Browsing by Author Kefford, Richard (Rick)

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Issue DateTitleAuthor(s)Citation
201318F-labelled fluorodeoxyglucose-positron emission tomography (FDG-PET) heterogeneity of response is prognostic in dabrafenib treated BRAF mutant metastatic melanomaCarlino, Matteo; Haydu, Lauren; Kefford, Richard (Rick); Long, Georgina; Saunders, Catherine; Curtis, C. Martin; Lebowitz, Peter; Menzies, Alexander; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine18F-labelled fluorodeoxyglucose-positron emission tomography (FDG-PET) heterogeneity of response is prognostic in dabrafenib treated BRAF mutant metastatic melanoma, European Journal of Cancer, vol.49, 2, 2013,pp 395-402
2012Absence of Distinguishing Senescence Traits in Human Melanocytic NeviBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Rizos, Helen; Scolyer, Richard; Scurr, Lyndee; Thompson, John; Tran, Sieu; Desilva, Chitra; Haferkamp, Sebastian; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgery; Western Clinical School: Medicine (Westmead)Absence of Distinguishing Senescence Traits in Human Melanocytic Nevi, The Journal of Investigative Dermatology, vol.132, 9, 2012,pp 2226-2234
2014Acneiform eruptions: A common cutaneous toxicity of the MEK inhibitor trametinibAnforth, Rachael; Clements, Arthur; Fernandez Penas, Pablo; Kefford, Richard (Rick); Long, Georgina; Nguyen, Bao; Liu, Michael; Uribe, Pablo; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Nepean Clinical School: MedicineAcneiform eruptions: A common cutaneous toxicity of the MEK inhibitor trametinib, The Australasian Journal of Dermatology, vol.55, 4, 2014,pp 250-254
2015Acquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanismsKefford, Richard (Rick); Long, Georgina; Menzies, Alexander Maxwel; Pupo, Gulietta; Rizos, Helen; Scolyer, Richard; Thompson, John; Becker, Jurgen C; Berking, Carola; Eroglu, Zeynep; et al, Various; Gogas, Helen; Gutzmer, R.; Johnson, Douglas B; Sucker, Antje; Ye, Fei; Zhao, Shilin; Zimmer, Lisa; Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Central Clinical School: Pathology; Central Clinical School: SurgeryAcquired BRAF inhibitor resistance: A multicenter meta-analysis of the spectrum and frequencies, clinical behaviour, and phenotypic associations of resistance mechanisms, European Journal of Cancer, vol.51, 18, 2015,pp 2792-2799
2014Acquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor TherapyKefford, Richard (Rick); Long, Georgina; Chodon, Thinle; Dahlman, Kimberly; et al, Various; Guo, Rongqing; Hong, Aayoung; Hugo, Willy; Johnson, Douglas B; Kong, Xiangju; Koya, Richard; Moriceau, Gatien; Shi, Hubing; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer CentreAcquired Resistance and Clonal Evolution in Melanoma during BRAF Inhibitor Therapy, Cancer Discovery, vol.4, 1, 2014,pp 80-93
2012Acquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK InhibitionBecker, Therese; Gowrishankar, Kavitha; Kefford, Richard (Rick); Pupo, Gulietta; Rizos, Helen; Snoyman, Stephanie; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteAcquired Resistance to BRAF Inhibition Can Confer Cross-Resistance to Combined BRAF/MEK Inhibition, The Journal of Investigative Dermatology, vol.132, 7, 2012,pp 1850-1859
2016Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanomaCarlino, Matteo; Fogarty, Gerald; Guminski, Alexander; Hong, Angela; Kefford, Richard (Rick); Liniker, Elizabeth; Lo, Serigne; Long, Georgina; Menzies, Alexander Maxwel; Ramanujam, Sangeetha; Cooper, Adam; Kong, Benjamin; Wang, T. W.; Western Clinical School: Medicine (Westmead); Northern Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Medicine; Western Clinical School: Medicine (Westmead); Central Clinical School: Melonoma & Skin Cancer Res. Inst.; The George Institute for Global Health; Northern Clinical School: Medicine; Northern Clinical School: Medicine; Central Clinical School: Melonoma & Skin Cancer Res. Inst.Activity and safety of radiotherapy with anti-PD-1 drug therapy in patients with metastatic melanoma, OncoImmunology, vol.5, 9, 2016,pp 1-7
2017Adjuvant dabrafenib plus trametinib in stage III BRAF-mutated melanomaKefford, Richard (Rick); Long, Georgina; Atkinson, Victoria; Chiarion-Sileni, Vanna; Dutriaux, Caroline; et al, Various; Hauschild, Axel; Haydon, Andrew; Larkin, J; MandalĂ , Mario; Nyakas, Marta; Santinami, Mario; Western Clinical School: Medicine (Westmead); Northern Clinical School: MedicineAdjuvant dabrafenib plus trametinib in stage III BRAF-mutated melanoma, New England Journal of Medicine, vol.377, 19, 2017,pp 1813-1823
2010Amino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondriaBecker, Therese; Frausto, Monika; Fung, Carina; Irvine, Malama; Kefford, Richard (Rick); Mijatov, Branka; Philipsz, Suzanah; Rizos, Helen; Gallagher, S. J.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Infectious Diseases; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium InstituteAmino terminal hydrophobic import signals target the p14(ARF) tumor suppressor to the mitochondria, Cell Cycle, vol.9, 4,pp 829-839
2014Anti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trialKefford, Richard (Rick); Boasberg, Peter; Chmielowski, Bartosz; Daud, Adil; Dronca, Roxana; Ebbinghaus, Scot; Elassaiss-Schaap, Jeroen; Gangadhar, Tara C.; Gergich, Kevin; Hamid, Omid; Hodi, F. Stephen; Hwu, Wen-Jen; Iannone, Robert; Joseph, Richard W.; Joshua, Anthony M.; Kang, Peter; Li, Xiaoyun; Mateus, Christine; Patnaik, Amita; Postow, Michael; Ribas, Antoni; Robert, Caroline; Weber, Jeffrey; Wolchok, Jedd D.; Zarour, Hassane; Western Clinical School: Westmead Millennium InstituteAnti-programmed-death-receptor-1 treatment with pembrolizumab in ipilimumab-refractory advanced melanoma: A randomised dose-comparison cohort of a phase 1 trial, The Lancet, vol.384, 9948, 2014,pp 1109-1117
2013Antiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in MelanomaBecker, Therese; Carlino, Matteo; Gowrishankar, Kavitha; Kefford, Richard (Rick); Long, Georgina; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Snoyman, Stephanie; Saunders, Catherine; Zhang, Xu Dong; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteAntiproliferative Effects of Continued Mitogen-Activated Protein Kinase Pathway Inhibition Following Acquired Resistance to BRAF and/or MEK Inhibition in Melanoma, Molecular Cancer Therapeutics, vol.12, 7, 2013,pp 1332-1342
2006The ARF tumour suppressor.Gallagher, Stuart; Kefford, Richard (Rick); Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteThe ARF tumour suppressor., The International Journal of Biochemistry & Cell Biology, vol.38,(10),2006,pp 1637-1641
2015Arthritis and Tenosynovitis Associated With the Anti-PD1 Antibody Pembrolizumab in Metastatic MelanomaCarlino, Matteo; Chan, Matthew; Clements, Arthur; Kefford, Richard (Rick); Manolios, Nicholas; Western Clinical School: Medicine (Westmead); Northern Clinical School: Melanoma Institute of Australia; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Institute for Medical Res; Western Clinical School: Medicine (Westmead)Arthritis and Tenosynovitis Associated With the Anti-PD1 Antibody Pembrolizumab in Metastatic Melanoma, Journal of Immunotherapy, vol.38, 1, 2015,pp 37-39
2006Assocation between circulating white blood cell count and cancer mortality: a population-based cohort study.Kefford, Richard (Rick); Mitchell, Ronald (Paul); Rochtchina, Elina; Wang, Jie Jin; Yu, Mimi; Shankar, Anoop; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Clinical Ophthal & Eye Health; Western Clinical School: Westmead Millennium Institute; MedicineAssocation between circulating white blood cell count and cancer mortality: a population-based cohort study., Archives of Internal Medicine 2005, vol.166,(2),2006,pp 188-194
2003Association of p14ARF with the p120E4F transciptional represssor enhances cell cycle inhibitionBadhwar, Prerna; Becker, Therese; Diefenbach, Eve; Kefford, Richard (Rick); Rizos, Helen; Woodruff, Sarah; Rooney, Robert J.; Medicine; Western Clinical School: Westmead Millennium Institute; Business Liaison Office; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead)Association of p14ARF with the p120E4F transciptional represssor enhances cell cycle inhibition, Journal of Biological Chemistry, vol.278,(7),2003,pp 4981-4989
2002Association of p14ARF with the p120E4F Transcriptional Repressor Enhances Cell Cycle InhibitionBadhwar, Prerna; Becker, Therese; Kefford, Richard (Rick); Rizos, Helen; Diefenbach, Eve; Rooney, Robert J.; Woodruff, Sarah; Medicine; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteAssociation of p14ARF with the p120E4F Transcriptional Repressor Enhances Cell Cycle Inhibition, Journal of Biological Chemistry, vol.278,(7),2002,pp 4981-4989
2013BRAF inhibitor activity in V600R metastatic melanomaClements, Arthur; Kefford, Richard (Rick); Long, Georgina; O'Toole, Sandra; Klein, Oliver; Menzies, Alexander; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: PathologyBRAF inhibitor activity in V600R metastatic melanoma, European Journal of Cancer, vol.49, 5, 2013,pp 1073-1079
2014BRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impactBecker, Therese; Boyd, Suzanah; Carlino, Matteo; Fung, Carina; Haydu, Lauren; Howle, Julie; Kefford, Richard (Rick); Long, Georgina; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Saw, Robyn; Scolyer, Richard; Thompson, John; Hyman, Jessica; Menzies, Alexander; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Infectious Diseases; Central Clinical School: Surgery; Western Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Surgery; Central Clinical School: Pathology; Central Clinical School: SurgeryBRAF inhibitor resistance mechanisms in metastatic melanoma: spectrum and clinical impact, Clinical Cancer Research, vol.20, 7, 2014,pp 1965-1977
2013BRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III MelanomaCampain, Anna; Carter, Candace; De Silva, Chitra; Gerega, Sebastien; Hersey, Peter; Kefford, Richard (Rick); Lai, Kenneth; Mann, Graham; Pianova, Svetlana; Pupo, Gulietta; Schramm, Sarah-Jane; Scolyer, Richard; Synnott, Catherine; Thompson, John; Wilmott, James; Yang, Yee (Jean); Mathematics & Statistics; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Melanoma Foundation; Biological Sciences; Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Clinical Ophthal & Eye Health; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Central Clinical School: Pathology; RADS - Research Analytics & Data Strategy; Central Clinical School: Surgery; Central Clinical School: Surgery; Mathematics & StatisticsBRAF Mutation, NRAS Mutation, and the Absence of an Immune-Related Expressed Gene Profile Predict Poor Outcome in Patients with Stage III Melanoma, The Journal of Investigative Dermatology, vol.133, 2, 2013,pp 509-517
2013BRAF(V600E) protein expression and outcome from BRAF inhibitor treatment in BRAF(V600E) metastatic melanomaHaydu, Lauren; Kefford, Richard (Rick); Long, Georgina; Menzies, Alexander; Scolyer, Richard; Thompson, John; Wilmott, James; Capper, D; Preusser, Matthias; von Diemling, Andreas Von; Zhang, Yuxiao; Central Clinical School: Surgery; Western Clinical School: Westmead Millennium Institute; Central Clinical School: The Sydney Cancer Centre; Central Clinical School: Medicine; Central Clinical School: Pathology; Central Clinical School: Surgery; Central Clinical School: SurgeryBRAF(V600E) protein expression and outcome from BRAF inhibitor treatment in BRAF(V600E) metastatic melanoma, British Journal of Cancer, vol.108, 4, 2013,pp 924-931