Browsing by Author Austin, Christopher

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Issue DateTitleAuthor(s)Citation
20101-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophanAustin, Christopher; Ball, Helen; Hunt, Nicholas; Yuasa, Hajime J.; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology1-L-methyltryptophan is a more effective inhibitor of vertebrate IDO2 enzymes than 1-D-methyltryptophan, Comparative Biochemistry and Physiology. Part B: Biochemistry and Molecular Biology, vol.157, 1, 2010,pp 10-15
2010Biochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2Arthur, Jonathan; Austin, Christopher; Ball, Helen; Hunt, Nicholas; Maghzal, Ghassan; Sanchez-Perez, Angeles; Stocker, Roland; Becker, K; Mailu, B.M.; Rahlfs, S; Yuasa, Hajime J.; Zocher, K; Children's Hospital Westmead: Childrens Medical Research Ins; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyBiochemical characteristics and inhibitor selectivity of mouse indoleamine 2,3-dioxygenase-2, Amino Acids, vol.39, 2,pp 565-578
2015Carborane-containing hydroxyamidine scaffolds as novel inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1)Austin, Christopher; Kahlert, Jan; Kassiou, Michael; Moir, Michael; Rendina, Louis; Jamie, Joanne; Smith, Jason R.; Chemistry; Chemistry; Medical Imaging and Radiation Sciences; Chemistry; ChemistryCarborane-containing hydroxyamidine scaffolds as novel inhibitors of indoleamine 2,3-dioxygenase 1 (IDO1), Australian Journal of Chemistry: an international journal for chemical science, vol.68, 12, 2015,pp 1866-1870
2009Characterization and evolution of vertebrate indoleamine 2, 3-dioxygenases. IDOs from monotremes and marsupialsAustin, Christopher; Ball, Helen; Belov, Katherine; Ho, Yuen; Hunt, Nicholas; Jermiin, Lars; Maghzal, Ghassan; Whittington, Camilla; Yuasa, Hajime; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Vet Science Faculty; Central Clinical School: Pathology; School of Medical Sciences: Pathology; Biological Sciences; School of Medical Sciences: Pathology; REPROGEN; School of Medical Sciences: PathologyCharacterization and evolution of vertebrate indoleamine 2, 3-dioxygenases. IDOs from monotremes and marsupials, Comparative Biochemistry and Physiology. Part B: Biochemistry & Molecular Biology, vol.153,(2),2009,pp 137-144
2007Characterization of an indoleamine 2,3-dioxygenase-like protein found in humans and miceAstelbauer, Florian; Austin, Christopher; Ball, Helen; Hunt, Nicholas; Jermiin, Lars; McQuillan, James; Miu, Jenny; Sanchez-Perez, Angeles; Stocker, Roland; Weiser, Silvia; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Biological Sciences; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyCharacterization of an indoleamine 2,3-dioxygenase-like protein found in humans and mice, Gene, vol.396,(1),2007,pp 203-213
2014The Fe-heme structure of met-indoleamine 2,3-dioxygenase-2 determined by X-ray absorption fine structureAitken, Jade; Austin, Christopher; Ball, Helen; Hunt, Nicholas; Lay, Peter; Chemistry; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; ChemistryThe Fe-heme structure of met-indoleamine 2,3-dioxygenase-2 determined by X-ray absorption fine structure, Biochemical and Biophysical Research Communications, vol.450, 1, 2014,pp 25-29
2013The fifth element in drug design: Boron in medicinal chemistryAustin, Christopher; Kahlert, Jan; Kassiou, Michael; Rendina, Louis; Chemistry; Chemistry; Medical Imaging and Radiation Sciences; ChemistryThe fifth element in drug design: Boron in medicinal chemistry, Australian Journal of Chemistry: an international journal for chemical science, vol.66, 10, 2013,pp 1118-1123
2014The first indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors containing carboraneAustin, Christopher; Hibbs, David; Ioppolo, Joseph; Issa, Fatiah; Kahlert, Jan; Ong, Jennifer; Reed, John Henry; Rendina, Louis; Jamie, Joanne; Smith, Jason R.; Chemistry; Pharmacy; Chemistry; Chemistry; Chemistry; Pharmacy; Chemistry; ChemistryThe first indoleamine-2,3-dioxygenase-1 (IDO1) inhibitors containing carborane, Dalton Transactions, vol.43, 28, 2014,pp 10719-10724
2008Indoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathwayAustin, Christopher; Ball, Helen; Hunt, Nicholas; Weiser, Silvia; Yuasa, Hajime; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyIndoleamine 2,3-dioxygenase-2; a new enzyme in the kynurenine pathway, The International Journal of Biochemistry & Cell Biology, vol.41,(3),2008,pp 467-471
2013Molecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia: Activation of the Integrated Stress Response, eIF2a Phosphorylation, and the Induction of Downstream TargetsAustin, Christopher; Huang, Michael; Jansson, Jan (Patric); Kelly, Matthew; Richardson, Desi (Des); Semsarian, Chris; Sivagurunathan, Sutharshani; Ting, Samantha; Zhang, Daohai; Chemistry; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; Anaesthesia; School of Medical Sciences: Pathology; Central Clinical School: Centenary Institute; School of Medical Sciences: Physiology; Central Clinical School: Pathology; School of Medical Sciences: PathologyMolecular and Functional Alterations in a Mouse Cardiac Model of Friedreich Ataxia: Activation of the Integrated Stress Response, eIF2a Phosphorylation, and the Induction of Downstream Targets, The American Journal of Pathology: cellular and molecular biology of disease, vol.183, 3, 2013,pp 745-757
2008Mouse and human indoleamine 2,3-dioxygenase display some distinct biochemical and structural propertiesAstelbauer, Florian; Austin, Christopher; Ball, Helen; Hunt, Nicholas; Jamie, Joanne F.; Kosim-Satyaputra, Priambudi; Willows, Robert D.; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: Pathology; School of Medical Sciences: PathologyMouse and human indoleamine 2,3-dioxygenase display some distinct biochemical and structural properties, Amino Acids, vol.36,(1),2008,pp 99-106
2013Mutation of cysteine residues alters the heme-binding pocket of indoleamine 2,3-dioxygenase-1Austin, Christopher; Jamie, Joanne F.; Kosim-Satyaputra, Priambudi; Smith, Jason R.; Willows, Robert D.; ChemistryMutation of cysteine residues alters the heme-binding pocket of indoleamine 2,3-dioxygenase-1, Biochemical and Biophysical Research Communications, vol.436, 4, 2013,pp 595-600
2016Site-specific synthesis of a hybrid boron-graphene saltAustin, Christopher; Choucair, Mohammad; Hall, Andrew; Kahlert, Jan; Rendina, Louis; Hook, James M; Rawal, Aditya; Chemistry; Chemistry; Chemistry; Chemistry; ChemistrySite-specific synthesis of a hybrid boron-graphene salt, Chemical Communications, vol.52, 6, 2016,pp 1290-1292
2013Synchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cellsAitken, Jade; Austin, Christopher; Jolliffe, Katrina; Rendina, Louis; Ziolkowski (Sheridan), Erin; Harris, Hugh H; Vogt, Stefan; Chemistry; Chemistry; Chemistry; Chemistry; ChemistrySynchrotron X-ray fluorescence studies of a bromine-labelled cyclic RGD peptide interacting with individual tumor cells, Journal of Synchrotron Radiation, vol.20, 2, 2013,pp 226-233
2015Targeting key dioxygenases in tryptophan-kynurenine metabolism for immunomodulation and cancer chemotherapyAustin, Christopher; Rendina, Louis; Chemistry; ChemistryTargeting key dioxygenases in tryptophan-kynurenine metabolism for immunomodulation and cancer chemotherapy, Drug Discovery Today, vol.20, 5, 2015,pp 609-617
2013The translocator protein (TSPO): A novel target for cancer chemotherapyAustin, Christopher; Kahlert, Jan; Kassiou, Michael; Rendina, Louis; Chemistry; Chemistry; Medical Imaging and Radiation Sciences; ChemistryThe translocator protein (TSPO): A novel target for cancer chemotherapy, The International Journal of Biochemistry and Cell Biology, vol.45, 7, 2013,pp 1212-1216