Agonist Responses., Neuropharmacology (2005), vol.46,(N/A),2004,pp 770-781
2010Neurochemicals for the Investigation of GABAc ReceptorsCollins (Chebib), Mary; Hanrahan, Jane; Johnston, Graham; Mewett, Kenneth; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyNeurochemicals for the Investigation of GABAc Receptors, Neurochemical Research, vol.35, 12,pp 1970-1977
2004Synthesis And Resolution Of 2-Methyl Analogues Of GABACollins (Chebib), Mary; Duke, Rujee; Hibbs, David; Johnston, Graham; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologySynthesis And Resolution Of 2-Methyl Analogues Of GABA, Tetrahedron-Asymmetry, vol.15,(11),2004,pp 1745-1751
2002Trans-4-amino-2-methylbut-2-enoic acid (2-MeTACA) and (+/-)-trans-2-aminomethylcyclopropanecarboxylic acid ((+/-)-TAMP) can differentiate rat rho3 from human rho1 and rho2 recombinant GABA (C) receptors.Collins (Chebib), Mary; Duke, Rujee; Johnston, Graham; Mewett, Kenneth; Vien, Jimmy; Shingai, Ryuzo; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; Northern Clinical School: NCS OfficeTrans-4-amino-2-methylbut-2-enoic acid (2-MeTACA) and (+/-)-trans-2-aminomethylcyclopropanecarboxylic acid ((+/-)-TAMP) can differentiate rat rho3 from human rho1 and rho2 recombinant GABA (C) receptors., British Journal of Pharmacology, vol.135, 4,pp 883-889