Browsing by Author Holst, Jeffrey

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Issue DateTitleAuthor(s)Citation
2017Adipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migrationBalaban, Seher; Cairns, Rose; Fazakerley, Daniel; Grewal, Thomas; Holst, Jeffrey; Hoy, Andrew; Lee, Lisa; Schreuder, Mark; Shtein, Harrison; Thomas, Kristen; van Geldermalsen, Michelle; Saunders, Darren N.; Shearer, Robert F.; School of Medical Sciences: Physiology; School of Medical Sciences: Pharmacology; School of Molecular Bioscience (SMB); Pharmacy; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; School of Medical Sciences: Physiology; School of Medical Sciences: Physiology; School of Medical Sciences: Brain and Mind Centre; School of Life and Environmental Sciences (SOLES); Central Clinical School: Centenary InstituteAdipocyte lipolysis links obesity to breast cancer growth: adipocyte-derived fatty acids drive breast cancer cell proliferation and migration, Cancer and Metabolism, vol.5, 1, 2017,pp N/A-N/A
2011Androgen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer ProgressionBailey, Charles; Holst, Jeffrey; Rasko, John; Buchanan, Grant; Hendy, Stephen; Lehman, Melanie; Minhas, Vineet; Nelson, Colleen; Ng, Cynthia; Thoeng, Annora; Tiffen, Jessamy; Wang, Qian; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteAndrogen Receptor and Nutrient Signaling Pathways Coordinate the Demand for Increased Amino Acid Transport during Prostate Cancer Progression, Cancer Research, vol.71, 24, 2011,pp 7525-7536
2017The antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivoBailey, Charles; Gao, Dadi; Guan, Fiona Hui Xian; Holst, Jeffrey; Khoo, Teh-Liane; Metierre, Cynthia; O'Young, Patrick; Rasko, John; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe antiproliferative ELF2 isoform, ELF2B, induces apoptosis in vitro and perturbs early lymphocytic development in vivo, Journal of Hematology and Oncology, vol.10, 1, 2017,pp 1-17
2017ASCT2 regulates glutamine uptake and cell growth in endometrial carcinomaAnderson, Lyndal; Holst, Jeffrey; Marshall, Amy; Nagarajah, Rajini; Otte, N; Pang, Angel; Rasko, John; Thoeng, Annora; van Geldermalsen, Michelle; Vellozzi, Melissa; Wang, Kevin Qian; Zhang, Blake; Lum, Trina; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; Central Clinical School: Centenary Institute; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteASCT2 regulates glutamine uptake and cell growth in endometrial carcinoma, Oncogenesis, vol.6, N/A, 2017,pp 1-10
2018Benzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathwaysFreidman, Natasha; Guan, Yi; Holst, Jeffrey; Krycer, James; Pang, Angel; Quek, Lake-Ee; Ryan, Renae; Van Geldermalsen, Michelle; Wang, Qian; Turner, Nigel; School of Medical Sciences: Pharmacology; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; School of Life and Environmental Sciences (SOLES); Central Clinical School: Centenary Institute; Mathematics & Statistics; School of Medical Sciences: Pharmacology; Medicine; Clinical NursingBenzylserine inhibits breast cancer cell growth by disrupting intracellular amino acid homeostasis and triggering amino acid response pathways, BMC Cancer, vol.18, 1, 2018,pp 689 - 1-689 - 14
2016Bioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularisHolst, Jeffrey; Wang, Qian; Davis, Rohan A; Healy, Peter C.; Hofmann, Andreas; Levrier, Claire; Nelson, Colleen; Sadowski, Martin C; Wibowo, Mario; Central Clinical School: Centenary Institute; Clinical NursingBioactive Dihydro-β-agarofuran Sesquiterpenoids from the Australian Rainforest Plant Maytenus bilocularis, Journal of Natural Products, vol.79, 5, 2016,pp 1445-1453
2013The cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cellsBailey, Charles; Feng, Yue; Holst, Jeffrey; Marshall, Amy; Metierre, Cynthia; Rasko, John; Tiffen, Jessamy; Wang, Qian; Watson, Sarah L.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe cancer-testis antigen BORIS phenocopies the tumor suppressor CTCF in normal and neoplastic cells, International Journal of Cancer, vol.133, 7, 2013,pp 1603-1613
2017Celastrofurans A-G: Dihydro-(beta)-Agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer CellsHolst, Jeffrey; Wang, Kevin Qian; Davis, R; Hofmann, Andreas; White, Jonathan M; Wibowo, M; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteCelastrofurans A-G: Dihydro-(beta)-Agarofurans from the Australian Rainforest Vine Celastrus subspicata and Their Inhibitory Effect on Leucine Transport in Prostate Cancer Cells, Journal of Natural Products, vol.80, 6, 2017,pp 1918-1925
2016Dihydro-B-agarofurans from the Australian Endemic Rainforest Plant Denhamia pittosporoides Inhibit Leucine Transport in Prostate Cancer CellsHolst, Jeffrey; Wang, Qian; Davis, Rohan A; Hofmann, Andreas; White, Jonathan M; Wibowo, Mario; Central Clinical School: Centenary Institute; Clinical NursingDihydro-B-agarofurans from the Australian Endemic Rainforest Plant Denhamia pittosporoides Inhibit Leucine Transport in Prostate Cancer Cells, Asian Journal of Organic Chemistry, vol.5, 12, 2016,pp 1461-1466
2012The Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemiaCatchpoole, Daniel; Holst, Jeffrey; Ardjmand, A; Bone, S; Campbell, D; de Bock, C E; et al, various; Johnstone, Daniel; Molloy, T; Nelmes, G; Shipman, Kristy L.; Spanevello, Mark; Yeadon, Trina; Children's Hospital Westmead: Paediatrics & Child Health; Central Clinical School: Centenary InstituteThe Fat1 cadherin is overexpressed and an independent prognostic factor for survival in paired diagnosis-relapse samples of precursor B-cell acute lymphoblastic leukemia, Leukemia, vol.26, 5, 2012,pp 918-926
2016Guttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradationDong, Qihan; Holst, Jeffrey; Xie, Chanlu; Yao, Mu; Cai, S.; Lao, Y.; Li, Y.; Liu, T; Tan, H.; Xi, Z.; Xu, H-X.; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: MedicineGuttiferone K impedes cell cycle re-entry of quiescent prostate cancer cells via stabilization of FBXW7 and subsequent c-MYC degradation, Cell Death and Disease, vol.7, 6, 2016,pp 1-13
2014Identification of nuclear-enriched miRNAs during mouse granulopoiesisGao, Dadi; Gonzalez, Maria; Holst, Jeffrey; Lau, Katherine; Rasko, John; Ritchie, William; Wong, Justin; Choudhary, Anupma; Taft, Ryan J; Central Clinical School: Medicine; Medicine; Central Clinical School: Centenary Institute; Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteIdentification of nuclear-enriched miRNAs during mouse granulopoiesis, Journal of Hematology & Oncology, vol.7, 1, 2014,pp 1-15
2011Impaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient MouseBailey, Charles; Holst, Jeffrey; Rasko, John; Broer, Angelika; Broer, Stefan; Juelich, Torsten; Solomon, Peter S.; Tietze, Nadine; Vanslambrouck, Jessica; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteImpaired Nutrient Signaling and Body Weight Control in a Na+ Neutral Amino Acid Cotransporter (Slc6a19)-deficient Mouse, The Journal of biological chemistry, vol.286, 30, 2011,pp 26638-26651
2017Intron retention is regulated by altered MeCP2-mediated splicing factor recruitmentGao, Dadi; Holst, Jeffrey; Kwok, Chau-To; Middleton, Rob; Nagarajah, Rajini; Nguyen, Trung V; Pinello, Natalia; Rasko, John; Ritchie, William; Thoeng, Annora; Van Geldermalsen, Michelle; Wong, Justin; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Medicine; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Centenary Institute; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; Medicine; Central Clinical School: Centenary InstituteIntron retention is regulated by altered MeCP2-mediated splicing factor recruitment, Nature Communications, vol.8, N/A, 2017,pp 1-13
2015L-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasiaHolst, Jeffrey; Wang, Kevin Qian; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteL-type amino acid transport and cancer: targeting the mTORC1 pathway to inhibit neoplasia, American Journal of Cancer Research, vol.5, 4, 2015,pp 1281-1294
2015LAT Transport Inhibitors from Pittosporum venulosum Identified by NMR Fingerprint AnalysisHolst, Jeffrey; Wang, Kevin Qian; Grkovic, Tanja; Guymer, Gordon P; Pouwer, Rebecca; Quinn, Ronald; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLAT Transport Inhibitors from Pittosporum venulosum Identified by NMR Fingerprint Analysis, Journal of Natural Products, vol.78, 6, 2015,pp 1215-1220
2016LAT1 is a putative therapeutic target in endometrioid endometrial carcinomaAnderson, Lyndal; Holst, Jeffrey; Marshall, Amy; Otte, Nicholas; Rasko, John; Thoeng, Annora; van Geldermalsen, Michelle; Vellozzi, Melissa; Wang, Kevin Qian; Zhang, Blake; Lum, M; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; Central Clinical School: Centenary Institute; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLAT1 is a putative therapeutic target in endometrioid endometrial carcinoma, International Journal of Cancer, vol.139, 11, 2016,pp 2529-2539
2016LAT1 is a putative therapeutic target in endometrioid endometrial carcinomaAnderson, Lyndal; Holst, Jeffrey; Marshall, Amy; Otte, Nicholas; Rasko, John; Thoeng, Annora; van Geldermalsen, Michelle; Vellozzi, Melissa; Wang, Kevin Qian; Zhang, Blake; Lum, M; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; Central Clinical School: Centenary Institute; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLAT1 is a putative therapeutic target in endometrioid endometrial carcinoma, International Journal of Cancer, vol.139, 11, 2016,pp 2529-2539
2015Ligand Discovery for the Alanine-SerineCysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual ScreeningHolst, Jeffrey; Otte, Nicholas; Albers, Thomas; Bonomi, Massimiliano; Colas, Claire; Gameiro, Armanda; Grewer, Christof; Schlessinger, Avner; Shere, Helen; Singh, Kurnvir; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLigand Discovery for the Alanine-SerineCysteine Transporter (ASCT2, SLC1A5) from Homology Modeling and Virtual Screening, PLoS Computational Biology, vol.11, 10, 2015,pp 1-22
2010Luciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivoBailey, Charles; Holst, Jeffrey; Ng, Cynthia; Rasko, John; Tiffen, Jessamy; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLuciferase expression and bioluminescence does not affect tumor cell growth in vitro or in vivo, Molecular Cancer, vol.9, N/A,pp 299-1-299-8