Browsing by Author Desai, Reena

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Issue DateTitleAuthor(s)Citation
2015Androgen actions via androgen receptor promote PTEN inactivation induced uterine cancerChoi, Jaesung Peter; Desai, Reena; Dong, Qihan; Handelsman, David; Simanainen, Ulla; Yao, Mu; Zheng, Yu; Watson, Geoffrey; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Medicine; Concord Clinical School: ANZAC Research InstituteAndrogen actions via androgen receptor promote PTEN inactivation induced uterine cancer, Endocrine-Related Cancer, vol.22, 5, 2015,pp 687-701
2014Androgen receptor inactivation resulted in acceleration in pubertal mammary gland growth, upregulation of ERα expression, and Wnt/β-catenin signaling in female miceDesai, Reena; Gao, Yan Ru (Ellen); Handelsman, David; Simanainen, Ulla; Walters, Kirsty; Zhou, Hong; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteAndrogen receptor inactivation resulted in acceleration in pubertal mammary gland growth, upregulation of ERα expression, and Wnt/β-catenin signaling in female mice, Endocrinology, vol.155, 12, 2014,pp 4951-4963
2012Androgen Resistance in Female Mice Increases Susceptibility to DMBA-Induced Mammary TumorsDesai, Reena; Gao, Yan; Handelsman, David; Jimenez, Mark; Simanainen, Ulla; Walters, Kirsty; Watson, Geoffrey W.; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteAndrogen Resistance in Female Mice Increases Susceptibility to DMBA-Induced Mammary Tumors, Hormones and Cancer, vol.3, 3, 2012,pp 113-124
2011Anterior prostate epithelial AR inactivation modifies estrogen receptor expression and increases estrogen sensitivityDesai, Reena; Gao, Yan; Handelsman, David; Jimenez, Mark; McNamara, Keely; Simanainen, Ulla; McPherson, Stephen; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteAnterior prostate epithelial AR inactivation modifies estrogen receptor expression and increases estrogen sensitivity, American Journal of Physiology: Endocrinology and Metabolism, vol.301, 4, 2011,pp E727-E735
2014Characterization of Reproductive, Metabolic, and Endocrine Features of Polycystic Ovary Syndrome in Female Hyperandrogenic Mouse ModelsAllan, Charles; Caldwell, A S L; Desai, Reena; Handelsman, David; Jimenez, Mark; McMahon, Aisling; Middleton, Linda; Walters, Kirsty; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteCharacterization of Reproductive, Metabolic, and Endocrine Features of Polycystic Ovary Syndrome in Female Hyperandrogenic Mouse Models, Endocrinology, vol.155, 8, 2014,pp 3146-3159
2013Characterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female miceAllan, Charles; Desai, Reena; Handelsman, David; Jimenez, Mark; Joseph, Shai; Middleton, Linda; Walters, Kirsty; Cheng, Xiaobing B.; Ning, Guang; Smith, J; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteCharacterizing the neuroendocrine and ovarian defects of androgen receptor-knockout female mice, American Journal of Physiology: Endocrinology and Metabolism (online), vol.305, 6, 2013,pp E717-E726
2016Elevated expression of the Sertoli cell androgen receptor disrupts male fertilityAllan, Charles; Desai, Reena; Handelsman, David; Hazra, Rasmani; Jimenez, Mark; Noori, O; Upton, Dannielle; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Medicine; Medical Imaging and Radiation SciencesElevated expression of the Sertoli cell androgen receptor disrupts male fertility, American Journal of Physiology: Endocrinology and Metabolism, vol.311, 2, 2016,pp e396-e404
2016Elevated expression of the Sertoli cell androgen receptor disrupts male fertilityAllan, Charles; Desai, Reena; Handelsman, David; Hazra, Rasmani; Jimenez, Mark; Noori, O; Upton, Dannielle; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Medicine; Medical Imaging and Radiation SciencesElevated expression of the Sertoli cell androgen receptor disrupts male fertility, American Journal of Physiology: Endocrinology and Metabolism, vol.311, 2, 2016,pp e396-e404
2012Endometrial and Endometriotic Concentrations of Estrone and Estradiol Are Determined by Local Metabolism Rather than Circulating LevelsDesai, Reena; Handelsman, David; Huhtinen, Kaisa; Perheentupa, Antti; Poutanen, M; Salmenin, Anu; Stahle, Mia; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteEndometrial and Endometriotic Concentrations of Estrone and Estradiol Are Determined by Local Metabolism Rather than Circulating Levels, Journal of Clinical Endocrinology and Metabolism, vol.97, 11, 2012,pp 4228-4235
2011Evaluation of androgenic activity of nutraceutical-derived steroids using mammalian and yeast in vitro androgen bioassaysAkram, Omar; Bursill, Christina; Handelsman, David; Heather, Alison; Desai, Reena; Kazlauskas, Rymantas; Lambert, Gilles; Central Clinical School: Heart Research Institute; Central Clinical School: Heart Research Institute; Concord Clinical School: ANZAC Research Institute; Central Clinical School: MedicineEvaluation of androgenic activity of nutraceutical-derived steroids using mammalian and yeast in vitro androgen bioassays, Analytical Chemistry, vol.83, 6, 2011,pp 2065-2074
2013Evidence for increased tissue androgen sensitivity in neurturin knockout miceDesai, Reena; Gao, Yan; Handelsman, David; Jimenez, Mark; Keast, Janet; Simanainen, Ulla; Spaliviero, Jennifer; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Northern Clinical School: Kolling Institute; Concord Clinical School: ANZAC Research Institute; Central Clinical School: MedicineEvidence for increased tissue androgen sensitivity in neurturin knockout mice, The Journal of Endocrinology, vol.218, 2, 2013,pp 151-163
2016Global or Granulosa Cell-Specific Pten Mutations in Combination with Elevated FSH Levels Fail to Cause Ovarian Tumours in MiceAllan, Charles; Desai, Reena; Handelsman, David; Jimenez, Mark; Upton, Dannielle; Walters, Kirsty; Allavena, Rachel; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Medical Imaging and Radiation Sciences; Concord Clinical School: ANZAC Research InstituteGlobal or Granulosa Cell-Specific Pten Mutations in Combination with Elevated FSH Levels Fail to Cause Ovarian Tumours in Mice, Hormones and Cancer, vol.7, N/A, 2016,pp 316-326
2014Glucocorticoid receptor in prostate epithelia is not required for corticosteroid-induced epithelial hyperproliferation in the mouse prostateChoi, Jaesung Peter; Desai, Reena; Gao, Yan Ru (Ellen); Handelsman, David; Jaehne, Maria; Simanainen, Ulla; Zhao, Bin; Zhou, Hong; Tuckermann, Jan; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteGlucocorticoid receptor in prostate epithelia is not required for corticosteroid-induced epithelial hyperproliferation in the mouse prostate, The Prostate, vol.74, 10, 2014,pp 1068-1078
2015Granulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors.Allan, Charles; Colvin, Emily; Desai, Reena; Fuller, Emily; Handelsman, David; Howell, Viive; Jimenez, Mark; Upton, Dannielle; Walters, Kirsty; Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling Institute; Concord Clinical School: ANZAC Research Institute; Western Clinical School: Medicine (Westmead); Concord Clinical School: ANZAC Research Institute; Northern Clinical School: Kolling Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteGranulosa Cell-Specific Brca1 Loss Alone or Combined with Trp53 Haploinsufficiency and Transgenic FSH Expression Fails to Induce Ovarian Tumors., Hormones and Cancer, vol.6, 4, 2015,pp 142-152
2015Haplosufficient genomic androgen receptor signaling is adequate to protect female mice from induction of polycystic ovary syndrome features by prenatal hyperandrogenization.Allan, Charles; Caldwell, A S L; Desai, Reena; Eid, S; Handelsman, David; Jimenez, Mark; McMahon, Aisling; Walters, Kirsty; Kay, C; Smith, Jeremy; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteHaplosufficient genomic androgen receptor signaling is adequate to protect female mice from induction of polycystic ovary syndrome features by prenatal hyperandrogenization., Endocrinology, vol.156, 4, 2015,pp 1441-1452
2014In Vivio Actions of the Sertoli Cell Glucocorticoid ReceptorAllan, Charles; Desai, Reena; Handelsman, David; Hazra, Rasmani; Jimenez, Mark; Upton, Dannielle; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research InstituteIn Vivio Actions of the Sertoli Cell Glucocorticoid Receptor, Endocrinology, vol.155, 3, 2014,pp 1120-1130
2014Intra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesionsDesai, Reena; Handelsman, David; Aittokallio, Tero; Awosanya, Michael; et al, Various; Häkkinen, Merja R; Huhtinen, Kaisa; Keski-Rahkonen, Pekka; Kujari, Harry; Laajala, Daniel; Saloniemi-Heinonen, Taija; Ståhle, Mia; Suvitie, Pia; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteIntra-tissue steroid profiling indicates differential progesterone and testosterone metabolism in the endometrium and endometriosis lesions, Journal of Clinical Endocrinology and Metabolism, vol.99, 11, 2014,pp E2188-E2197
2013LC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionizationDesai, Reena; Handelsman, David; Keski-Rahkonen, Pekka; Auriola, Seppo; Harwood, David; Huhtinen, Kaisa; Poutanen, M; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research InstituteLC-MS analysis of estradiol in human serum and endometrial tissue: Comparison of electrospray ionization, atmospheric pressure chemical ionization and atmospheric pressure photoionization, Journal of Mass Spectrometry, vol.48, 9, 2013,pp 1050-1058
2015Measurement of Estradiol in Human Serum by LC-MS/MS Using a Novel Estrogen-Specific Derivatization ReagentDesai, Reena; Handelsman, David; Harwood, D. Tim; Jimenez, Mark; Keski-Rahkonen, Pekka; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research InstituteMeasurement of Estradiol in Human Serum by LC-MS/MS Using a Novel Estrogen-Specific Derivatization Reagent, Analytical Chemistry, vol.87, 14, 2015,pp 7180-7186
2015Measurement of Testosterone by Immunoassays and Mass Spectrometry in Mouse Serum, Testicular, and Ovarian ExtractsDesai, Reena; Handelsman, David; Jimenez, Mark; Singh, Gurmeet; Spaliviero, Jennifer; Walters, Kirsty; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: Medicine; Concord Clinical School: ANZAC Research Institute; Central Clinical School: Medicine; Concord Clinical School: ANZAC Research InstituteMeasurement of Testosterone by Immunoassays and Mass Spectrometry in Mouse Serum, Testicular, and Ovarian Extracts, Endocrinology, vol.156, 1, 2015,pp 400-405