Browsing by Author Cowley, Mark

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Showing results 1 to 16 of 16
Issue DateTitleAuthor(s)Citation
2014c-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancerArmstrong, Nicola Joy; Naylor, Matthew; O'Toole, Sandra; Baker, Laura; Cowley, Mark; Herschkowitz, Jason I; Hui, Mun; Junankar, Simon; Kaplan, Warren; Lakhani, Sunil R.; McFarland, Andrea; Morey, Adrienne; Nair, Radhika; Nguyen, Akira; Nicolic, I; Ormandy, Christopher J.; Perou, Charles M; Pfefferle, Adam; Roden, Daniel; Selinger, Christina; Shah, Jaynish; Swarbrick, A.; Teo, W S; Usary, Jerry E; Yang, J; Ye, S; Mathematics & Statistics; School of Medical Sciences: Physiology; Central Clinical School: Pathologyc-Myc and Her2 cooperate to drive a stem-like phenotype with poor prognosis in breast cancer, Oncogene, vol.33, 30, 2014,pp 3992-4002
2013Clinical and molecular characterization of HER2 amplified-pancreatic cancerGill, Anthony; Toon, Christopher; Biankin, Andrew V.; Chang, David K.; Chantrill, Lorraine; Chin, Venessa; Chou, Angela; Cowley, Mark; Goldstein, David; Grimmond, Sean Michael; Humphris, Jeremy; Johns, Amber; Kassahn, Karin; Mead, Scott; Miller, David K; Morey, Adrienne; Musgrove, Elizabeth A.; Nagrial, Adnan; Nones, Katia; Pajic, Marina; Patch, Anne-Marie; Pearson, John V; Pinese, Mark; Rooman, Ilse; Samra, JS; Waddell, Nic; Wasan, Harpreet; Wu, Jianmin; Deans Unit: (CIPHER); Northern Clinical School: Kolling InstituteClinical and molecular characterization of HER2 amplified-pancreatic cancer, Genome Medicine, vol.5, 8, 2013,pp 1-11
2014Clinical and pathologic features of familial pancreatic cancerGill, Anthony; Kench, James; Samra, Jaswinder; Chang, David K.; Chantrill, Lorraine; Chin, Venessa; Cowley, Mark; et al, Various; Humphris, Jeremy; Johns, Amber L; Mead, Scott; Nagrial, Adnan; Pajic, Marina; Pinese, Mark; Simpson, Skye H; Northern Clinical School: Pathology; School of Medical Sciences: Pathology; Northern Clinical School: SurgeryClinical and pathologic features of familial pancreatic cancer, Cancer, vol.120, 23, 2014,pp 3669-3675
2016Defining the genetic basis of early onset hereditary spastic paraplegia using whole genome sequencingKumar, Kishore Raj; Roscioli, Tony; Sue, Carolyn; Wali, Gautam; Cowley, Mark; Dinger, Marcel; Gayevskiy, Velimir; Kamate, Mahesh; Minoche, Andre; Pinese, Mark; Puttick, Clare; Wali, G. M.; Northern Clinical School: Kolling Institute; Central Clinical School: Medicine; Northern Clinical School: Medicine; Northern Clinical School: Kolling InstituteDefining the genetic basis of early onset hereditary spastic paraplegia using whole genome sequencing, Neurogenetics, vol.17, 4, 2016,pp 265-270
2012ELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer.Naylor, Matthew; Allerdice, Stephanie; Caldon, C. E.; Cowley, Mark; et al, Various; Gallego-Ortega, David; Kalyuga, M; Launchbury, Rosalind; Lee, Heather; Roden, Daniel; Stone, Andrew; Valdes-Mora, Fatima; School of Medical Sciences: PhysiologyELF5 Suppresses Estrogen Sensitivity and Underpins the Acquisition of Antiestrogen Resistance in Luminal Breast Cancer., PLoS Biology, vol.10, 12, 2012,pp 1-17
2012Expression of pro- and anti-apoptotic molecules of the Bcl-2 family in human islets post-isolationHawthorne, Wayne; O'Connell, Philip; Ayala, Rochelle; Campbell, Peter; Chee, Jonathan; Cowley, Mark; Grey, Shane; Kay, Thomas W; Loudovaris, Thomas; Mariana, Lina; Thomas, Helen E; Weinberg, Anita; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteExpression of pro- and anti-apoptotic molecules of the Bcl-2 family in human islets post-isolation, Cell Transplantation, vol.21, 1, 2012,pp 49-60
2012Human islets express a marked proinflammatory molecular signature prior to transplantationAlexander, Stephen; Hawthorne, Wayne; O'Connell, Philip; Chapman, Jeremy R; Cowley, Mark; Grey, Shane; Gunton, Jenny; Kaplan, Warren; Kay, Thomas; Loudovaris, Thomas; Thomas, Helen; Walters, Stacey N; Weinberg, Anita; Zammit, Nathan W; Children's Hospital Westmead: Paediatrics & Child Health; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteHuman islets express a marked proinflammatory molecular signature prior to transplantation, Cell Transplantation, vol.21, 9, 2012,pp 2063-2078
2011Identification of Novel GH-Regulated Pathway of Lipid Metabolism in Adipose Tissue: A Gene Expression Study in Hypopituitary MenLee, Paul; Zhao, Jing; Birzniece, Vita; Cowley, Mark; Ho, Ken K Y; Kaplan, Warren; Concord Clinical School: Medicine; Biological SciencesIdentification of Novel GH-Regulated Pathway of Lipid Metabolism in Adipose Tissue: A Gene Expression Study in Hypopituitary Men, Journal of Clinical Endocrinology and Metabolism, vol.96, 7, 2011,pp E1188-E1196
2016JRK is a positive regulator of Beta-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancerParker, Benjamin Leo; Al-Sohaily, Sam; Benthani, F; Carey, Louise; Cowley, Mark; Currey, N; Giry-Laterriere, M; Kohonen-Corish, Maija R.J.; Morgan, A; Ng, I; Pangon, Laurent; Rooman, Ilse; Segelov, Eva; St Heaps, Luke; Tran, P; Wright, D C; Molecular BioscienceJRK is a positive regulator of Beta-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer, Oncogene, vol.35, 22, 2016,pp 2834-2841
2016JRK is a positive regulator of Beta-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancerParker, Benjamin Leo; Al-Sohaily, Sam; Benthani, F; Carey, Louise; Cowley, Mark; Currey, N; Giry-Laterriere, M; Kohonen-Corish, Maija R.J.; Morgan, A; Ng, I; Pangon, Laurent; Rooman, Ilse; Segelov, Eva; St Heaps, Luke; Tran, P; Wright, D C; Molecular BioscienceJRK is a positive regulator of Beta-catenin transcriptional activity commonly overexpressed in colon, breast and ovarian cancer, Oncogene, vol.35, 22, 2016,pp 2834-2841
2013Maternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic miceBuckland, Michael; Cooney, Gregory; Cowley, Mark; Cropley, Jennifer; Eaton, Sally; Febbraio, Mark; Henstridge, Darren; Li, Cheryl; Maloney, Christopher; Martin, David; Preiss, Thomas; Suter, Catherine; Young, Paul; School of Medical Sciences: Brain & Mind Research InstituteMaternal obesity and diabetes induces latent metabolic defects and widespread epigenetic changes in isogenic mice, Epigenetics, vol.8, 6, 2013,pp 602-611
2013A Preexistent Hypoxic Gene Signature Predicts Impaired Islet Graft Function and Glucose HomeostasisHawthorne, Wayne; O'Connell, Philip; Cantley, James; Cowley, Mark; Grey, Shane; Jung, Min-Ho; Kaplan, Warren; Walters, Stacey N; Weinberg, Anita; Weir, Gordon; Whitworth, P Tess; Western Clinical School: Westmead Millennium Institute; Western Clinical School: Westmead Millennium InstituteA Preexistent Hypoxic Gene Signature Predicts Impaired Islet Graft Function and Glucose Homeostasis, Cell Transplantation, vol.22, 11, 2013,pp 2147-2159
2012RON is not a prognostic marker for resectable pancreatic cancerGill, Anthony; Biankin, Andrew V.; Chang, David K.; Chou, Angela; Cowley, Mark; Daly, Roger; Grimmond, Sean; Humphrey, Emily; Nones, Katia; Sutherland, Robert L.; Tactacan, Carole; Wu, Jianmin; Northern Clinical School: PathologyRON is not a prognostic marker for resectable pancreatic cancer, BMC Cancer, vol.12, N/A, 2012,pp 1-9
2017A SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondrial disordersBalasubramaniam, Shanti; Christodoulou, John; Riley, Lisa; Sue, Carolyn; Bahlo, Melanie; Cowley, Mark; Gayevskiy, Velimir; Prelog, Kristina; Roscioli, T; Thorburn, David; Childrens Hospital Westmead: Medicine; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child Health; Northern Clinical School: MedicineA SLC39A8 variant causes manganese deficiency, and glycosylation and mitochondrial disorders, Journal of Inherited Metabolic Disease, vol.40, 2, 2017,pp 261-269
2013Somatic Point Mutation Calling in Low Cellularity TumorsGill, Anthony; Anderson, Matthew; Biankin, Andrew V.; Bruxner, Timothy; Chang, David K.; Christ, Angelika; Cowley, Mark; Fink, Lynn; Grimmond, Sean Michael; Harliwong, Ivon; Holmes, Oliver; Idrisoglu, Senel; Johns, Amber; Kassahn, Karin; Leonard, Conrad; Manning, Suzanne; Miller, David K; Newell, Felicity; Nones, Katia; Nourbakhsh, Eshan; Nourse, Craig; Pajic, Marina; Patch, Anne-Marie; Pearson, John V; Pinese, Mark; Song, Sarah; Steptoe, Anita; Taylor, Darrin; Waddell, Nicola; Wani, Shivangi; Wilson, Peter J; Wood, Scott; Wu, Jianmin; Xu, Qingying; Northern Clinical School: PathologySomatic Point Mutation Calling in Low Cellularity Tumors, PLoS One, vol.8, 11, 2013,pp 1-10
2017Unique presentation of cutis laxa with Leigh-like syndrome due to ECHS1 deficiencyBalasubramaniam, Shanti; Christodoulou, John; Riley, Lisa; Bratkovic, D; Cowley, Mark; Gardeitchik, T; Gayevskiy, Velimir; Ketteridge, D; Manton, N; Mohamed, M; Morava, E; Roscioli, Tony; Childrens Hospital Westmead: Medicine; Childrens Hospital Westmead: Paediatrics & Child Health; Childrens Hospital Westmead: Paediatrics & Child HealthUnique presentation of cutis laxa with Leigh-like syndrome due to ECHS1 deficiency, Journal of Inherited Metabolic Disease, vol.40, 5, 2017,pp 745-747