Browsing by Author Liddle, Christopher

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Issue DateTitleAuthor(s)Citation
2017Aptamer-based therapeutic approaches to target cancer stem cellsBagdesar, Mary; George, Jacob; Hebbard, Lionel; Latchoumanin, Olivier; Liddle, Christopher; Qiao, Liang; Zhou, Gang; Duan, Wei; Westmead Clinical School: Westmead Institute for Medical Res; Westmead Clinical School: Westmead Institute for Medical Res; Westmead Clinical School: Westmead Institute for Medical Res; Westmead Clinical School: Medicine; Westmead Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Westmead Clinical School: MedicineAptamer-based therapeutic approaches to target cancer stem cells, Theranostics, vol.7, 16, 2017,pp 3948-3961
2016Aptamers: A promising chemical antibody for cancer therapyGeorge, Jacob; Liddle, Christopher; Qiao, Liang; Wilson, George; Zhou, Gang; Duan, Wei; Hebbard, Lionel; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead)Aptamers: A promising chemical antibody for cancer therapy, Oncotarget, vol.7, 12, 2016,pp 13446-13463
2014Barx2 and Pax7 Have Antagonistic Functions in Regulation of Wnt Signaling and Satellite Cell DifferentiationLiddle, Christopher; Downes, Michael; Evans, Ronald; Gromova, Anastasia; Hulin, Julie-Ann; Makarenkova, Helen; Meech, Robyn; Nguyen, Thi Diem Tran; Yu, Ruth; Zhuang, Lizhe; Western Clinical School: Medicine (Westmead)Barx2 and Pax7 Have Antagonistic Functions in Regulation of Wnt Signaling and Satellite Cell Differentiation, Stem Cells, vol.32, 6, 2014,pp 1661-1673
2006Benefit of farnesoid X receptor inhibition in obstructive cholestasis.Coulter, Sally; Liddle, Christopher; Stedman, Catherine; Alvarez, Jacqueline G. A.; Downes, Michael; Evans, Ronald M.; Sonoda, Junichiro; School of Medical Sciences: Pharmacology; Western Clinical School: Medicine (Westmead); Clinical SchoolsBenefit of farnesoid X receptor inhibition in obstructive cholestasis., Proceedings of the National Academy of Sciences, vol.103,(30),2006,pp 11323-11328
2014Binding Sites Analyser (BiSA): Software for Genomic Binding Sites Archiving and Overlap AnalysisClarke, Christine; Graham, Justine (Dinny); Khushi, Matloob; Liddle, Christopher; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Children's Hospital Westmead: Medicine; Western Clinical School: Medicine (Westmead)Binding Sites Analyser (BiSA): Software for Genomic Binding Sites Archiving and Overlap Analysis, PloS One, vol.9, 2, 2014,pp 1-12
2015BRD4 is a novel therapeutic target for liver fibrosisLiddle, Christopher; Benner, Chris; Ding, Ning; Downes, Michael; Evans, Ronald Mark; Hah, Nasun; He, Mingxiao; Leblanc, Mathias; Sherman, Mara; Yu, Ruth T; Western Clinical School: Medicine (Westmead)BRD4 is a novel therapeutic target for liver fibrosis, Proceedings of the National Academy of Sciences of the United States of America (PNAS), vol.112, 51, 2015,pp 15713-15718
2015Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic CancerLiddle, Christopher; Arensman, Michael D; Dawson, David W; Downes, Michael; Evans, Ronald; Kershaw, Kathleen M; Lay, Anna R; Nguyen, Phillip; Ostertag-Hill, Claire A; Sherman, Mara; Western Clinical School: Medicine (Westmead)Calcipotriol Targets LRP6 to Inhibit Wnt Signaling in Pancreatic Cancer, Molecular Cancer Research, vol.N/A, N/A, 2015,pp N/A-N/A
2003Changes in Antipyrine Clearance and Platelet Count, but Not Conventional Liver Tests, Correlate With Fibrotic Change in Chronic Hepatitis C: Value for Predicting Fibrotic ProgressionByth Wilson, Karen; Coverdale, Shirley-Ann; Crewe, Evelyn; Farrell, Geoffrey; George, Jacob; Kench, James; Khan, Mahbub; Liddle, Christopher; Lin, Rita; Samarasinghe, Dev; School of Public Health: NH&MRC Clinical Trials Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; School of Medical Sciences: Pathology; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead)Changes in Antipyrine Clearance and Platelet Count, but Not Conventional Liver Tests, Correlate With Fibrotic Change in Chronic Hepatitis C: Value for Predicting Fibrotic Progression, THE AMERICAN JOURNAL OF GASTROENTEROLOGY, vol.98,(6),2003,pp 1384-1390
2002Changes in Serum Albumin During Treatment of Chronic Hepatitis B With Lamivudine: Effects of Response and Emergence of Drug ResistanceFarrell, Geoffrey; George, Jacob; Hui, Jason; Liddle, Christopher; Lin, Rita; Samarasinghe, Dev; Crewe, Evelyn; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Clinical Schools; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead)Changes in Serum Albumin During Treatment of Chronic Hepatitis B With Lamivudine: Effects of Response and Emergence of Drug Resistance, American Journal of Gastroenterology, vol.97,(4),2002,pp 1003-1009
2016Circadian Amplitude Regulation via FBXW7-Targeted REV-ERB(alpha) DegradationLiddle, Christopher; Atkins, Annette; Banayo, Ester; Cho, Han; Chong, L; et al, Various; Han, Xuemei; Hirota, Tsuyoshi; Lamia, Katja; Liu, Sihao; Zhao, Xuan; Western Clinical School: Medicine (Westmead)Circadian Amplitude Regulation via FBXW7-Targeted REV-ERB(alpha) Degradation, Cell, vol.165, 7, 2016,pp 1644-1657
2017Circadian clock cryptochrome proteins regulate autoimmunityLiddle, Christopher; Bai, Jingwen; Cao, Qi; Chen, Qi; Chen, Zhengshan; et al, Various; Gery, Sigal; Lin, De-Chen; Mack, Lauren; Sun, Haibo; Zhao, Xuan; Westmead Clinical School: MedicineCircadian clock cryptochrome proteins regulate autoimmunity, Proceedings of the National Academy of Sciences of the United States of America, vol.114, 47, 2017,pp 12548-12553
2016Cistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseasesBooth, David; Coulter, Sally; Liddle, Christopher; Parnell, Grant; Schibeci, Stephen; Shahijanian, Fernando; Stewart, Graeme; Atkins, Annette; Ding, Ning; Downes, Michael; Evans, Ronald; Western Clinical School: Westmead Institute for Medical Res; School of Medical Sciences: Pharmacology; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Medicine; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical ResCistromic and genetic evidence that the vitamin D receptor mediates susceptibility to latitude-dependent autoimmune diseases, Genes and Immunity, vol.17, 4, 2016,pp 213-219
2015Coherence analysis discriminates between retroviral integration patterns in CD34(+) cells transduced under differing clinical trial conditionsAlexander, Ian; Ginn, Samantha; Liddle, Christopher; et al, Various; Garg, Gagan; Hallwirth, Claus V.; Hetherington, Nicola; Hyman, Jessica; Kramer, Belinda; Malani, Nirav V; Peters, Timothy J; Ruan, Xiaoan; Shahab, Atif; Veeravalli, Lavanya; Childrens Medical Research Institute (CMRI); Childrens Medical Research Institute (CMRI); Western Clinical School: Medicine (Westmead)Coherence analysis discriminates between retroviral integration patterns in CD34(+) cells transduced under differing clinical trial conditions, Molecular Therapy - Methods & Clinical Development, vol.2, N/A, 2015,pp 1-10
2014The CYP27B1 variant associated with increased risk of autoimmune disease is underexpressed in tolerising dendritic cellsBooth, David; Brilot-Turville, Fabienne; Liddle, Christopher; McKay, Fiona Catherine; Shojaei, Maryam; Stewart, Graeme; Batten, Marcel L; Gatt, Prudence; O'Connor, Kate; Parnell, Grant; Schibeci, Stephen; Shahijanian, Fernando; Western Clinical School: Westmead Millennium Institute; Children's Hospital Westmead: Paediatrics & Child Health; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Molecular Bioscience; Western Clinical School: Westmead Millennium InstituteThe CYP27B1 variant associated with increased risk of autoimmune disease is underexpressed in tolerising dendritic cells, Human Molecular Genetics, vol.23, 6, 2014,pp 1425-1434
2002The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancerGoodwin, Bryan; Hodgson, Ecushla; Liddle, Christopher; Chen, Xiaoshuang; Chenevix-Trench, Georgia; Giles, G; Hopper, J; McCredie, M E; Purdie, David M; Spurdle, Amanda B; Medicine; School of Medical Sciences: Pharmacology; Western Clinical School: Medicine (Westmead)The CYP3A4*1B polymorphism has no functional significance and is not associated with risk of breast or ovarian cancer, Pharmacogenetics and Genomics, vol.12,(5),2002,pp 355-366
2004Cyp3A5 Genotype And Midazolam Clearance In Australian Patients Receiving ChemotherapyBalleine, Rosemary; Clarke, Christine; Gurney, Howard; Liddle, Christopher; Wong, Mark; Collins, Michael; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium InstituteCyp3A5 Genotype And Midazolam Clearance In Australian Patients Receiving Chemotherapy, Clinical Pharmacology & Therapeutics, vol.75,(6),2004,pp 529-538
2015Dependence of Hippocampal Function on ERR-Gamma-Regulated Mitochondrial MetabolismLiddle, Christopher; Alaynick, William A.; Auwerx, Johan H.; Barish, Grant D.; Downes, Michael R.; Evans, Ronald Mark; Gage, Fred; Kaufman, Samantha; Leblanc, Mathias; Mu, Yangling; Pankratz, Matthew T.; Pei, Liming; Pfaff, Samuel L.; Tseng, Tiffany W.; Yu, Ruth; Western Clinical School: Medicine (Westmead)Dependence of Hippocampal Function on ERR-Gamma-Regulated Mitochondrial Metabolism, Cell Metabolism, vol.21, 4, 2015,pp 628-636
2015Depletion of fat-resident Treg cells prevents age-associated insulin resistanceLiddle, Christopher; Atkins, Annette; Bapat, Sagar P; Cheng, Albert; et al, Various; Fang, Sungsoon; iu, Sihao; Leblanc, Mathias; Liang, Yuqiong; Suh, Jae Myoung; Zhang, Yang; Zhou, Carmen; Western Clinical School: Medicine (Westmead)Depletion of fat-resident Treg cells prevents age-associated insulin resistance, Nature, vol.528, 7580, 2015,pp 137-141
2016Diverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypesBooth, David; Douglas, Mark; Eslam, Mohammed; George, Jacob; Leung, Reynold; Liddle, Christopher; Najim, Mustafa; Rahme, Antony; van der Poorten, David; Weltman, Martin; White, Rose; Abate, Maria; Adams, Leon Anton; Berg, Thomas; Bugianesi, Elisabetta; Chan, Henry Lik Yuen; Dore, Gregory J.; et al, Various; Irving, William; Mangia, Alessandra; Miele, Luca; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead); Childrens Hospital Westmead: Medicine; Nepean Clinical School: Medicine; Central Clinical School: OfficeDiverse impacts of the rs58542926 E167K variant in TM6SF2 on viral and metabolic liver disease phenotypes, Hepatology, vol.64, 1, 2016,pp 34-46
2009Do medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?Hilmer, Sarah; Le Couteur, David; Liddle, Christopher; Seale, John; Crampton, Roselyn; Northern Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Western Clinical School: Medicine (Westmead); School of Medical Sciences: PharmacologyDo medical courses adequately prepare interns for safe and effective prescribing in New South Wales public hospitals?, Internal Medicine Journal, vol.39, 7, 2009,pp 428-434