Browsing by Author Karim, Nasiara

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Showing results 1 to 17 of 17
Issue DateTitleAuthor(s)Citation
20122'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptorsCollins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Curmi, John; Tierney, Louise; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy2'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors, British Journal of Pharmacology, vol.165, 4, 2012,pp 880-896
20113-Hydroxy-2'-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABBA receptor subtypesCollins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Wellendorph, Petrine; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy3-Hydroxy-2'-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABBA receptor subtypes, Biochemical Pharmacology, vol.82, 12, 2011,pp 1971-1983
2012(alpha)4(beta)(delta) GABAA receptors are high-affinity targets for gamma-hydroxybutyric acid (GHB)Absalom, Nathan; Collins (Chebib), Mary; Karim, Nasiara; Bay, Tina; Brauner-Osborne, Hans; Clausen, Rasmus; Eghorn, Laura; Frolund, Bente; Knudsen, Gitte; Olsen, Jesper; Villumsen, Inge; Wellendorph, Petrine; Pharmacy; Pharmacy; Pharmacy(alpha)4(beta)(delta) GABAA receptors are high-affinity targets for gamma-hydroxybutyric acid (GHB), Proceedings of the National Academy of Sciences (PNAS), vol.109, 33, 2012,pp 13404-13409
2015Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus OfficinalisAbdelhalim, Abeer; Collins, Mary; Hanrahan, Jane; Johnston, Graham; Aburjai, Talal; Karim, Nasiara; Khan, Imran; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyAntidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis, Journal of Pharmacy and Pharmaceutical Sciences, vol.18, 4, 2015,pp 448-459
2015Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus OfficinalisAbdelhalim, Abeer; Collins, Mary; Hanrahan, Jane; Johnston, Graham; Aburjai, Talal; Karim, Nasiara; Khan, Imran; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyAntidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis, Journal of Pharmacy and Pharmaceutical Sciences, vol.18, 4, 2015,pp 448-459
2015Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus OfficinalisAbdelhalim, Abeer; Collins, Mary; Hanrahan, Jane; Johnston, Graham; Aburjai, Talal; Karim, Nasiara; Khan, Imran; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyAntidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis, Journal of Pharmacy and Pharmaceutical Sciences, vol.18, 4, 2015,pp 448-459
2015Antidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus OfficinalisAbdelhalim, Abeer; Collins, Mary; Hanrahan, Jane; Johnston, Graham; Aburjai, Talal; Karim, Nasiara; Khan, Imran; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyAntidepressant, Anxiolytic and Antinociceptive Activities of Constituents from Rosmarinus Officinalis, Journal of Pharmacy and Pharmaceutical Sciences, vol.18, 4, 2015,pp 448-459
2013Covalent trapping of methyllycaconitine at the alpha4-alpha4 interface of the apha4beta2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealedAbsalom, Nathan; Balle, Thomas; Collins (Chebib), Mary; Karim, Nasiara; Qudah, Taima; Quek, Gracia; von Arenstorff, Ida; Ambrus, Joseph; Harps√łe, Kasper; Lewis, Trevor M.; McLeod, Malcolm; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyCovalent trapping of methyllycaconitine at the alpha4-alpha4 interface of the apha4beta2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed, The Journal of Biological Chemistry, vol.288, 37, 2013,pp 26521-26532
2012Flavan-3-ol esters: new agents for exploring modulatory sites on GABAA receptorsCollins (Chebib), Mary; Fernandez, Sebastian; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Mewett, Kenneth; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: PharmacologyFlavan-3-ol esters: new agents for exploring modulatory sites on GABAA receptors, British Journal of Pharmacology, vol.165, 4, 2012,pp 965-977
2016GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica LinnCollins, Mary; Abdelhalim, Abeer; Ahmad, Waqar; Karim, Nasiara; Khan, Imran; PharmacyGABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn, Evidence-Based Complementary and Alternative Medicine, vol.2016, N/A, 2016,pp 1-12
2016GABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica LinnCollins, Mary; Abdelhalim, Abeer; Ahmad, Waqar; Karim, Nasiara; Khan, Imran; PharmacyGABA-A Receptor Modulation and Anticonvulsant, Anxiolytic, and Antidepressant Activities of Constituents from Artemisia indica Linn, Evidence-Based Complementary and Alternative Medicine, vol.2016, N/A, 2016,pp 1-12
2015GABAA receptor modulation and neuropharmacological activities of viscosine isolated from Dodonaea viscosa (Linn)Collins, Mary; Karim, Nasiara; Anis, Itrat; Irshad, Shahid; Khan, Imran; Khan, Inamullah; Mohammad, Akhtar; Shah, Muhammad Raza; Pharmacy; PharmacyGABAA receptor modulation and neuropharmacological activities of viscosine isolated from Dodonaea viscosa (Linn), Pharmacology, Biochemistry and Behavior, vol.136, N/A, 2015,pp 64-72
2011Identification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABAA ReceptorsCollins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyIdentification of Benzopyran-4-one Derivatives (Isoflavones) as Positive Modulators of GABAA Receptors, ChemMedChem: chemistry enabling drug discovery, vol.6, 8, 2011,pp 1340-1346
2012Low nanomolar GABA effects at extrasynaptic a4b1/b3d GABAA receptor subtypes indicate a different binding mode for GABA at these receptorsAbsalom, Nathan; Collins (Chebib), Mary; Hanrahan, Jane; Hansen, Maja; Johnston, Graham; Karim, Nasiara; Lee, Ho Joon; Bang, Line; Jensen, Marianne Lerbech; Wellendorph, Petrine; Pharmacy; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; PharmacyLow nanomolar GABA effects at extrasynaptic a4b1/b3d GABAA receptor subtypes indicate a different binding mode for GABA at these receptors, Biochemical Pharmacology, vol.84, 4, 2012,pp 549-557
2014Modulation of Ionotropic GABA Receptors by 6-Methoxyflavanone and 6-MethoxyflavoneChebib, Mary; Hall, Belinda; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyModulation of Ionotropic GABA Receptors by 6-Methoxyflavanone and 6-Methoxyflavone, Neurochemical Research, vol.39, N/A, 2014,pp 1068-1078
2017Molecular docking and antiamnesic effects of nepitrin isolated from Rosmarinus officinalis on scopolamine-induced memory impairment in miceHanrahan, Jane; Abdelhalim, Abeer; Abdel-Halim, H; Karim, Nasiara; Khan, Imran; PharmacyMolecular docking and antiamnesic effects of nepitrin isolated from Rosmarinus officinalis on scopolamine-induced memory impairment in mice, Biomedicine and Pharmacotherapy, vol.96, N/A, 2017,pp 700-709
2013Potency of gaba at human recombinant gaba alpha receptors expressed in xenopus oocytes: a mini reviewAbsalom, Nathan; Collins (Chebib), Mary; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Wellendorph, Petrine; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyPotency of gaba at human recombinant gaba alpha receptors expressed in xenopus oocytes: a mini review, Amino Acids, vol.44, 4, 2013,pp 1139-1149