Browsing by Author Doddareddy, Munikumar

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Showing results 1 to 14 of 14
Issue DateTitleAuthor(s)Citation
2013Alanine Scan of an Immunosuppressive Peptide (CP): Analysis of Structure-Function RelationshipsAli, Marina; Bender, Veronika; Doddareddy, Munikumar; Hibbs, David; Manolios, Nicholas; Raguine, Laura; Diefenbach, Eve; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead); School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Western Clinical School: Medicine (Westmead); Western Clinical School: Medicine (Westmead)Alanine Scan of an Immunosuppressive Peptide (CP): Analysis of Structure-Function Relationships, Chemical Biology & Drug Design, vol.81, 2, 2013,pp 167-174
2012Antiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2Bourget, Kirsi; Cui, Pei (Sarah); Doddareddy, Munikumar; Duke, Colin; Hibbs, David; Kim, Terry; Murray, Michael; Rawling, Tristan; Tattam, Bruce; Zhou, Fanfan; Petrovic, Nenad; Pharmacy; Pharmacy; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyAntiproliferative and Antimigratory Actions of Synthetic Long Chain n-3 Monounsaturated Fatty Acids in Breast Cancer Cells That Overexpress Cyclooxygenase-2, Journal of Medicinal Chemistry, vol.55, 16, 2012,pp 7163-7172
2017A Carbocyclic Curcumin Inhibits Proliferation of Gram-Positive Bacteria by Targeting FtsZDoddareddy, Munikumar; Groundwater, Paul; Hibbs, David; Liao, Vivian; Mamidi, Ramesh; Narlawar, Rajeshwar; Oza, P; Bhattacharya, A; Kunal, K; Marrs, Emma C. L.; Panda, Dulal; Perry, J; Srivastava, S; School of Medical Sciences: Brain and Mind Centre; Pharmacy; Pharmacy; Central Clinical School: Medicine; Pharmacy; Pharmacy; PharmacyA Carbocyclic Curcumin Inhibits Proliferation of Gram-Positive Bacteria by Targeting FtsZ, Biochemistry, vol.56, 3, 2017,pp 514-524
2013Design, synthesis, and pharmacological evaluation of fluorescent and biotinylated antagonists of P1 GABA(c) receptorsCollins (Chebib), Mary; Doddareddy, Munikumar; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Kim, Hye-Lim; Pharmacy; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyDesign, synthesis, and pharmacological evaluation of fluorescent and biotinylated antagonists of P1 GABA(c) receptors, A C S Medicinal Chemistry Letters, vol.4, 4, 2013,pp 402-407
2013The development of CNS-active LRRK2 inhibitors using property-directed optimisationDoddareddy, Munikumar; Kassiou, Michael; Kavanagh, Madeline; School of Medical Sciences: Brain & Mind Research Institute; Medical Imaging and Radiation Sciences; ChemistryThe development of CNS-active LRRK2 inhibitors using property-directed optimisation, Bioorganic & Medicinal Chemistry Letters, vol.23, 13, 2013,pp 3690-3696
2012Differentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABAC rho1 ReceptorsAbsalom, Nathan Luke; Carland, Jane; Collins, Mary; Doddareddy, Munikumar; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Yamamoto, Izumi; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Brain and Mind Centre; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyDifferentiating Enantioselective Actions of GABOB: A Possible Role for Threonine 244 in the Binding Site of GABAC rho1 Receptors, ACS Chemical Neuroscience, vol.3, 9, 2012,pp 665-673
2013The discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonistsDoddareddy, Munikumar; Gavande, Navnath; Groundwater, Paul; Hibbs, David; Matin, Azadeh; Roubin, Rebecca; Nammi, Srinivas; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyThe discovery of novel isoflavone pan peroxisome proliferator-activated receptor agonists, Bioorganic and Medicinal Chemistry: the tetrahedron journal for research at the interface of chemistry and biology, vol.21, 3, 2013,pp 766-778
2012The enantiomers of syn-2,3-difluoro-4-aminobutyric acid elicit opposite responses at the GABA(C) receptorCollins (Chebib), Mary; Doddareddy, Munikumar; Gavande, Navnath; Hunter, Luke; Jordan, Meredith; Yamamoto, Izumi; Pharmacy; Brand Management; Pharmacy; Chemistry; Chemistry; PharmacyThe enantiomers of syn-2,3-difluoro-4-aminobutyric acid elicit opposite responses at the GABA(C) receptor, Chemical Communications, vol.48, 6, 2012,pp 829-831
2012Exploration of ring size in a series of cyclic vicinal diamines with sigma(1) receptor-affinityBanister, Samuel; Doddareddy, Munikumar; Kassiou, Michael; Manoli, Miral; Moussa, Iman; Cui, Jinquan; Mach, Robert H.; Chemistry; Brand Management; Medical Imaging and Radiation Sciences; Medical Radiation Sciences; ChemistryExploration of ring size in a series of cyclic vicinal diamines with sigma(1) receptor-affinity, Bioorganic & Medicinal Chemistry Letters, vol.22, 17, 2012,pp 5493-5497
2015Optimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammationChen, Ew-Jun; Doddareddy, Munikumar; Kassiou, Michael; Kavanagh, Madeline; Munoz, Lenka; Phoa, Athena; Dzamko, Nicolas; Guillemin, Gilles J.; Heng, Benjamin; Not known; School of Medical Sciences: Brain & Mind Research Institute; Medical Imaging and Radiation Sciences; Chemistry; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyOptimisation of LRRK2 inhibitors and assessment of functional efficacy in cell-based models of neuroinflammation, European Journal of Medicinal Chemistry, vol.95, N/A, 2015,pp 29-34
2015Potentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cellsDoddareddy, Munikumar; Fordham, Ashleigh; Hibbs, David; Huang, Michael; Kalinowski, Danuta; Lane, Darius John Rowland; Merlot, Angelica; Ong, Jennifer; Pantarat, Namfon; Richardson, Desi (Des); Richardson, Vera; Sahni, Sumit; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Bosch Institute; Pharmacy; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Bosch Institute; Pharmacy; Western Clinical School: Westmead Institute for Medical Res; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyPotentiating the cellular targeting and anti-tumor activity of Dp44mT via binding to human serum albumin: two saturable mechanisms of Dp44mT uptake by cells, Oncotarget, vol.6, 12, 2015,pp 10374-10398
2012Role of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolitesCui, Pei (Sarah); Doddareddy, Munikumar; Ghassabian, Susan; Hibbs, David; Murray, Michael; Rawling, Tristan; Tattam, Bruce; Zhou, Fanfan; Edwards, Robert J.; Pharmacy; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyRole of human CYP3A4 in the biotransformation of sorafenib to its major oxidized metabolites, Biochemical Pharmacology, vol.84, 2, 2012,pp 215-223
2012Targeting mitogen-activated protein kinase phosphatase-1 (MKP-1): structure-based design of MKP-1 inhibitors and upregulatorsAmmit, Alaina; Doddareddy, Munikumar; Rawling, Tristan; Central Clinical School: Woolcock Inst. of Medical Research; School of Medical Sciences: Brain and Mind Centre; PharmacyTargeting mitogen-activated protein kinase phosphatase-1 (MKP-1): structure-based design of MKP-1 inhibitors and upregulators, Current Medicinal Chemistry, vol.19, 2, 2012,pp 163-173
2012A σ1 receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDS)Banister, Samuel; Doddareddy, Munikumar; Hibbs, David; Kassiou, Michael; Manoli, Miral; Chemistry; Brand Management; Pharmacy; Medical Imaging and Radiation Sciences; Medical Radiation SciencesA σ1 receptor pharmacophore derived from a series of N-substituted 4-azahexacyclo[5.4.1.0(2,6).0(3,10).0(5,9).0(8,11)]dodecan-3-ols (AHDS), Bioorganic & Medicinal Chemistry Letters, vol.22, 19, 2012,pp 6053-6058