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Issue DateTitleAuthor(s)Citation
20151,8-Naphthalimide derivatives: new leads against dynamin I GTPase activityChau, Ngoc; Mariana, Anna; Robinson, Phillip; Abdel-Hamid, Mohammed; Macgregor, Kylie; McCluskey, Adam; Odell, Luke; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins1,8-Naphthalimide derivatives: new leads against dynamin I GTPase activity, Organic and Biomolecular Chemistry, vol.13, 29, 2015,pp 8016-8028
2014The ∼ 16 kDa C-terminal sequence of clathrin assembly protein AP180 is essential for efficient clathrin bindingChan, Ling-Shan; Graham, Mark; Moshkanbaryans, Lia; Xue, Jing; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsThe ∼ 16 kDa C-terminal sequence of clathrin assembly protein AP180 is essential for efficient clathrin binding, PloS One, vol.9, 10, 2014,pp 1-13
2013AAV-encoded OTC activity persisting to adulthood following delivery to newborn spfash mice is insufficient to prevent shRNA-induced hyperammonaemia.Alexander, Ian; Carpenter, Kevin; Cunningham, Sharon; Kok, Cindy; Spinoulas, Afroditi; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Medicine; Children's Hospital Westmead: Childrens Medical Research InsAAV-encoded OTC activity persisting to adulthood following delivery to newborn spfash mice is insufficient to prevent shRNA-induced hyperammonaemia., Gene Therapy, vol.20, 12, 2013,pp 1184-1187
2009Aberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning.Reddel, Roger; Clark, Susan; Hinshelwood, Rebecca A.; Huschtscha,, L; Melki, John; Paul, Cheryl; Song, Jenny Z.; Stirzaker, Clare; Children's Hospital Westmead: Childrens Medical Research InsAberrant de novo methylation of the p16INK4A CpG island is initiated post gene silencing in association with chromatin remodelling and mimics nucleosome positioning., Human Molecular Genetics, vol.18, 16,pp 3098-3109
2012Actin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletionRobinson, Phillip; Lavidis, N A; Maucort, Guillaume; McCluskey, Adam; Meunier, Frederic; Nguyen, Tam; Schenning, Mitja; Sullivan, Robert; Children's Hospital Westmead: Childrens Medical Research InsActin- and dynamin-dependent maturation of bulk endocytosis restores neurotransmission following synaptic depletion, PLoS One, vol.7, 5, 2012,pp 1-15
2009The actin-binding and bundling protein, EPLIN, is required for cytokinesisChircop, Megan; Graham, Mark; Ma, Maggie; Robinson, Phillip; Smith, Charlotte; Khanna, Kum Kum; Oakes, Vanessa; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsThe actin-binding and bundling protein, EPLIN, is required for cytokinesis, Cell Cycle, vol.8,(5),2009,pp 757-764
2013Activation of p53 following ionizing radiation, but not other stressors, is dependent on the proline-rich domain (PRD)Braithwaite, Antony; Campbell, Hamish; Mehta, Reena; Neumann, Axel; Rubio, Carina; Baird, Margaret; Slatter, T L; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsActivation of p53 following ionizing radiation, but not other stressors, is dependent on the proline-rich domain (PRD), Oncogene: including Oncogene Reviews, vol.32, 7, 2013,pp 827-836
2005Activation of the ALT pathway for telomere maintenance can affect other sequences in the human genome.Henson, J; Reddel, Roger R; Foxon, Jennifer L.; Jeffreys, Alec J.; Jeyapalan, Jennie N.; Pollock, Raphael E.; Royle, Nicola J.; Varley, Helen; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsActivation of the ALT pathway for telomere maintenance can affect other sequences in the human genome., Human Molecular Genetics, vol.14,(13),2005,pp 1785-1794
2011Adaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cellsSpeidel, Daniel; Barth, S; Breitling, R; Cinatl, J; Cinatl, Jr; Doerr, H W; Fehse, B; Löschmann, N; MacK, E; Michaelis, M; Rödel, F; Rothweiler, F; Stiewe, T; Van Rikxoort, M; Voges, Y; von Deimling, Andreas; Weber, Kristoffer; Children's Hospital Westmead: Childrens Medical Research InsAdaptation of cancer cells from different entities to the MDM2 inhibitor nutlin-3 results in the emergence of p53-mutated multi-drug-resistant cancer cells, Cell Death and Disease, vol.2, 12, 2011,pp e243 - 1-e243 - 8
2013Adeno-associated Virus-mediated Rescue of Neonatal Lethality in Argininosuccinate Synthetase-deficient MiceAlexander, Ian; Carpenter, Kevin; Cunningham, Sharon; Kuchel, Philip; Dane, Alison; Kok, Cindy; Logan, G; Siew, Susan; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Medicine; Children's Hospital Westmead: Childrens Medical Research Ins; Molecular BioscienceAdeno-associated Virus-mediated Rescue of Neonatal Lethality in Argininosuccinate Synthetase-deficient Mice, Molecular Therapy, vol.21, 10, 2013,pp 1823-1831
2010Alleviating Transcriptional Inhibition of the Norepinephrine Slc6a2 Transporter Gene in Depolarized NeuronsChristodoulou, John; Pelka, Gregory; Tam, Patrick; Bayles, Richard; Cappai, Roberto; Ciccotosto, Giuseppe D.; El-Osta, Assam; Harikrishnan, K. N.; Maxwell, Scott; Childrens Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Childrens Medical Research Institute (CMRI)Alleviating Transcriptional Inhibition of the Norepinephrine Slc6a2 Transporter Gene in Depolarized Neurons, The Journal of Neuroscience, vol.30, 4, 2010,pp 1494-1501
2009alpha-actinin-3 and performanceGarton, Fleur; North, Kathryn; Yang, Nan; Western Clinical School: Medicine (Westmead); Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Insalpha-actinin-3 and performance, Medicine and Sport Science, vol.54, N/A, 2009,pp 88-101
2010Alpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscleLek, Monkol; North, Kathryn; Quinlan, Kate; Seto, Jane; Yang, Nan; Cooney, Gregory; Floetenmeyer, Matthias; Macarthur, Daniel G; Parton, Robert G.; Raftery, Joanna M; Turner, Nigel; Vandebrouck, Aurelie; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research InsAlpha-actinin-3 deficiency results in reduced glycogen phosphorylase activity and altered calcium handling in skeletal muscle, Human Molecular Genetics, vol.19, 7,pp 1335-1346
2015Alpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a Δ133p53α mimicBraithwaite, Antony; Hood, Kylie; Hung, Noelyn; Royds, Janice; Sawhney, Sonal; Shaw, Alisha; Slatter, T L; Stubbs, Richard; Children's Hospital Westmead: Childrens Medical Research InsAlpha-enolase is upregulated on the cell surface and responds to plasminogen activation in mice expressing a Δ133p53α mimic, PloS One, vol.10, 2, 2015,pp 1-19
2005An alphaTropomyosin mutation alters dimer preference in nemaline myopathy.Cooper, Sandra; Corbett, Mark; Domazetovska, A; Gunning, Peter; Hardeman, Edna; North, Kathryn; Akkari, Anthony; Laing, Nigel G.; Western Clinical School: Medicine (Westmead); Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Paediatrics & Child HealthAn alphaTropomyosin mutation alters dimer preference in nemaline myopathy., Annals of Neurology, vol.57,(1),2005,pp 42-49
2004Alterations In The P16(Ink4A) And P53 Tumor Suppressor Genes Of Htert-Immortalized Human Fibroblasts.Clark, Susan; Melki, J; Reddel, Roger R; Zhong, Z; Neumann, Axel A; Noble, Jane R; Medicine; Central Clinical School: Medicine; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlterations In The P16(Ink4A) And P53 Tumor Suppressor Genes Of Htert-Immortalized Human Fibroblasts., Oncogene: including Oncogene Reviews, vol.23,(17),2004,pp 3116-3121
2003Alternative lengthening of telomeres and survival in patients with glioblastoma multiformeReddel, Roger R; Carroll, T.; Hakin-Smith, V.; Jellinek, D. A.; Levy, D.; McKay, Michael J.; Royds, Janice; Teo, M.; Timperley, W. R.; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres and survival in patients with glioblastoma multiforme, The Lancet, vol.361,(9360),2003,pp 836-838
2009Alternative lengthening of telomeres in human cellsPickett, Hilda; Reddel, Roger; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres in human cells in Telomeres and Telomerase in Cancer, Springer, 2009, pp. 127-148
2002Alternative lengthening of telomeres in mammalian cellsHenson, J; Neumann, Axel; Reddel, Roger; Yeager, Thomas R; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research InsAlternative lengthening of telomeres in mammalian cells, Oncogene: including Oncogene Reviews, vol.21, 4,pp 598-610
2008Alternative Lengthening of Telomeres in Mammalian CellsReddel, Roger; Cesare, Anthony J; Children's Hospital Westmead: Childrens Medical Research InsAlternative Lengthening of Telomeres in Mammalian Cells in Origin and Evolution of Telomeres, Landes Biosciences, 2008, pp. 45-57