Browsing by Author Gallagher, Stuart

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Issue DateTitleAuthor(s)Citation
2006The ARF tumour suppressor.Gallagher, Stuart; Kefford, Richard (Rick); Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteThe ARF tumour suppressor., The International Journal of Biochemistry & Cell Biology, vol.38,(10),2006,pp 1637-1641
2013The BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistanceGallagher, Stuart; Haass, Nikolas; Hersey, Peter; Mijatov, Branka; Lai, Fritz; Mohana-Kumara, Nethia; Wroblewski, David; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Central Clinical School: Centenary Institute; Northern Clinical School: Surgery; Western Clinical School: Westmead Millennium InstituteThe BH3-mimetic ABT-737 sensitizes human melanoma cells to apoptosis induced by selective BRAF inhibitors but does not reverse acquired resistance, Carcinogenesis, vol.34, 2, 2013,pp 237-247
2015Combining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signalingDe Paoli-Iseppi, Ricardo; Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Strbenac, Dario; Tiffen, Jessamy; Wilmott, James; Yang, Jean Yee Hwa; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Mathematics & Statistics; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Mathematics & StatisticsCombining BET and HDAC inhibitors synergistically induces apoptosis of melanoma and suppresses AKT and YAP signaling, Oncotarget, vol.6, 25, 2015,pp 21507-21521
2014Control of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151Gallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; James, Wilmott; McArthur, Grant A.; Tummino, Peter J; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteControl of NF-kB activity in human melanoma by bromodomain and extra-terminal protein inhibitor I-BET151, Pigment Cell & Melanoma Research, vol.27, 6, 2014,pp 1126-1137
2005Enforced expression of p14ARF induces p53-dependent cell cycle arrest but not apoptosis.Gallagher, Stuart; Kefford, Richard (Rick); Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteEnforced expression of p14ARF induces p53-dependent cell cycle arrest but not apoptosis., Cell Cycle 2005, vol.4,(3),2005,pp 465-472
2017Epigenetic modulation in cancer immunotherapyGallagher, Stuart; Hersey, Peter; Shklovskaya, Elena; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteEpigenetic modulation in cancer immunotherapy, Current Opinion in Pharmacology, vol.35, N/A, 2017,pp 48-56
2014The Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma CellsGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Jin, Lei; Mijatov, Branka; Pupo, Gulietta; Rizos, Helen; Tiffen, Jessamy; Cullinane, Carleen; McArthur, Grant A.; Prinjha, Rab; Smithers, Nicholas; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Central Clinical School: Centenary InstituteThe Epigenetic Regulator I-BET151 Induces BIM Dependent Apoptosis and Cell Cycle Arrest OF Human Melanoma Cells, Journal of Investigative Dermatology, vol.134, 11, 2014,pp 1523-1747
2016EZH2 as a mediator of treatment resistance in melanomaFazekas de St Groth, Barbara Denise; Gallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Tseng, Hsin-Yi; Filipp, Fabian; School of Medical Sciences: Pathology; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: Sydney Melanoma UnitEZH2 as a mediator of treatment resistance in melanoma, Pigment Cell & Melanoma Research, vol.29, 5, 2016,pp 500-507
2015EZH2: An emerging role in melanoma biology and strategies for targeted therapyGallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteEZH2: An emerging role in melanoma biology and strategies for targeted therapy, Pigment Cell & Melanoma Research, vol.28, 1, 2015,pp 21-30
2013A Focus on PD-L1 in Human MelanomaGallagher, Stuart; Hersey, Peter; Western Clinical School: Medicine (Westmead); Northern Clinical School: SurgeryA Focus on PD-L1 in Human Melanoma, Clinical Cancer Research, vol.19, 3, 2013,pp 514-516
2018HDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanomaBeaumont, Kimberley; Ferguson, Peter; Gallagher, Stuart; Gunatilake, Dilini; Haass, Nikolas; Heinemann, Anja; Hersey, Peter; Madore, Jason; Rizos, Helen; Sharp, Danae; Tiffen, Jessamy; Weninger, Wolfgang; Wilmott, James; Central Clinical School: Centenary Institute; Medicine; Westmead Clinical School: Medicine; Northern Clinical School: Kolling Institute; Central Clinical School: Centenary Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Medicine; Westmead Clinical School: Westmead Institute for Medical Res; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: SurgeryHDAC inhibitors restore BRAF-inhibitor sensitivity by altering PI3K and survival signalling in a subset of melanoma, International Journal of Cancer, vol.142, 9, 2018,pp 1926-1937
2012Histone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF InhibitorsGallagher, Stuart; Hersey, Peter; Jin, Lei; Mijatov, Branka; Lai, Fritz; Zhang, Xu Dong; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Northern Clinical School: Kolling Institute; Western Clinical School: Westmead Millennium InstituteHistone Deacetylases (HDACs) as Mediators of Resistance to Apoptosis in Melanoma and as Targets for Combination Therapy with Selective BRAF Inhibitors, Advances in Pharmacology, vol.65, N/A, 2012,pp 27-43
2015Histone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune TherapyGallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteHistone Modifications, Modifiers and Readers in Melanoma Resistance to Targeted and Immune Therapy, Cancers, vol.7, 4, 2015,pp 1959-1982
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2015Inducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?BGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Hersey, Peter; Tiffen, Jessamy; Rizos, Helen; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteInducible but not constitutive expression of PD-L1 in human melanoma cells is dependent on activation of NF-?B, PloS One, vol.10, 4, 2015,pp 1-19
2014Intralesional immunotherapy for melanomaGallagher, Stuart; Hersey, Peter; Western Clinical School: Medicine (Westmead); Northern Clinical School: SurgeryIntralesional immunotherapy for melanoma, Journal of Surgical Oncology, vol.109, 4, 2014,pp 320-326
2008p16INK4a expression and absence of activated B-RAF are independent predictors of chemosensitivity in melanoma tumorsDunleavey, Ruth; Gallagher, Stuart; Gao, Bo-Fu; Indsto, James; Kefford, Richard (Rick); Mann, Graham; Rizos, Helen; Scurr, Lyndee; Thompson, John; Lett, Margaret; Western Clinical School (Westmead): Office; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Central Clinical School: Surgeryp16INK4a expression and absence of activated B-RAF are independent predictors of chemosensitivity in melanoma tumors, NeoPlasia: an international journal of oncology research, vol.10, 11, 2008,pp 1231-1239
2016Somatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in MelanomaGallagher, Stuart; Hersey, Peter; Tiffen, Jessamy; Filipp, Fabian; Wilson, Stephen; Western Clinical School: Medicine (Westmead); Northern Clinical School: Surgery; Central Clinical School: Centenary InstituteSomatic Copy Number Amplification and Hyperactivating Somatic Mutations of EZH2 Correlate With DNA Methylation and Drive Epigenetic Silencing of Genes Involved in Tumor Suppression and Immune Responses in Melanoma, NeoPlasia: an international journal of oncology research, vol.18, 2, 2016,pp 121-132
2015Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genesGallagher, Stuart; Gowrishankar, Kavitha; Gunatilake, Dilini; Heinemann, Anja; Hersey, Peter; Madore, Jason; Mann, Graham; Pupo, Gulietta; Strbenac, Dario; Tiffen, Jessamy; Yang, Jean Yee Hwa; Cullinane, Carleen; Dutton-Regester, Ken; Filli[, Fabian V.; Hayward, Nicholas; McArthur, Grant A.; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); Northern Clinical School: Kolling Institute; Northern Clinical School: Kolling Institute; Northern Clinical School: Surgery; Central Clinical School: Melonoma & Skin Cancer Res. Inst.; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Medicine (Westmead); Mathematics & Statistics; Central Clinical School: Centenary Institute; Mathematics & StatisticsTargeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes, Oncotarget, vol.6, 29, 2015,pp 27023-27036