Browsing by Author Becker, Thomas

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Issue DateTitleAuthor(s)Citation
2016The aPKC/Par3/Par6 polarity complex and membrane order are functionally inter-dependent in epithelia during vertebrate organogenesisBecker, Thomas; Rinkwitz, Silke; Abu-Siniyeh, Ahmad; Benzing, Carola; Gaus, Katharina; Majumdar, Arindam; Owen, Dylan M.; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentreThe aPKC/Par3/Par6 polarity complex and membrane order are functionally inter-dependent in epithelia during vertebrate organogenesis, Traffic (Malden), vol.17, 1, 2016,pp 66-79
2014ARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctionsBecker, Thomas; Chang, Garry Hoi-Kai; Coleman, Paul; Formaz-Preston, Ann; Gamble, Jennifer; Jolly, Christopher; Lay, Angelina; Powter, Elizabeth; Rinkwitz, Silke; Ting, Ka Ka; Vadas, Mathew; Zhao, Yang; Bower, Neil; Hogan, Benjamin; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; School of Medical Sciences: Brain & Mind Research Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteARHGAP18: an endogenous inhibitor of angiogenesis, limiting tip formation and stabilizing junctions, Small GTPases, vol.5, 3, 2014,pp 1-15
2015BAC Transgenic Zebrafish Reveal Hypothalamic Enhancer Activity Around Obesity Associated SNP rs9939609 Within the Human FTO GeneBecker, Thomas; Geng, Fansuo; Manning, Elizabeth; Rinkwitz, Silke; Kawakami, Koichi; Suster, Maximiliano; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Medicine; School of Medical Sciences: Brain and Mind CentreBAC Transgenic Zebrafish Reveal Hypothalamic Enhancer Activity Around Obesity Associated SNP rs9939609 Within the Human FTO Gene, Genesis, vol.53, 10, 2015,pp 640-651
2017Calpain inhibition is protective in machado`joseph disease zebrafish due to induction of autophagyBecker, Thomas; Goldsbury, Claire; Mackovski, Nikolce; Nicholson, Garth; Rinkwitz, Silke; Watchon, Maxinne; Cole, Nicholas; Laird, Angela; Svahn, Adam; Yuan, Kristy; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; Concord Clinical School: ANZAC Research Institute; Concord Clinical School: ANZAC Research Institute; School of Medical Sciences: Brain and Mind Centre; Concord Clinical School: ANZAC Research InstituteCalpain inhibition is protective in machado`joseph disease zebrafish due to induction of autophagy, Journal of Neuroscience, vol.37, 32, 2017,pp 7782-7794
2013Chemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophyBecker, Thomas; Giacomotto, Jean; Berger, Joachim; Brouilly, Nicolas; Currie, Peter; Gieseler, Kathrin; Mariol, Marie-Christine; Segalat, Laurent; Walter, Ludivine; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteChemical genetics unveils a key role of mitochondrial dynamics, cytochrome c release and IP3R activity in muscular dystrophy, Human Molecular Genetics, vol.22, 22, 2013,pp 4562-4578
2009Cis-regulation and chromosomal rearrangement of the fgf8 locus after the teleost/tetrapod split.Becker, Thomas; Komisarczuk, Anna; Kawakami, Koichi; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteCis-regulation and chromosomal rearrangement of the fgf8 locus after the teleost/tetrapod split., Developmental Biology, vol.336, 2,pp 301-312
2010Cis-regulatory characterization of sequence conservation surrounding the Hox4 genesBecker, Thomas; Punnamoottil, Beena; Rinkwitz, Silke; Akalin, Altuna; D'Aniello, Salvatore; Garcia-Fernandez, Jordi; Herrmann, Carl; Pascual-Anaya, Juan; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteCis-regulatory characterization of sequence conservation surrounding the Hox4 genes, Developmental Biology, vol.340, 2,pp 269-282
2015Copy number variants in patients with intellectual disability affect the regulation of ARX transcription factor geneBecker, Thomas; Giacomotto, Jean Georges Marie; Ishibashi, Minaka; Manning, Elizabeth; Mechaly Garcia, Alejandro Sebastian; Rinkwitz, Silke; Zhao, Ting; Bader, Patricia I; Bain, Nicole L; Cheung, Sau W; et al, Various; Hackett, Anna; Hawkins, Thomas; Krecsmarik, Monika; Mueller, Thomas; Reddy, Chilamakuri C S; Shoubridge, C; Stankiewicz, Pawel; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Medicine; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentreCopy number variants in patients with intellectual disability affect the regulation of ARX transcription factor gene, Human Genetics, vol.134, 11, 2015,pp 1163-1182
2013Development of Ramified Microglia from Early Macrophages in the Zebrafish Optic TectumBecker, Thomas; Bennett, Maxwell; Graeber, Manuel; Rinkwitz, Silke; Svahn, Adam; Ellett, Felix; Lieschke, Graham; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Physiology; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteDevelopment of Ramified Microglia from Early Macrophages in the Zebrafish Optic Tectum, Developmental Neurobiology, vol.73, 1, 2013,pp 60-71
2016Diversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organsBecker, Thomas; Komisarczuk, Anna; Abe, Keiko; Jouary, Adrien; Kapsimali, Marika; Kaushik, Anna-Lila; Lardennois, Alicia; Lourenco, Raquel; Mathieu, Benjamin; Okada, Shinji; Romano, Sebastian; Soulika, Marina; Tissot, Nicolas; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentreDiversity in cell motility reveals the dynamic nature of the formation of zebrafish taste sensory organs, Development, vol.143, 11, 2016,pp 2012-2024
2015Effective heritable gene knockdown in zebrafish using synthetic microRNAsBecker, Thomas; Giacomotto, Jean Georges Marie; Rinkwitz, Silke; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentreEffective heritable gene knockdown in zebrafish using synthetic microRNAs, Nature Communications, vol.6, N/A, 2015,pp 1-11
2014Emergent properties of microgliaBecker, Thomas; Graeber, Manuel; Svahn, Adam; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteEmergent properties of microglia, Brain Pathology, vol.24, 6, 2014,pp 665-670
2011Hindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4Becker, Thomas; Bouchoucha, Yassune Xavier; Charnay, Patrick; Gilardi-Hebenstreit, Pascale; Gongal, Patricia Anne; Labalette, Charlotte; Le Men, Johan; Wassef, Michel Adam; School of Medical Sciences: Brain & Mind Research InstituteHindbrain patterning requires fine-tuning of early krox20 transcription by Sprouty 4, Development (Cambridge), vol.138, 2, 2011,pp 317-326
2012Identification of a melanocyte-specific, microphthalmia-associated transcription factor-dependent regulatory element in the intronic duplication causing hair greying and melanoma in horsesBecker, Thomas; Komisarczuk, Anna; Rinkwitz, Silke; Andersson, Leif; Golovko, Anna; Jiang, Lin; Navratilova, Pavla; Sundstrom, Elisabeth; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteIdentification of a melanocyte-specific, microphthalmia-associated transcription factor-dependent regulatory element in the intronic duplication causing hair greying and melanoma in horses, Pigment Cell and Melanoma Research, vol.25, 1, 2012,pp 28-36
2015Long-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosomeBecker, Thomas; Ishibashi, Minaka; Manning, Elizabeth; Rinkwitz, Silke; Bally-Cuif, Laure; Bengani, Hemant; Chilamakuri, Chandra Sekhar Reddy; Crollius, Hugues; Ferg, Marco; Fitzpatrick, David; Hawkins, Thomas; Krecsmarik, Monika; Lenhard, Boris; Louis, Alexandra; Naville, Magali; Rastegar, Sepand; Raymond, F. Lucy; Strahle, Uwe; Van Heyningen, Veronica; Wilson, David I.; Wilson, Stephen; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Medicine; School of Medical Sciences: Brain and Mind CentreLong-range evolutionary constraints reveal cis-regulatory interactions on the human X chromosome, Nature Communications, vol.6, N/A, 2015,pp 1-9
2010Long-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3.Becker, Thomas; Alonso, M. Eva; de la Calle Mustienes, Elisa; Drivenes, Oyvind; Engstrom, Paer G.; et al, various; Fredman, David; Gomez Skarmeta, Jose Luis; Moro, Enrico; Navratilova, Pavla; Ragvin, Anja; School of Medical Sciences: Brain & Mind Research InstituteLong-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3., Proceedings of the National Academy of Sciences, vol.107, 2,pp 775-780
2016miR-124 contributes to the functional maturity of microgliaBecker, Thomas; Giacomotto, Jean Georges Marie; Graeber, Manuel; Rinkwitz, Silke; Svahn, Adam; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentremiR-124 contributes to the functional maturity of microglia, Developmental Neurobiology, vol.76, 5, 2016,pp 507-518
2012Morphogenesis underlying the development of the everted teleost telencephalonBecker, Thomas; Navratilova, Pavla; Bayley, Philippa; Clarke, Jonathan; Folgueira, Monica; Wilson, Stephen; School of Medical Sciences: Brain & Mind Research Institute; School of Medical Sciences: Brain & Mind Research InstituteMorphogenesis underlying the development of the everted teleost telencephalon, Neural Development, vol.7, 1, 2012,pp 1-13
2015Motor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes.Becker, Thomas; Giacomotto, Jean Georges Marie; Punnamoottil, Beena; Rinkwitz, Silke; Svahn, Adam; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind Centre; School of Medical Sciences: Brain and Mind CentreMotor neuron-expressed microRNAs 218 and their enhancers are nested within introns of Slit2/3 genes., Genesis, vol.53, 5, 2015,pp 321-328
2015Mutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organizationBecker, Thomas; Cheng, Anson; Greenlees, Rebecca; Grigg, John; Jamieson, Robyn; Loebel, David; Ma, Alan; Mihelec, Marija; Nash, Benjamin; Prokudin, Ivan; Rinkwitz, Silke; Speidel, Daniel; Tam, Patrick; Yousoof, Saira Bahnu Mohamed; Black, Graeme C M; Clayton-Smith, Jill; Gillespie, Rachel; Lloyd, I. Christopher; Perveen, Rahat; Semina, Elena; Wu, Selwin K; Yap, Alpha; School of Medical Sciences: Brain and Mind Centre; Central Clinical School: Save Sight & Eye Health Inst.; Biological Sciences; Central Clinical School: Clinical Ophthal & Eye Health; Childrens Hospital Westmead: Paediatrics & Child Health; Children's Hospital Westmead: Childrens Medical Research Ins; School of Medical Sciences: Pathology; Central Clinical School: Save Sight & Eye Health Inst.; Children's Hospital Westmead: Childrens Medical Research Ins; Central Clinical School: Ophthalmology & Eye Health; School of Medical Sciences: Brain and Mind Centre; Children's Hospital Westmead: Childrens Medical Research Ins; Children's Hospital Westmead: Childrens Medical Research Ins; SAHCS: Clinical Ophthalmology and Eye HealthMutations in SIPA1L3 cause eye defects through disruption of cell polarity and cytoskeleton organization, Human Molecular Genetics, vol.24, 20, 2015,pp 5789-5804