Browsing by Author Collins (Chebib), Mary

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Issue DateTitleAuthor(s)Citation
2012(1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine AddictionCollins (Chebib), Mary; Pera, Elena; Brauner-Osborne, Hans; Brodie, Jonathan; Craft, Cheryl; et al, various; Gerasimov, Madina; Kvist, Trine; Lee, Hyunbeom; Madsen, Karsten; Pan, Yue; Schousboe, Arne; Wellendorph, Petrine; Pharmacy; Pharmacy(1S, 3S)-3-Amino-4-difluoromethylenyl-1-cyclopentanoic Acid (CPP-115), a Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Cocaine Addiction, Journal of Medicinal Chemistry, vol.55, 1, 2012,pp 357-366
20122'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptorsCollins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Curmi, John; Tierney, Louise; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy2'-Methoxy-6-methylflavone: A novel anxiolytic and sedative with subtype selective activating and modulating actions at GABA(A) receptors, British Journal of Pharmacology, vol.165, 4, 2012,pp 880-896
20112-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-p1 ReceptorsAbdel-Halim, Heba; Collins (Chebib), Mary; Feng, Feng; Le Breton, Guy; Mir, Fozia; Pepperberg, David; Qian, Haohua; Standaert, Robert; Xie, An; Yan, Jun; Yue, Lan; Pharmacy; Pharmacy2-Aminoethyl Methylphosphonate, a Potent and Rapidly Acting Antagonist of GABAA-p1 Receptors, Molecular Pharmacology, vol.80, 6, 2011,pp 965-978
2007(3-Aminocyclopentyl)methylphosphinic acids: Novel GABA(C) receptor antagonistsCollins (Chebib), Mary; Hanrahan, Jane; Johnston, Graham; Kumar, Rohan; Mewett, Kenneth; Morriss, Gwendolyn; Wooller, Soraya; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy(3-Aminocyclopentyl)methylphosphinic acids: Novel GABA(C) receptor antagonists, Neuropharmacology (2005), vol.52,(3),2007,pp 779-787
20113-Hydroxy-2'-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABBA receptor subtypesCollins (Chebib), Mary; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Karim, Nasiara; Wellendorph, Petrine; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy3-Hydroxy-2'-methoxy-6-methylflavone: A potent anxiolytic with a unique selectivity profile at GABBA receptor subtypes, Biochemical Pharmacology, vol.82, 12, 2011,pp 1971-1983
20056-Methylflavanone, a more efficacious positive allosteric modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors expressed in Xenopus oocytes.Collins (Chebib), Mary; Hall, Belinda; Hanrahan, Jane; Johnston, Graham; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; School of Medical Sciences: Pharmacology6-Methylflavanone, a more efficacious positive allosteric modulator of gamma-aminobutyric acid (GABA) action at human recombinant alpha2beta2gamma2L than at alpha1beta2gamma2L and alpha1beta2 GABA(A) receptors expressed in Xenopus oocytes., European Journal of Pharmacology, vol.512,(2-3),2005,pp 97-104
2011Agonist responses of (R)- and (S)-3-fluoro-??-aminobutyric acids suggest an enantiomeric fold for GABA binding to GABA(C) receptorsCollins (Chebib), Mary; Gavande, Navnath; Johnston, Graham; Yamamoto, Izumi; Deniau, Gildas; O'Hagan, David; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyAgonist responses of (R)- and (S)-3-fluoro-??-aminobutyric acids suggest an enantiomeric fold for GABA binding to GABA(C) receptors, Chemical Communications, vol.47, 28, 2011,pp 7956-7958
2012(alpha)4(beta)(delta) GABAA receptors are high-affinity targets for gamma-hydroxybutyric acid (GHB)Absalom, Nathan; Collins (Chebib), Mary; Karim, Nasiara; Bay, Tina; Brauner-Osborne, Hans; Clausen, Rasmus; Eghorn, Laura; Frolund, Bente; Knudsen, Gitte; Olsen, Jesper; Villumsen, Inge; Wellendorph, Petrine; Pharmacy; Pharmacy; Pharmacy(alpha)4(beta)(delta) GABAA receptors are high-affinity targets for gamma-hydroxybutyric acid (GHB), Proceedings of the National Academy of Sciences (PNAS), vol.109, 33, 2012,pp 13404-13409
2003Aza-thip and related analogues of thip as GABAc antagonistsCollins (Chebib), Mary; Johnston, Graham; Ebert, Bjarke; Frølund, Bente; Krehan, Dorte; Krogsgaard-Larsen, Povl; Nielsen, Birgitte; Pharmacy; School of Medical Sciences: PharmacologyAza-thip and related analogues of thip as GABAc antagonists, Bioorganic & Medicinal Chemistry, vol.11,(23),2003,pp 4891-4896
2003Bilobalide, a sesquiterpene trilactone from ginkgo biloba, is an antagonist at recombinant a1b2y2l GABAA receptorsCollins (Chebib), Mary; Duke, Rujee; Huang, Shelley; Johnston, Graham; Sasaki, Keiko; Wada, Keiji; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyBilobalide, a sesquiterpene trilactone from ginkgo biloba, is an antagonist at recombinant a1b2y2l GABAA receptors, European Journal of Pharmacology, vol.464,(1),2003,pp 1-8
2004Charged Residues At The 2' Position Of Human GABAc ρ1 Receptors Invert Ion Selectivity And Influence Open State Probability.Carland, Jane; Collins (Chebib), Mary; Johnston, Graham; Moorhouse, Andrew; Barry, Peter H; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Medicine Faculty OfficeCharged Residues At The 2' Position Of Human GABAc ρ1 Receptors Invert Ion Selectivity And Influence Open State Probability., Journal of Biological Chemistry, vol.279,(52),2004,pp 54153-54160
2003Convulsant actions of CalycanthineCollins (Chebib), Mary; Connor, Mark; Duke, Colin; Duke, Rujee; Johnston, Graham; Mewett, Kenneth; Pharmacy; Northern Clinical School: Medicine; Pharmacy; School of Medical Sciences: Pharmacology; School of Medical Sciences: Pharmacology; School of Medical Sciences: PharmacologyConvulsant actions of Calycanthine, Toxicology and Applied Pharmacology, vol.190,(1),2003,pp 58-64
2012Covalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimidesAbsalom, Nathan; Collins (Chebib), Mary; Ambrus, Joseph; Balle, Thomas; Halliday, Jill; Harpsoe, Kasper; Kanizaj, Nicholas; McLeod, Malcolm; Pharmacy; PharmacyCovalent attachment of antagonists to the a7 nicotinic acetylcholine receptor: synthesis and reactivity of substituted maleimides, Chemical Communications, vol.48, 53, 2012,pp 6699-6701
2013Covalent trapping of methyllycaconitine at the alpha4-alpha4 interface of the apha4beta2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealedAbsalom, Nathan; Balle, Thomas; Collins (Chebib), Mary; Karim, Nasiara; Qudah, Taima; Quek, Gracia; von Arenstorff, Ida; Ambrus, Joseph; Harpsøe, Kasper; Lewis, Trevor M.; McLeod, Malcolm; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; Pharmacy; PharmacyCovalent trapping of methyllycaconitine at the alpha4-alpha4 interface of the apha4beta2 nicotinic acetylcholine receptor: antagonist binding site and mode of receptor inhibition revealed, The Journal of Biological Chemistry, vol.288, 37, 2013,pp 26521-26532
2011Dengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytesCollins (Chebib), Mary; Gowans, Eric J.; Haqshenas, Gholamreza; Loveland, Bruce; Wong, Sook-San; PharmacyDengue virus PrM/M proteins fail to show pH-dependent ion channel activity in Xenopus oocytes, Virology, vol.412, 1, 2011,pp 83-90
2013Design, synthesis, and pharmacological evaluation of fluorescent and biotinylated antagonists of P1 GABA(c) receptorsCollins (Chebib), Mary; Doddareddy, Munikumar; Gavande, Navnath; Hanrahan, Jane; Johnston, Graham; Kim, Hye-Lim; Pharmacy; School of Medical Sciences: Brain & Mind Research Institute; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; PharmacyDesign, synthesis, and pharmacological evaluation of fluorescent and biotinylated antagonists of P1 GABA(c) receptors, A C S Medicinal Chemistry Letters, vol.4, 4, 2013,pp 402-407
2006Diastereoselective synthesis of (+/-)-(3-aminocyclopentane)alkylphosphinic acids, conformationally restricted analogues of GABA.Burden, Peter; Collins (Chebib), Mary; Crean, Colm; Eliopoulos, Con; Hanrahan, Jane; Johnston, Graham; Kumar, Rohan; Matos, Susana; Mewett, Kenneth; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; Pharmacy; Pharmacy; School of Medical Sciences: Pharmacology; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyDiastereoselective synthesis of (+/-)-(3-aminocyclopentane)alkylphosphinic acids, conformationally restricted analogues of GABA., Organic & Biomolecular Chemistry, vol.4,(13),2006,pp 2642-2649
2004The Dietary Flavonoids Apigenin And (-)-Epigallocatechin Gallate Enhance The Positive Modulation By Diazepam Of The Activation By GABA Of Recombinant GABA(A) Receptors.Campbell, Erica; Collins (Chebib), Mary; Johnston, Graham; Pharmacy; Pharmacy; School of Medical Sciences: PharmacologyThe Dietary Flavonoids Apigenin And (-)-Epigallocatechin Gallate Enhance The Positive Modulation By Diazepam Of The Activation By GABA Of Recombinant GABA(A) Receptors., Biochemical Pharmacology, vol.68,(8),2004,pp 1631-1638
2006Double-Mannich annulation of cyclic ketones using N,N-bis(ethoxymethyl) alkylamine reagentsCollins (Chebib), Mary; Halliday, Jill; McLeod, Malcolm; Turner, Peter; Pharmacy; Chemistry; Chemistry; ChemistryDouble-Mannich annulation of cyclic ketones using N,N-bis(ethoxymethyl) alkylamine reagents, Organic Letters, vol.8,(15),2006,pp 3399-3401
2004Efficiency Considerations In The Construction Of Interpolated Potential Energy Surfaces For The Calculation Of Quantum Observables By Diffusion Monte CarloCollins (Chebib), Mary; Crittenden, Deborah; Jordan, Margaret; Thompson, Keiran; Pharmacy; Pharmacy; Pharmacy; ChemistryEfficiency Considerations In The Construction Of Interpolated Potential Energy Surfaces For The Calculation Of Quantum Observables By Diffusion Monte Carlo, The Journal of Physical Chemistry Part A: Molecules, Spectroscopy, Kinetics, Environment and General Theory, vol.121,(20),2004,pp 9844-9854