Browsing by Author Hambley, Trevor

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Issue DateTitleAuthor(s)Citation
2008[(1)H, (15)N] Heteronuclear Single Quantum Coherence NMR Study of the Mechanism of Aquation of Platinum(IV) Ammine ComplexesHall, Matthew; Hambley, Trevor; Berners-Price, S; Davies, Murray S; Chemistry; Chemistry[(1)H, (15)N] Heteronuclear Single Quantum Coherence NMR Study of the Mechanism of Aquation of Platinum(IV) Ammine Complexes, Inorganic Chemistry, vol.47, 17, 2008,pp 7673-7680
2009Accumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: The effect of charge on drug distribution in solid tumour modelsBryce, Nicole; Hambley, Trevor; Whan, Renee; Yamamoto, Natsuho; Zhang, Jenny Zhenqi; Chemistry; Chemistry; Electron Microscope; Chemistry; ChemistryAccumulation of an anthraquinone and its platinum complexes in cancer cell spheroids: The effect of charge on drug distribution in solid tumour models, Chemical Communications, vol.2009,(19),2009,pp 2673-2675
2007Basis for design and development of platinum(IV) anticancer complexesHall, Matthew; Hambley, Trevor; Callaghan, Richard; Mellor, Howard R; Chemistry; ChemistryBasis for design and development of platinum(IV) anticancer complexes, Journal of Medicinal Chemistry, vol.50,(15),2007,pp 3403-3411
2009Binding of [Pt(1C3)(dien)]2+ to the duplex DNA oligonucleotide 5'-d(TGGCCA)-3': The effect of an appended positive charge on the orientation and location of anthraquinone intercalationHambley, Trevor; Messerle, Barbara; Whan, Renee; Chemistry; Chemistry; Engineering Faculty AdminBinding of [Pt(1C3)(dien)]2+ to the duplex DNA oligonucleotide 5'-d(TGGCCA)-3': The effect of an appended positive charge on the orientation and location of anthraquinone intercalation, Dalton Transactions: an international journal of inorganic, organometallic and bioinorganic chemistry, vol.2009, 6, 2009,pp 932-939
2007Bioreductive activation and drug chaperoning in cobalt pharmaceuticalsFailes, Timothy; Hall, Matthew; Hambley, Trevor; Yamamoto, Natsuho; Chemistry; Chemistry; Chemistry; ChemistryBioreductive activation and drug chaperoning in cobalt pharmaceuticals, Dalton Transactions, vol.N/A,(36),2007,pp 3983-3990
2001Calculation of the hydrophobicity of platinum drugsHall, Matthew; Hambley, Trevor; Hibbs, David; Platts, J; Chemistry; Chemistry; PharmacyCalculation of the hydrophobicity of platinum drugs, Journal of Medicinal Chemistry, vol.44,(3),2001,pp 472-474
2003Cationic iridium(I) complexes as catalysts for the alcoholysis of silanesField, Leslie; Hambley, Trevor; Soler, Linnea; Messerle, Barbara A; Rehr, Manuela; Chemistry; Chemistry; ChemistryCationic iridium(I) complexes as catalysts for the alcoholysis of silanes, Organometallics, vol.22,(12),2003,pp 2387-2395
2008Cellular uptake and distribution of cobalt complexes of fluorescent ligandsBonnitcha, Paul; Danos, Sarah; Failes, Timothy; Hambley, Trevor; New, Elizabeth; Yamamoto, Natsuho; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryCellular uptake and distribution of cobalt complexes of fluorescent ligands, Journal of Biological Inorganic Chemistry, vol.13,(6),2008,pp 861-871
2002Cis-[PtCl2(NH3){2-(2-hydroxyethyl)pyridine}] - an Analogue of the Anticancer Drug AMD473: Unusual Hydrolysis Rates and pKa Values for the Diaqua AdductHambley, Trevor; Munk, Vivienne; Chen, Yu; Hotze, Anna C G; Kratochwil, Nicole A; Parkinson, John A; Parsons, Simon; Sadler, Peter J; Chemistry; ChemistryCis-[PtCl2(NH3){2-(2-hydroxyethyl)pyridine}] - an Analogue of the Anticancer Drug AMD473: Unusual Hydrolysis Rates and pKa Values for the Diaqua Adduct, European Journal of Inorganic Chemistry, vol.2002,(5),2002,pp 1035-1039
2012Cobalt complexes with tripodal ligands: Implications for the design of drug chaperonesBonnitcha, Paul; Clegg, Jack; Hambley, Trevor; Hocking, Rosalie; Kim, Byung; Neville, Suzanne; Turner, Peter; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryCobalt complexes with tripodal ligands: Implications for the design of drug chaperones, Dalton Transactions: an international journal of inorganic, organometallic and bioinorganic chemistry, vol.41, 37, 2012,pp 11293-11304
2015Cobalt(III) chaperone complexes of curcumin: Photoreduction, cellular accumulation and light-selective toxicity towards tumour cellsHambley, Trevor; Renfrew, Anna; Bryce, Nicole S.; Chemistry; ChemistryCobalt(III) chaperone complexes of curcumin: Photoreduction, cellular accumulation and light-selective toxicity towards tumour cells, Chemistry - A European Journal, vol.21, 43, 2015,pp 15224-15234
2004Comparative Efficacy Of Novel Platinum(IV) Compounds With Established Chemotherapeutic Drugs In Solid Tumour ModelsHall, Matthew; Hambley, Trevor; Callaghan, Richard; Ferguson, David; Martin, Catherine; Phillips, Roger M; Chemistry; ChemistryComparative Efficacy Of Novel Platinum(IV) Compounds With Established Chemotherapeutic Drugs In Solid Tumour Models, Biochemical Pharmacology, vol.67,(1),2004,pp 17-30
2013The composition and end-group functionality of sterically stabilized nanoparticles enhances the effectiveness of co-administered cytotoxinsBryce, Nicole; Fong, Nicole; Hambley, Trevor; Hawkett, Brian; Jain, Nirmesh; Pan, Eh; Pham, Thi; Whan, Renee M.; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryThe composition and end-group functionality of sterically stabilized nanoparticles enhances the effectiveness of co-administered cytotoxins, Journal of Biomaterials Science. Polymer Edition, vol.1, 12, 2013,pp 1260-1272
2004Copper And Zinc Complexes As Antiinflammatory DrugsDillon, Carolyn; Hambley, Trevor; Kennedy, Brendan; Lay, Peter; Weder, Jane; Zhou, Qingdi; Chemistry; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryCopper And Zinc Complexes As Antiinflammatory Drugs in Metal Ions in Biological Systems : Volume 41 : Metal Ions and their Complexes in Medication, Marcel Dekker Inc, 2004, pp. 253-277
2002Copper complexes of non-steroidal anti-inflammatory drugs: an opportunity yet to be realizedDavies, Neal; Dillon, Carolyn; Hambley, Trevor; Kennedy, Brendan; Lay, Peter; Weder, Jane; Biffin, J. Ray; Regtop, Hubert L.; Pharmacy; Chemistry; Chemistry; Chemistry; Chemistry; ChemistryCopper complexes of non-steroidal anti-inflammatory drugs: an opportunity yet to be realized, Coordination Chemistry Reviews, vol.232, 1-2,pp 95-126
2006Cytotoxic efficacy of an anthraquinone linked platinum anticancer drugAlderden, Rebecca; Hambley, Trevor; Callaghan, Richard; Mellor, Howard R; Modok, S; Chemistry; ChemistryCytotoxic efficacy of an anthraquinone linked platinum anticancer drug, Biochemical Pharmacology, vol.71,(8),2006,pp 1136-1145
2007Database analysis of transition metal carbonyl bond lengths: Insight into the periodicity of pi back-bonding, sigma donation, and the factors affecting the electronic structure of the TM-C=O moietyHambley, Trevor; Hocking, Rosalie; Chemistry; ChemistryDatabase analysis of transition metal carbonyl bond lengths: Insight into the periodicity of pi back-bonding, sigma donation, and the factors affecting the electronic structure of the TM-C=O moiety, Organometallics, vol.26,(11),2007,pp 2815-2823
2013Delivery and release of curcumin by a hypoxia-activated cobalt chaperone: a XANES and FLIM studyBryce, Nicole; Hambley, Trevor; Renfrew, Anna; Chemistry; Chemistry; ChemistryDelivery and release of curcumin by a hypoxia-activated cobalt chaperone: a XANES and FLIM study, Chemical Science, vol.4, 9, 2013,pp 3731-3739
2007Developing new metal-based therapeutics: Challenges and opportunitiesHambley, Trevor; ChemistryDeveloping new metal-based therapeutics: Challenges and opportunities, Dalton Transactions, vol.2007,(43),2007,pp 4929-4937
2007DFT study of the systematic variations in metal-ligand bond lengths of coordination complexes: The crucial role of the condensed phaseHambley, Trevor; Hocking, Rosalie; Deeth, Robert J; Chemistry; ChemistryDFT study of the systematic variations in metal-ligand bond lengths of coordination complexes: The crucial role of the condensed phase, Inorganic Chemistry, vol.46,(20),2007,pp 8238-8244