Browsing by Author Shackel, Nicholas

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Issue DateTitleAuthor(s)Citation
2009Early High Peak Hepatitis C Viral Load Levels Independently Predict Hepatitis C–Related Liver Failure Post–Liver TransplantationJamias, Jade; Koorey, David; McCaughan, Geoffrey William; Prakoso, Emilia; Rahman, Wassim; Shackel, Nicholas; Strasser, Simone; Crawford, Michael; Gallagher, James; Verran, Deborah J.; Other or Unknown; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: MedicineEarly High Peak Hepatitis C Viral Load Levels Independently Predict Hepatitis C–Related Liver Failure Post–Liver Transplantation, Liver Transplantation, vol.15, 7, 2009,pp 709-718
2016Extracellular vesicles: A new frontier in biomarker discovery for non-alcoholic fatty liver diseaseBan, Linda; McLennan, Susan; Shackel, Nicholas; Central Clinical School: Medicine; Central Clinical School: MedicineExtracellular vesicles: A new frontier in biomarker discovery for non-alcoholic fatty liver disease, International Journal of Molecular Sciences, vol.17, 3, 2016,pp 1-14
2002Gene array analysis and the liverGorrell, Mark; McCaughan, Geoffrey; Shackel, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteGene array analysis and the liver, Hepatology, vol.36,(6),2002,pp 1313-1325
2012Grade of Deceased Donor Liver Macrovesicular Steatosis Impacts Graft and Recipient Outcomes More than Donor Risk IndexKench, James; McCaughan, Geoffrey; Pleass, Henry; Shackel, Nicholas; Strasser, Simone; Crawford, Michael; Dilworth, Pamela; Graaf, Esther; Joseph, David; Verran, Deborah J.; School of Medical Sciences: Pathology; Central Clinical School: Centenary Institute; Western Clinical School: Surgery; Central Clinical School: Centenary Institute; Central Clinical School: MedicineGrade of Deceased Donor Liver Macrovesicular Steatosis Impacts Graft and Recipient Outcomes More than Donor Risk Index, Journal of Gastroenterology and Hepatology, vol.27, 3, 2012,pp 540-546
2017HBV DNA integration: Molecular mechanisms and clinical implicationsBudzinska, Magdalena A; Shackel, Nicholas; Tu, T; Urban, S; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteHBV DNA integration: Molecular mechanisms and clinical implications, Viruses, vol.9, 4, 2017,pp 1-18
2015Hepatic Artery Stenosis After Liver Transplantation: Is Endovascular Treatment Always Necessary?McCaughan, Geoffrey William; Pulitano, Carlo; Shackel, Nicholas; Crawford, Michael; Joseph, David; Sandroussi, Charbel; Strasser, Simone; Verran, Deborah J.; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary InstituteHepatic Artery Stenosis After Liver Transplantation: Is Endovascular Treatment Always Necessary?, Liver Transplantation, vol.21, 2, 2015,pp 162-168
2006The hepatic transcriptome in human liver disease.Gorrell, Mark; Haber, Paul; McCaughan, Geoffrey; Seth, Devanshi; Shackel, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Addiction Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe hepatic transcriptome in human liver disease., Comparative Hepatology, vol.5,(N/A),2006,pp 6-6
2008Hepatocellular carcinoma development requires hepatic stem cells with altered transforming growth factor and interleukin-6 signaling.McCaughan, Geoffrey; Shackel, Nicholas; Warner, Fiona; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteHepatocellular carcinoma development requires hepatic stem cells with altered transforming growth factor and interleukin-6 signaling., Hepatology, vol.47,(6),2008,pp 2134-2136
2014Hepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver FibrogenesisCalabro, Sarah; D'Avigdor, William; Lee, Maggie; Maczurek, Annette; McCaughan, Geoffrey William; McLennan, Susan; Morgan, Alison; Mridha, Auvro; Shackel, Nicholas; Tu, Thomas; Warner, Fiona; Wen, Victoria; Yee, Christine; Locarnini, S; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; School of Medical Sciences: Pathology; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Vet Science Faculty; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteHepatocyte Produced Matrix Metalloproteinases Are Regulated by CD147 in Liver Fibrogenesis, PloS One, vol.9, 7, 2014,pp e90571-N/A
2015Hepatocytes in liver injury: victim, bystander, or accomplice in progressive fibrosis?Budzinska, Magdalena A; Calabro, Sarah; Lee, Aimei; Maczurek, Annette; McLennan, Susan; Shackel, Nicholas; Tu, Thomas; Warner, Fiona; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteHepatocytes in liver injury: victim, bystander, or accomplice in progressive fibrosis?, Journal of Gastroenterology and Hepatology, vol.30, 12, 2015,pp 1696-1704
2007Identification of Resident Hepatic Stem Cell PopulationsShackel, Nicholas; Warner, Fiona; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteIdentification of Resident Hepatic Stem Cell Populations, Hepatology, vol.46,(N/A),2007,pp 2042-2044
2018Immune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical ManagementChua, Elizabeth; Lowe, Patricia; McGill, Neil; McNeil, Catriona; Shackel, Nicholas; Sweeting, Arianne Natasha; Cheng, R; Lim, Jennifer; Lomax, Anna J.; Central Clinical School: Medicine; Anaesthesia; Central Clinical School: Medicine; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Boden InstituteImmune Toxicity with Checkpoint Inhibition for Metastatic Melanoma: Case Series and Clinical Management, Journal of Skin Cancer, vol.2018, N/A, 2018,pp 9602540-N/A
2002Insights into the pathobiology of hepatitis C virus-associated cirrhosisGorrell, Mark; McCaughan, Geoffrey; Shackel, Nicholas; Abbott, Catherine A.; McGuinness, Peter H.; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteInsights into the pathobiology of hepatitis C virus-associated cirrhosis, American Journal of Pathology, vol.160,(2),2002,pp 641-654
2014The intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injuryMcCaughan, Geoffrey William; Shackel, Nicholas; Ajami, Katerina; Calabro, Sarah; Dwyer, Benjamin; Grzelak, Candice; Martelotto, Luciano G.; Patkunanathan, Bramilla; Sigglekow, Nicholas; Tirnitz-Parker, Janina; Warner, Fiona; Watkins, D. Neil; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteThe intrahepatic signalling niche of hedgehog is defined by primary cilia positive cells during chronic liver injury, Journal of Hepatology, vol.60, 1, 2014,pp 143-151
2015Ipilimumab-induced toxicities and the gastroenterologistKench, James; McNeil, Catriona; Shackel, Nicholas; Bye, William; Cheng, Robert; Cooper, Adam; Watson, Geoffrey; School of Medical Sciences: Pathology; Western Clinical School: Medicine (Westmead); Central Clinical School: Centenary InstituteIpilimumab-induced toxicities and the gastroenterologist, Journal of Gastroenterology and Hepatology, vol.30, 4, 2015,pp 657-666
2016Longitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphomtery in comparison to serum markersPatel, Keyur; Shackel, Nicholas; Gardner, Stephen; Goodman, Zachary D; Matta, Bassem N; McHutchison, John; Sheridan, M J; Tillmann, H; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteLongitudinal assessment of hepatitis C fibrosis progression by collagen and smooth muscle actin morphomtery in comparison to serum markers, Alimentary Pharmacology and Therapeutics, vol.43, 3, 2016,pp 356-363
2015Lower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity.Brooks, Belinda; Gorrell, Mark; Keane, Fiona; McCaughan, Geoffrey William; McLennan, Susan; Prakoso, Emilia; Shackel, Nicholas; Twigg, Stephen; Veillard, Anne-Sophie; Vieira de Ribeiro, Ana; Williams, Kathryn; Bachovchin, William; Bu, Yagmin; Cavanagh, E; Raleigh, J; Zekry, Amany; Clinical Nursing; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; NH&MRC Clinical Trials Centre; Central Clinical School: Centenary Institute; Central Clinical School: MedicineLower serum fibroblast activation protein shows promise in the exclusion of clinically significant liver fibrosis due to non-alcoholic fatty liver disease in diabetes and obesity., Diabetes Research and Clinical Practice, vol.108, 3, 2015,pp 466-472
2010Minimal but significant improvement in survival for non-hepatitis C-related adult liver transplant patients beyond the one-year posttransplant markDilworth, Pamela; McCaughan, Geoffrey; Shackel, Nicholas; Strasser, Simone; Tang, Patrick; Central Clinical School: Medicine; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Medicine; Central Clinical School: MedicineMinimal but significant improvement in survival for non-hepatitis C-related adult liver transplant patients beyond the one-year posttransplant mark, Liver Transplantation, vol.16, 2,pp 130-137
2015miR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancerBowen, David; Gamble, Jennifer; Shackel, Nicholas; Vadas, Mathew; Bertolino, Patrick; Brockhausen, Jennifer; d'Avigdor, William M; Grzelak, Candice; McCaughan, Geoffrey W.; Pok, Sharon; Tay, Szun Szun; Teoh, Narci C; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstitutemiR-181a mediates TGF-β-induced hepatocyte EMT and is dysregulated in cirrhosis and hepatocellular cancer, Liver International, vol.35, 1, 2015,pp 240-253
2009Molecular and cellular aspects of hepatitis C virus reinfection after liver transplantation: how the early phase impacts on outcomesBertolino, Patrick; Bowen, David; McCaughan, Geoffrey; Shackel, Nicholas; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary Institute; Central Clinical School: Centenary InstituteMolecular and cellular aspects of hepatitis C virus reinfection after liver transplantation: how the early phase impacts on outcomes, Transplantation, vol.87, 8,pp 1105-1111