Browsing by Author McAvoy, Johnston

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Issue DateTitleAuthor(s)Citation
2004Aberrant Lens Fiber Differentiation In Anterior Subcapsular Cataract Formation: A Process Dependent On Reduced Levels Of Pax6.Lovicu, Frank; McAvoy, Johnston; Steven, Philip; Saika, Shizuya; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Concord Clinical School: Age & Alzh Dis Rrch EducAberrant Lens Fiber Differentiation In Anterior Subcapsular Cataract Formation: A Process Dependent On Reduced Levels Of Pax6., Investigative Ophthalmology & Visual Science, vol.45,(6),2004,pp 1946-1953
2002Apoptosis is a feature of TGFb-induced cataractChamberlain, Coral; Lovicu, Frank; Maruno, K; McAvoy, Johnston; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye HealthApoptosis is a feature of TGFb-induced cataract, Clinical & Experimental Optometry, vol.85, 2,pp 76-82
2006Aqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling.Iyengar, Nagalaxmi; Lovicu, Frank; Lynch, Oonagh; McAvoy, Johnston; Patkunanathan, Bramilla; Rasko, John; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Deans Unit: (CIPHER); Central Clinical School: Centenary InstituteAqueous humour- and growth factor-induced lens cell proliferation is dependent on MAPK/ERK1/2 and Akt/PI3-K signalling., Experimental Eye Research, vol.83,(3),2006,pp 667-678
2015Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber DifferentiationMcAvoy, Johnston; Shelley, Elizabeth; Sugiyama, Yuki; Badouel, Caroline; McNeill, Helen; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Save Sight & Eye Health Inst.Atypical Cadherin Fat1 Is Required for Lens Epithelial Cell Polarity and Proliferation but Not for Fiber Differentiation, Investigative Ophthalmology & Visual Science, vol.56, 6, 2015,pp 4099-4107
2004Bmp And Activin Receptor Expression In Lens DevelopmentChen, Yongjuan; McAvoy, Johnston; de Iongh, Robert; Kokkinos, M; Clinical Schools; Central Clinical School: Clinical Ophthal & Eye HealthBmp And Activin Receptor Expression In Lens Development, Molecular Vision, vol.10,(69),2004,pp 566-576
2007Characterization of a familial t(16;22) balanced translocation associated with congenital cataract leads to identification of a novel gene, TMEM114, expressed in the lens and disrupted by the translocationGrigg, John; Jamieson, Robyn; Lovicu, Frank; McAvoy, Johnston; Black, Graeme C. M.; Carette, Martin; Donnai, D; Farrar, Nicola; Lloyd, I. C.; Mihelec, Marija; Perveen, Rahat; Scambler, Peter; Stewart, Katrina; Tam, Patrick P.L.; Central Clinical School: Clinical Ophthal & Eye Health; Children's Hospital Westmead: Paediatrics & Child Health; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye HealthCharacterization of a familial t(16;22) balanced translocation associated with congenital cataract leads to identification of a novel gene, TMEM114, expressed in the lens and disrupted by the translocation, Human Mutation, vol.28,(10),2007,pp 968-977
2007Crim1(KST264/KST264) mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systemsLovicu, Frank; McAvoy, Johnston; Gillinder, Kevin; Kolle, Gabriel; Little, Melisssa H.; Pennisi, David J.; Piper, Matthew David; Sohaskey, Michael L.; Wilkinson, Lorine; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye HealthCrim1(KST264/KST264) mice display a disruption of the Crim1 gene resulting in perinatal lethality with defects in multiple organ systems, DEVELOPMENTAL DYNAMICS, vol.236,(2),2007,pp 502-511
2004Deregulation Of Lens Epithelial Cell Proliferation And Differentiation During The Development Of Tgf?-Induced Anterior Subcapsular CataractAng, Sharyn; Chorazyczewska, Margaret; Lovicu, Frank; McAvoy, Johnston; Central Clinical School: Save Sight & Eye Health Inst.; SOPHI Admin; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye HealthDeregulation Of Lens Epithelial Cell Proliferation And Differentiation During The Development Of Tgf?-Induced Anterior Subcapsular Cataract, Developmental Neuroscience, vol.26,(5-6),2004,pp 446-455
2013Dexamethasone influences fgf-induced responses in lens epithelial explants and promotes the posterior capsule coverage that is a feature of glucocorticoid-induced cataractDawes, Lucy; Lovicu, Frank; McAvoy, Johnston; Wang, Chunxiao; Wen, Li; Liu, Yizhi; Central Clinical School: Save Sight & Eye Health Inst.; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Save Sight & Eye Health Inst.; Central Clinical School: Clinical Ophthal & Eye HealthDexamethasone influences fgf-induced responses in lens epithelial explants and promotes the posterior capsule coverage that is a feature of glucocorticoid-induced cataract, Experimental Eye Research, vol.111, N/A, 2013,pp 79-87
2007Duration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fateIyengar, L; Lovicu, Frank; McAvoy, Johnston; Rasko, John; Wang, Qin; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Centenary Institute; Medicine Faculty OfficeDuration of ERK1/2 phosphorylation induced by FGF or ocular media determines lens cell fate, Differentiation: ontogeny, neoplasia and differentiation therapy, vol.75,(7),2007,pp 662-668
2004Expression Of Frizzleds And Secreted Frizzled-Related Proteins (Sfrps) During Mammalian Lens DevelopmentChen, Yongjuan; Lovicu, Frank; McAvoy, Johnston; Stump, Richard; Clinical Schools; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Save Sight & Eye Health Inst.Expression Of Frizzleds And Secreted Frizzled-Related Proteins (Sfrps) During Mammalian Lens Development, International Journal of Developmental Biology, vol.48,(8-9),2004,pp 867-877
2011The fate of dividing cells during lens morphogenesis, differentiation and growthBoros, Jessica; Kallifatidis, Georgios; Lovicu, Frank; McAvoy, Johnston; Shin, Eun Hye H.; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; School of Medical Sciences: Anatomy & HistologyThe fate of dividing cells during lens morphogenesis, differentiation and growth, Experimental Eye Research, vol.92, 6, 2011,pp 502-511
2004Fibroblast Growth Factor 2: Roles Of Regulation Of Lens Cell Proliferation and Epithelial-Mesenchymal Transition In Response To InjuryMcAvoy, Johnston; Azhar, Muhamad; Doetschman, Thomas; Liu, Chia-Yang; Ohinishi, Yoshitaka; Ooshima, Akira; Saika, Shizuya; Tanaka, Takeshi; Whei-Yang Kao, Winston; Central Clinical School: Clinical Ophthal & Eye HealthFibroblast Growth Factor 2: Roles Of Regulation Of Lens Cell Proliferation and Epithelial-Mesenchymal Transition In Response To Injury, Molecular Vision, vol.10,(59),2004,pp 462-467
2016Fibrosis in the lens. Sprouty regulation of TGFbeta-signaling prevents lens EMT leading to cataractLovicu, Frank; McAvoy, Johnston; Shin, Eun Hye H.; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; School of Medical Sciences: Anatomy & HistologyFibrosis in the lens. Sprouty regulation of TGFbeta-signaling prevents lens EMT leading to cataract, Experimental Eye Research, vol.142, N/A, 2016,pp 92-101
2008Generation of transparency and cellular organization in lens explantsLovicu, Frank; McAvoy, Johnston; O'Connor, Michael; Wederell, Elizabeth; de Iongh, Robert; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; School of Medical Sciences: Anatomy & Histology; School of Medical Sciences: Anatomy & HistologyGeneration of transparency and cellular organization in lens explants, Experimental Eye Research, vol.86,(5),2008,pp 734-745
2005Growth factor regulation of lens development.Lovicu, Frank; McAvoy, Johnston; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye HealthGrowth factor regulation of lens development., Developmental Biology, vol.280,(1),2005,pp 1-14
2010Growth Factor Signaling in Vitreous Humor-Induced Lens Fiber DifferentiationLovicu, Frank; McAvoy, Johnston; Wang, Qian; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Clinical NursingGrowth Factor Signaling in Vitreous Humor-Induced Lens Fiber Differentiation, Investigative Ophthalmology and Visual Science, vol.51, 7, 2010,pp 3599-3610
2004Growth Factors In Lens DevelopmentMcAvoy, Johnston; Lang, Richard A; Central Clinical School: Clinical Ophthal & Eye HealthGrowth Factors In Lens Development in Development of the Ocular Lens, Cambridge University Press, 2004, pp. 261-289
2009Growth factors involved in aqueous humour-induced lens cell proliferationIyengar, L; Lovicu, Frank; McAvoy, Johnston; Patkunanathan, Bramilla; School of Medical Sciences: School of Medical Sciences; School of Medical Sciences: Anatomy & Histology; Central Clinical School: Clinical Ophthal & Eye Health; Deans Unit: (CIPHER)Growth factors involved in aqueous humour-induced lens cell proliferation, Growth Factors, vol.27,(1),2009,pp 50-62
2007In vitro generation of functional lens-like structures with relevance to age-related nuclear cataractMcAvoy, Johnston; O'Connor, M; Central Clinical School: Clinical Ophthal & Eye Health; Central Clinical School: Ophthalmology & Eye HealthIn vitro generation of functional lens-like structures with relevance to age-related nuclear cataract, Investigative Ophthamology and Visual Science (IOVS), vol.48,(3),2007,pp 1245-1252